Search PubMed⌕ Search

Biomedical subjects

Kenneth J Sher

Publications and source records attributed to Kenneth J Sher.

At least 37 records · Page 2Linked to original sources
PubMed2005

Strategic control and medial frontal negativity: beyond errors and response conflict.

Errors in timed choice tasks typically produce an error-related negativity (ERN) in the event-related potential (ERP). The error specificity of the ERN has been challenged by studies showing a correct response negativity (CRN). Forty-five participants engaged in a flanker task in which both compatibility between flankers and target and the probability of compatible flankers were manipulated. Correct responses elicited a CRN, the amplitude of which increased with the degree of mismatch between the presence of conflict and conflict probability, even on low-conflict (compatible) trials. The fronto-central N2 component was larger on high-conflict (incompatible) correct response trials. However, in contrast to some recent accounts, this N2 was largest for highly probable stimuli. These findings suggest revision to models of the effects of conflict on response-related negativity to account for strategic adjustments made in preparation for the response.

Adult↗
PubMed2005

Borderline personality features predict alcohol use problems.

This study assessed the relation between BPD features and problems associated with alcohol use 2 years later in young adults. Approximately 5,000 nonclinical young adults were screened for BPD features, and two cohorts of participants completed the laboratory phase of the study at Time 1 (total N = 421) and then again 2 years later at Time 2 (total N = 356). Measures included self-report and interview-based assessments of personality disorders, psychopathology in biological parents, Axis I psychopathology, and alcohol use problems. BPD features were found to significantly predict alcohol use problems 2 years later after controlling for parents' substance use disorders, Axis I psycho-pathology (including alcohol abuse/dependence), and non-BPD personality disorders. In addition, the BPD subscale that assesses impulsivity was found to be significantly associated with alcohol use problems once all predictors were entered into the model.

Adult↗
PubMed2004

Relation of attachment style to family history of alcoholism and alcohol use disorders in early adulthood.

The present study examined the association between paternal alcoholism and attachment style in early adulthood and sought to determine whether attachment style might, at least partially, mediate intergenerational risk for alcoholism. The current report focuses on the cross-sectional relation between family history (FH) of alcoholism, attachment styles, and alcohol use disorders (AUD) when cohort members were, on average, 29 years old (N = 369; 46% male; 51% FH+). Results indicated that FH+ participants were more likely to have insecure attachment, characterized by fearful-avoidant and dismissed-avoidant styles. Additionally, fearful-avoidant and dismissed-avoidant attachment styles were related to the presence of an AUD even after controlling for sex and FH (P < 0.05). There was little evidence, however, that attachment style mediated the relation between paternal alcoholism and AUD in offspring; the FH-AUD association was only negligibly reduced when the effect of attachment style was controlled. Our findings suggest that insecure attachment style is a risk factor for AUD, independent of familial risk for alcoholism.

Adult↗
PubMed2004

Trajectories of dynamic predictors of disorder: their meanings and implications.

Developmental psychopathologists are increasingly focused on characterizing heterogeneity of trajectories of psychological disorders across the life course (e.g., developmentally limited vs. chronic forms of disorder). Although the developmental significance of trajectories has been highlighted, there has been little attention to relations between trajectories and their etiologically and clinically relevant time-varying covariates (dynamic predictors). Depending upon the functional relation between a disorder and a dynamic predictor, we expect to see different trajectories of dynamic predictors. Thus, we propose a taxonomy of trajectories of dynamic predictors of course of disorder and provide an initial investigation into its validity. Using a mixed-gender, high-risk sample of young adults followed over 7 years, we identified dynamic predictors that covary with the course of alcohol use disorder (AUD). Based on a logically derived classification to facilitate interpretation of findings, three comparison groups were examined: persons whose AUD "remitted" (n = 33), those with a chronic AUD (n = 29), and nondiagnosers (n = 274). We hypothesized seven patterns of dynamic prediction (stable vulnerability indicators, course trackers, deterioration markers, developmentally specific variables, developmental lag markers, course-referenced variables, and recovery behaviors) and found evidence for five of them. The interpretation of markers of risk for development and course of AUDs and their implications for prevention, early intervention and formal/self-change treatments are discussed.

Adult↗
PubMed2004

Do college students drink more than their non-college-attending peers? Evidence from a population-based longitudinal female twin study.

The association of college attendance with alcohol use and alcohol use disorders was examined in a population-based young adult female twin sample identified from a systematic search of birth records. College-attending women consumed a larger overall volume of alcohol than did their non-college-attending peers, but they were not more likely to be diagnosed with an alcohol use disorder. Significant associations between college attendance and alcohol involvement were probed using 3 different complementary research designs: multivariate cross-sectional analyses, longitudinal analyses of the precollege and college years, and cotwin-control analyses of twin pairs discordant for attending college. Although demographic and lifestyle characteristics accounted for most or all of the association between college attendance and alcohol involvement, there was 1 aspect of drinking behavior, occasionally consuming large quantities of alcohol, that remained significantly associated with college attendance even after controlling for these characteristics or for genetic and family background factors. These results are consistent with the conclusion that some aspect of the college experience may be an important environmental risk factor for this pattern of drinking among young adults.

Adult↗
PubMed2004

Alcohol, tobacco, and drug use disorders and personality disorder symptoms.

In a nonclinical sample of 395 young adults, the authors evaluated the relations between major personality traits, Diagnostic and Statistical Manual of Mental Disorders (4th ed.; DSM-IV; American Psychiatric Association, 1994) personality disorder symptoms, and DSM-IV alcohol use disorders (AUDs). Consistent with previous findings, traits related to disinhibition and negative affectivity were consistently associated with AUDs, as were Cluster B personality disorder symptoms (especially antisocial and borderline disorder symptoms). Multivariate analyses revealed that Cluster B symptoms were significantly associated with AUDs above and beyond what was accounted for by personality traits. Further, the authors found differential patterns of relations between other substance use disorders (SUDs; i.e., tobacco dependence and drug use diagnoses) and personality disorder symptoms. Overall, these results suggest that personality disorder symptoms predict unique variance in SUDs that reflect maladaptive aspects of personality traits.

Adolescent↗
PubMed2004

Collecting longitudinal data through childhood, adolescence, and young adulthood: methodological challenges.

This article presents the proceedings of a workshop at the 2003 Research Society on Alcoholism meeting in Fort Lauderdale, Florida. The organizers and chairs were Vivian Faden and Nancy Day. The presentations were (1) Lessons Learned From the Lives Across Time Longitudinal Study, by Michael Windle and Rebecca Windle; (2) Methodological Issues in Longitudinal Surveys With Children and Adolescents, by Joel Grube; (3) The Pittsburgh ADHD Longitudinal Study: Methodological and Conceptual Challenges, by Brooke Molina, William Pelham, Elizabeth Gnagy, and Tracey Wilson; and (4) Lessons learned in Conducting Longitudinal Research on Alcohol Involvement: If Only I Had Known Before Hand! by Kristina Jackson and Kenneth Sher.

Adolescent↗
PubMed2004

The role of behavioral undercontrol in the relation between alcohol use and partner aggression.

OBJECTIVE: Recent studies suggest that pre-existing aggressive personality traits moderate the relationship between alcohol use and intimate partner violence. The current study extends this literature by examining the relationship between behavioral undercontrol, patterns of alcohol use and relationship aggression in the context of a large, high-risk sample. METHOD: Participants were drawn from a cohort of 489 young adults taking part in an 11-year longitudinal study. Participants completed self-report measures of behavioral undercontrol, alcohol use and relationship aggression at Years 7 and 11 of the study when most were 25 and 29 years old, respectively. RESULTS: Results revealed that a composite measure of behavioral undercontrol predicted relationship aggression cross-sectionally. Although the composite behavioral undercontrol measure did not interact with alcohol use to predict relationship aggression, one of the measures that comprised the composite (the Agreeableness scale from the Neuroticism-Extraversion-Openness to Experience Five Factor Inventory) did. Longitudinal analyses revealed that behavioral undercontrol measured at Year 7 did not predict relationship aggression measured at Year 11. CONCLUSIONS: Results suggest that behavioral undercontrol is related to relationship aggression outside the laboratory. Individuals with low levels of agreeableness also appear to be at heightened risk for intoxicated aggression. Potential explanations for these findings are discussed.

Aggression↗
PubMed2003

Alcohol and tobacco use disorders in a general population: short-term and long-term associations from the St. Louis epidemiological catchment area study.

BACKGROUND: Although research using clinical and convenience samples has shown alcohol use disorders (AUD) to be highly comorbid with tobacco dependence (TD), little work has examined this association prospectively using population-based data. The AUD-TD association was prospectively examined using data from the St. Louis Epidemiological Catchment Area (ECA) Study and its 1-year follow-up as well as from a 16-year follow-up on a subsample of ECA data. METHOD: Respondents were 3004 (2564, 85%, at Wave 2) participants in the St. Louis household ECA sample, including 444 participants at Year 16 follow-up. At baseline, the sample was predominately White (58%; 38% Black), female (60%), and 44.3 years. Past-year AUD and TD were diagnosed at all waves according to DSM-III criteria. RESULTS: AUDs and TDs were cross-sectionally associated at Years 1, 2, and 16. Controlling for demographics, Year 1 TD prospectively predicted Year 2 AUD, and Year 1 AUD prospectively predicted Year 16 TD. We found evidence for prediction of onset and persistence of both AUD and TD at short-term but not long-term follow-up. Prospective findings were reduced and no longer reached significance when concurrent diagnoses at follow-up were included in the regression models. CONCLUSIONS: We observed short-term and long-term associations between AUD and TD. These associations were mediated through concurrent diagnoses with the other substance use disorder.

Adult↗
PubMed2003

Effects of alcohol consumption and alcohol susceptibility on cognition: a psychophysiological examination.

The present study sought to examine acute effects of alcohol on cognitive processing and performance within the context of two prominent theories of alcohol's effects; namely, that alcohol restricts the focus of attention (e.g. Steele and Josephs, 1990. Journal of Abnormal Psychology, 97, 196-205) and that alcohol impairs response inhibition (e.g. Fillmore and Vogel-Sprott, 1999. Experimental and Clinical Psychopharmacology, 7, 49-55; Fillmore and Vogel-Sprott, 2000. Journal of Studies on Alcohol, 61, 239-246). Forty-five participants were randomly assigned to receive either a placebo level of alcohol (0.04 g/kg), a moderate dose (0.40 g/kg), or a higher dose (0.80 g/kg). Brain electrical activity (ERPs) and behavioral responses (reaction time and accuracy) were measured while participants performed a modified flanker task, in which a target letter was flanked by response-compatible or response-incompatible letters. Analyses of behavioral data showed that alcohol increased response competition in accuracy but not response times, suggesting that alcohol influences response selection more than attentional processes per se. This finding is in-line with predictions derived from the response inhibition model. ERP latency data provided mixed support for both models. ERP amplitude data showed that the high dose of alcohol primarily influenced a mostly frontal negativity in the ERP, present on both correct and incorrect response trials. Differences in self-reported susceptibility to alcohol were most evident in the amplitude of the P3 component. Findings are discussed in terms of the differential effects of acute dose and susceptibility on information processing.

Adult↗
PubMed2003

The natural history of problem gambling from age 18 to 29.

Aggregate-level prevalences and individual-level developmental trajectories of untreated problem gambling were examined in an 11-year, 4-wave longitudinal study spanning the adolescent through young adult years. The past-year prevalences, 3-4 year incidences, and lifetime prevalences of problem gambling from adolescence through young adulthood were relatively stable at 2%-3%, 1%-2%, and 3%-5%, respectively. Despite the stability of the prevalences at the aggregate level, problem gambling appeared to be more transitory and episodic than enduring and chronic at the individual level. The present study is consistent with the limited evidence available on the natural history of problem gambling in the community in suggesting that natural recovery may be the rule rather than the exception.

Adolescent↗
PubMed2003

Alcohol use disorders and psychological distress: a prospective state-trait analysis.

The present study examined the association between alcohol use disorders (AUDs) and psychological distress over an 11-year period using a sample of 378 young adults (46% men, 54% women: baseline age = 18.5; 51% with paternal history of alcoholism). The authors examined this relation using a state-trait model, which decomposes variance in a given construct into a general traitlike factor that spans measurement occasion and more situational, occasion-specific variability. Trait AUD and trait distress were correlated (r =.43), suggesting that the tendency to meet criteria for an AUD is associated with the tendency to experience psychological distress. Much of this association was due to 3rd variables (primarily neuroticism but also childhood stressors and behavioral undercontrol), supporting a common 3rd-variable influence model of comorbidity.

Adolescent↗
PubMed2003

Changes in heavy drinking over the third decade of life as a function of collegiate fraternity and sorority involvement: a prospective, multilevel analysis.

Although affiliation with a fraternity or sorority is an important risk factor for heavy drinking, recent research indicates that this risk may be limited to the college years. Random coefficient growth modeling was used to track changes in patterns of heavy drinking over the course of 11 years as a function of gender and collegiate Greek involvement (N=318). Overall, greater cumulative exposure to the Greek system led to increased heavy drinking during the college years, particularly among men. Shortly after leaving college, heavy drinking levels dropped markedly and remained low through approximately age 30. Inclusion of peer alcohol use norms in the model reduced the influence of Greek involvement. Implications for models of heavy drinking and health risks are discussed.

Adolescent↗
PubMed2003

Reliability of self-reported age of substance involvement onset.

The authors investigated the reliability of self-reported age of onset (AO) for alcohol, tobacco (cigarette), and illicit drug involvement. Participants were 410 young adults taking part in an 11-year longitudinal study. A moderate degree of reliability was found for the 3 substances. Despite this level of stability, results illustrate a tendency for reported AOs to increase over time. The trend is more salient for participants who reported younger AOs at the initial assessment. Findings also indicate that, for alcohol and tobacco, more individuals were classified as early onset based on Year 1 compared with Year 11 reports. Despite these systematic changes, at least for alcohol and illicit drugs, age at which onset was assessed did not moderate the association between AO and substance-related outcomes.

Adolescent↗
PubMed2003

Changing expectancies: cognitive mechanisms and context effects.

This article presents the proceedings of a symposium at the 2002 RSA Meeting in San Francisco, organized by Reinout W. Wiers and Mark D. Wood. The symposium combined two topics of recent interest in studies of alcohol expectancies: cognitive mechanisms in expectancy challenge studies, and context-related changes of expectancies. With increasing recognition of the substantial role played by alcohol expectancies in drinking, investigators have begun to develop and evaluate expectancy challenge procedures as a potentially promising new prevention strategy. The two major issues addressed in the symposium were whether expectancy challenges result in changes in expectancies that mediate intervention (outcome relations), and the influence of simulated bar environments ("bar labs," in which challenges are usually done) on expectancies. The presentations were (1) An introduction, by Jack Darkes; (2) Investigating the utility of alcohol expectancy challenge with heavy drinking college students, by Mark D. Wood; (3) Effects of an expectancy challenge on implicit and explicit expectancies and drinking, by Reinout W. Wiers; (4) Effects of graphic feedback and simulated bar assessments on alcohol expectancies and consumption, by William R. Corbin; (5) Implicit alcohol associations and context, by Barry T Jones; and (6) A discussion by Kenneth J. Sher, who pointed out that it is important not only to study changes of expectancies in the paradigm of an expectancy challenge but also to consider the role of changing expectancies in natural development and in treatments not explicitly aimed at changing expectancies.

Alcohol Drinking↗
PubMed2003

Alcohol involvement and developmental task completion during young adulthood.

OBJECTIVE: Relations among young adult alcohol use disorders (AUDs), preadulthood variables (gender, family history of alcoholism, childhood stressors, high-school class rank, religious involvement, neuroticism, extraversion, psychoticism) and young adult developmental tasks (baccalaureate degree completion, full-time employment, marriage) were evaluated. METHOD: Participants were 424 first-time college students (228 women) who were 18-20 years old; approximately half had a history of paternal alcoholism. Participants were assessed on five occasions over 7 years (Years 1, 2, 3, 4 and 7). RESULTS: Structural equation modeling results suggest preadulthood variables were more salient predictors of developmental tasks than AUD diagnoses, with the majority of effects due to apparent selection processes. In addition, marriage protected against later AUD diagnosis at Year 7. CONCLUSIONS: Findings highlight the importance of prospective multivariate models that specify potential selection, causation, socialization and reciprocal effects in order to fully examine complex relations among variables, including alcohol involvement, during major life-transition periods.

Adolescent↗