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Biomedical subjects

Kh Dimitrov

Publications and source records attributed to Kh Dimitrov.

8 recordsLinked to original sources
PubMed1986

[Immunological activity of the blood sera from cattle with chronic mycotoxicosis].

Attempts were made to disclose and reproduce the immunologic activity of the blood sera of cows, aborted fetuses, and newborn calves in feeding the cows with feeds acted upon by small amounts of toxic moulds. Studied were blood samples of cows in advanced pregnancy or such that had freshly calved, of cows with liver dystrophy, and of newborn calves with toxic dyspepsia. The methods of immunodiffusion and immunoelectrophoresis were employed. It was found that in continuous feeding with mould-affected forages the toxins that gained access into the body attacked chiefly the liver. Along with other changes it induced the release of a complex antigen that was likely to bear the character of both the toxin and the liver proteins. It is believed that the process of building up of specific immune defense against mycotoxins is more complex and continuous. Thus, the immunity obtained is not so effective as in the case of microbial infections.

Abortion, Veterinary↗
PubMed1984

[Hemorrhagic septicemia in rainbow trout due to Yersinia ruckeri sp. nov].

Bacterial hemorrhagic septicemia in rainbow trout is reported for the first time in this country, with Yersinia ruckeri as causative agent. The identification of the isolated strains was carried out on the basis of morphologic, cultural, and biochemical properties. Described are the morphologic changes, giving some epizootiologic data. Stated is the employment of an immunochemical method for differential diagnosis, based on changes that take place in the plasmal lipoproteins of diseased trouts. It has been found that the immunoelectrophoresis of sera of trouts infected with Yersinia ruckeri, using rabbit antisera against trout plasmal proteins reveals only traces of the molecularly destroyed alfa- and beta-lipoproteins.

Animals↗
PubMed1981

[Effect of therapeutic agents on the antibody titer and allergic reaction in fowl typhoid-pullorum disease].

Studies were carried out on the effect of furazolidon, spectam, Esb-3 and altabactin on the production of agglutinins and the initiation and development of an allergic response in chickens affected with pullorum disease. It was found that these preparations, when used three times at intervals of 20 days, in the course of 10 days each time at the respective therapeutic rates led to the decrease in the titer of agglutinins in the treated birds as early as the tenth day from the beginning of treatment. This trend remained unchanged during the whole period of treatment. Under the same experimental conditions no inhibition of the allergic reaction in the diseased birds against the lipopolysaccharide allergen of Salmonella gallinarum-pullorum was established.

Agglutination Tests↗
PubMed1981

[Clinical use of sequential ultrafiltration with chronic hemodialysis patients].

Twenty one sequential ultrafiltration dialysis were performed to 14 patients with chronic hemodialysis, with a duration of the dialysis treatment from 2 months to 5 years. Dry ultrafiltration--2.1-5.2 litres filtrate was obtained within 90 minutes. The sequential dialysis has numerous advantages over the usual hemodialysis. Apart from the good tolerance of the patients with overweight, some other indications for its performance was stressed upon in the paper, namely: cardiac asthma, arterial hypertension difficult to correct by hemodialysis and drugs, osteodystrophia, itching during dialysis and after it, vomiting and headache during dialysis and in-between dialysis periods, pains in the legs. The patients tolerated the procedure without any complaints.

Acid-Base Equilibrium↗
PubMed1980

[Comparison of the diagnostic indices in poultry treated against fowl typhoid pullorum].

A study was carried out on the influence of the treatment with furasolidon and altabactin, alone and in combination with spectam and Esb3, in naturally infected and chronically suffering from typhus-puporosis fowls. It was proved that the treatment leads to a clinical but not to a epizootological recovery. It was also proved that the treatment of fowls against typhus-pulorosis, did not have any effect on the sensitivity, the specificity and the detectability of the allergic reaction, whereas the diagnostic value of the serological reaction always diminished. With all the fowls treated, characteristic pathohistological changes were detected, typical of typhus-pulorosis, which make more complete the results of the serological, the allergic and the bacteriological studies, and contributed to the detection of chronically ill fowls.

Animal Feed↗