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Biomedical subjects

L A Sidrys

Publications and source records attributed to L A Sidrys.

9 recordsLinked to original sources

Epithelial downgrowth after penetrating keratoplasty.

Epithelial downgrowth after penetrating keratoplasty in very uncommon. This paper describes a case in which epithelium invaded the anterior chamber through a fistula in the suture scar from a cataract operation 15 years previously. The epithelium completely circled the endothelial margin of the corneal graft but did not advance into the centre of the graft. Traumatized corneal endothelial cells lose their property of contact inhibition, which permits epithelial growth, whereas normal endothelium is able to resist epithelial downgrowth.

Aged↗

Separation of the iris pigment epithelium.

Surgical repair of traumatic corneal and scleral lacerations with uveal prolapse postoperatively disclosed a separation of the pigment epithelium. Posterior synechiae and a dense occlusion of the pupil tightly bound the papillary margin to the lens capsule. Traumatic, surgical, and mydriatic agents tore the anterior pigment epithelium layer loose from the adherent pupillary margin and induced a complete separation of the iris along the original lumen of the embryonic cup, between the two epithelial layers. Once the consolidated fibrin cleared, the posterior pigment layer retraccted from the visual axis but did not reattach to the iris.

Adult↗

Congenital bilateral horizontal gaze palsy in a brother and sister.

A man of 21 years and his sister aged 20 years had congenital bilateral horizontal gaze palsy. Convergence was normal but the vestibulocephalic and oculocephalic reflexes were absent. Aplasia of the paramedian zone of the pontine tegmentum, on a familial basis, is postulated as the cause.

Adult↗