Biomedical subjects

Kheng Kooi Tan

Publications and source records attributed to Kheng Kooi Tan.

5 recordsLinked to original sources

PubMed2006

Disseminated spread of recurrent oligodendroglioma (WHO grade II).

Oligodendroglioma is a relatively uncommon primary brain tumour. The occurrence of metastatic dissemination of oligodendroglioma is rare and usually occurs in patients with anaplastic oligodendroglioma. The dissemination of WHO Grade II oligodendroglioma can occur and we report a patient with an initial diagnosis of a left temporal oligodendroglioma who presented with disseminated disease in the left temporal lobe, sellar region, medulla oblongata, both frontal lobes and ventricles more than 8 years later. Histology at dissemination showed anaplastic oligodendroglioma. Similar reports of metastatic dissemination of oligodendrogliomas reveal that the tumours may remain as WHO Grade II or may progress to anaplastic oligodendroglioma at metastasis. However, regardless of the histological grade at metastasis, the prognosis of metastatic oligodendroglioma is poor.

Humans↗

PubMed2004

C1-C2 tuberculosis: a case report.

Tuberculosis of the atlantoaxial spine is a rare condition that is often overlooked and remains a diagnostic dilemma. We report the rare case of a 56-year-old woman with cervical myelopathy secondary to a lytic lesion of C1-C2 complex with a histological diagnosis of tuberculosis.

Decompression, Surgical↗

PubMed2004

MR imaging features of pigmented villonodular synovitis of the cervical spine.

Pigmented villonodular synovitis (PVNS) is a benign proliferative disorder primarily occurring in the large joints of the appendicular skeleton such as the knee and hip joints. We present an unusual case of PVNS involving the cervical spine in an adult. MR imaging showed an enhancing mass lesion arising from the posterior elements of the cervical spine and hyperintensity on the T2-weighted images, without evidence of T2 susceptibility effects. Gross total excision of the tumor was performed, and the diagnosis was established by histopathology.

Adult↗

PubMed2004

Spinal schwannoma with acute subarachnoid hemorrhage: a diagnostic challenge.

We report a case of spinal intradural schwannoma presenting with intracranial subarachnoid hemorrhage. Cerebral angiography studies were negative, but MR imaging of the spine revealed a large hemorrhagic tumor in the thoraco-lumbar junction. The tumor was misdiagnosed as ependymoma of the conus medullaris. This case illustrates the importance of a high index of suspicion for spinal disease in angiographically-negative subarachnoid hemorrhage and pitfalls in MR diagnosis of thoraco-lumbar tumors.

Acute Disease↗

PubMed2002

Spinal epidural haematoma: MRI-aided diagnosis.

Spinal epidural haematoma is a rare cause of spinal cord compression. It is most commonly attributed to trauma and coagulation disorders. We report a case of a 64 year-old man with thrombocytopaenia who presented with a traumatic epidural haematoma who p resented with right hemiparesis which progressed to complete tetraplegia. MR of the cervical spine showed an epidural collection on the posterior aspect of the cord throughout the cervical spine. The patient underwent C1-C7 laminectomy and decompression. Postoperatively, the patient has improved gradually and has power of grade 3 (Medical Research Council classification of power) in all 4 limbs at 2-month follow-up. MRI is an important modality in the early diagnosis of spinal epidural haematomas and can facilitate emergent decompressive surgery which offers the best chance of neurological improvement.

Decompression, Surgical↗