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Kirti Singh

Publications and source records attributed to Kirti Singh.

7 recordsLinked to original sources
PubMed2006

Visual field defects in epidemic dropsy.

UNLABELLED: Epidemic dropsy is a multi-system disease involving the cardiovascular, hepatic, renal, ocular and other systems. It is a toxic disease caused by the unintentional ingestion of Argemone mexicana (prickly yellow poppy) seeds as an adulterant of wheat flour or more commonly of cooking oil such as mustard oil. PURPOSE: To investigate the occurrence of visual field defects in patients suffering from epidemic dropsy glaucoma. METHODS: Visual field analysis was performed to ascertain the field defects, in patients suffering from epidemic dropsy. Group I consisted of 35 patients (69 eyes) whose intraocular pressure (IOP) was > or = 22 mmHg. Ten dropsy patients (20 eyes) with normal IOP (<22 mm Hg) formed Group II. Ten healthy unexposed volunteers (20 eyes) constituted Group III. All the patients were tested using the Armaly full field glaucoma screening test on the Humphrey field analyzer. RESULTS: Forty seven of the 69 eyes (68%) suffering from epidemic dropsy glaucoma, and 18 out of 20 (90%) eyes in dropsy patients with normal IOP, showed field defects. In the control group, 15% eyes had only nasal field defects. The difference between Group I and II was not significant (p = 0.054), though the field defects were significantly more frequent in dropsy patients as compared to the controls (p < 0.01 in either case). The results suggest that visual field defects in epidemic dropsy occur independently of the rise in intraocular pressure. Field defects were detected more frequently in patients who underwent visual field analysis early in the course of disease, as compared to those who underwent screening later on in the disease course. CONCLUSIONS: In epidemic dropsy, acute visual field defects occur independent of rise of intraocular pressure and more frequently in the early stage of the disease.

Adolescent↗
PubMed2005

Spectrum of fungal keratitis in North India.

PURPOSE: To report the epidemiologic features and laboratory results of 191 consecutive cases of fungal keratitis presenting to a tertiary level superspecialty teaching hospital of North India. METHODS: A prospective hospital-based study was carried out on 485 consecutive patients presenting with corneal ulcers to the outpatient department of Guru Nanak Eye Center, Maulana Azad Medical College, New Delhi, from January 1999 to June 2001. The sociodemographic data, predisposing risk factors, clinical details, prior treatment modalities, laboratory results, and visual outcomes were analyzed. RESULTS: Diagnosis of mycotic keratitis was established in 191 (39%) out of the total study group of 485 cases. Direct microscopic examination of KOH mounts and Gram-stained smears revealed presence of fungal elements in the corneal scrapings in 119 (62.3%) and 114 (60%) of the subsequently fungal culture-positive cases, respectively. Men (68%) were more commonly affected by fungal keratitis than women (32%). Young adults 31-40 years of age were the most common age group to be involved (36%). Predisposing risk factors were noted in 79%, with corneal trauma 42%, contact lens wear 25%, and topical corticosteroids in 21% patients. The spectrum of fungi isolated were Aspergillus species in 78 (41%) followed by Curvularia species in 55 (29%). CONCLUSIONS: In contrast to other studies from our subcontinent, we found Aspergillus niger to be the most common fungal isolate, followed by Curvularia species in culture-proven cases of fungal keratitis. Direct microscopic examination of KOH mounts emerged as a rapid, reliable, and inexpensive diagnostic modality, with a sensitivity of 62%, which would facilitate the institution of early antifungal therapy before the culture results became available, thus proving to be sight saving.

Adolescent↗
PubMed2004

Mumps-induced corneal endotheliitis.

OBJECTIVE: To report two cases of corneal endotheliitis following mumps parotitis. METHODS: Observational case reports of two patients presenting with sudden unilateral diminution of vision while they were in the resolution phase of mumps parotitis. RESULTS: Central corneal edema with no associated epithelial involvement or iridocyclitis was confirmed on slit-lamp biomicroscopy. Specular microscopy confirmed an increased corneal thickness with corneal endothelial abnormalities. The diagnosis of mumps virus infection was established through detection of IgM antibody in serum samples of the patients using enzyme-linked immunosorbent assay (ELISA). The routine investigations for other systemic diseases were negative. CONCLUSIONS: Corneal endotheliitis as a sequela to mumps is a new reported association. Timely treatment with topical steroids led to resolution of the disease with full visual recovery without any residual symptoms or signs.

Adult↗
PubMed2003

Ocular cysticercosis--a profile.

A retrospective study was conducted on all histopathologically proven cases of ocular cysticercosis spanning a decade in a tertiary referral centre of North India. The symptomatology, presentation, complications and treatment therapies of 18 of these patients are discussed. The most common age group to be affected was 11-20 years (50%), while the most common site involved was subconjunctival (78%), followed by lid (11%). Spontaneous extrusion was documented in three cases. Medical treatment with albendazole under the cover of corticosteroids was found to be a useful adjunct to surgical excision.

Adolescent↗
PubMed2002

Cherry red spot.

Explore the source record for details and available documents.

Child↗
PubMedDate not supplied

Tuberculous osteomyelitis and optic neuritis.

This case report describes a rare instance of bilateral optic papillitis associated with histologically and bacteriologically proven tubercular osteomyelitis of the right sphenoid and temporal bone of the orbit in a 30-year-old woman. This case also highlights the usefulness of computerized axial tomography of the orbits, skull, and paranasal sinuses to evaluate optic neuritis and its pathophysiology in the event of no obvious cause or contributing systemic disease.

Adult↗