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Biomedical subjects

Kendra Schwartz

Publications and source records attributed to Kendra Schwartz.

33 records · Page 2Linked to original sources
PubMed2004

Pharyngitis clinical prediction rules: effect of interobserver agreement: a MetroNet study.

OBJECTIVE: Pharyngitis clinical prediction rules improve Group A beta-hemolytic streptococcus (GABHS) diagnosis and decrease unnecessary antibiotic use, yet few studies have addressed clinician variability in assessment of sore throat signs and symptoms. STUDY DESIGN AND SETTING: We conducted a cross-sectional study in which two clinicians examined each of 200 adult sore throat patients. Each patient had a rapid GABHS antigen test. Clinicians were blinded to each other's assessment and to the rapid antigen result. Interobserver agreement was estimated using a kappa coefficient. Effect of agreement on sensitivity, specificity, and hypothetic rapid antigen testing and antibiotic prescribing was determined for two clinical prediction rules. RESULTS: We found moderate inter-rater reliability on sore throat history and physical assessments. Clinician agreement was associated with significantly fewer hypothetic rapid antigen tests performed. CONCLUSION: Interobserver agreement enhances the utility of pharyngitis clinical prediction rules. Medical school and residency training should focus on correct assessment of history and physical examination components used in GABHS clinical prediction rules. Correct assessment will result in less GABHS testing and antibiotic prescriptions for sore throat patients.

Acute Disease↗
PubMed2003

Lactation mastitis.

Explore the source record for details and available documents.

Anti-Bacterial Agents↗
PubMed2003

Duration of breastfeeding, daycare, and physician visits among infants 6 months and younger.

PURPOSE: To describe the association between duration of breastfeeding and an illness requiring a visit to a health care provider within the past 30 days (IRHP) among infants </= 6 months. METHODS: Participants were breastfeeding women who delivered at a birthing center in suburban Detroit, Michigan and women employed by a company in Omaha, Nebraska. Subjects were interviewed by telephone at 3,6,9, and 12 weeks postpartum and by mailed questionnaire at 6 months postpartum. RESULTS: Of the 674 breastfeeding women, 233 (34.5%) reported an IRHP. An IRHP was more likely among infants attending daycare (RR = 1.60; 95% CI 1.30, 1.96). There was an interaction between duration of breastfeeding, the number of children in the household, and IRHP (p < 0.0001). For firstborn children, each additional week of breastfeeding decreased the likelihood of an IRHP by 4%. An increased duration of breastfeeding was not significantly protective against an IRHP for infants living with additional children in the household. CONCLUSIONS: Breastfeeding offers protection against an IRHP among firstborn children. Having additional children in the household or attending daycare outside of the home may diminish these benefits.

Adolescent↗
PubMed2003

Weaning practices among breastfeeding women who weaned prior to six months postpartum.

We describe weaning practices among 222 breastfeeding mothers who weaned their babies < or = 6 months postpartum. After initiating weaning, one fourth of participants weaned within 2 days and three fourths by 14 days (range, 0-90 days). Shorter weaning duration was associated with earlier ages at weaning. After adjustment for time of weaning, women who returned to work were more likely to take > 3 days to wean (odds ratio = 2.98; 95% confidence interval = 1.53, 5.79). Women weaning in < or = 3 days versus 4 or more days were more likely to report binding their breasts (31% or 15%, P = .007) or using ice packs (9% vs 1%, P = .0006) and were more likely to report feeling happier since weaning (23% vs 9%, P = .005). Most women weaning < or = 6 months postpartum took 4 or more days to wean their baby. Experience and anecdote have been the norm in informing weaning practices. This study is a first step toward more rigorous evaluation.

Adolescent↗
PubMed2003

Are ionized wrist bracelets better than placebo for musculoskeletal pain?

As a result of a profound placebo effect, this study showed that Q-Ray ionized wrist bracelets were not superior to placebo bracelets in self-reported pain improvement among patients with musculoskeletal pain. Like many other studies involving the treatment of pain, the perception that the treatment would work profoundly improved its effectiveness. While the bracelet did not work better than placebo, many patients may experience less pain if they purchase and use it.

Complementary Therapies↗
PubMed2003

Use of on-line evidence-based resources at the point of care.

BACKGROUND AND OBJECTIVES: The utility of on-line evidence-based summary databases for answering clinical questions at the point of care is not well understood. Our objectives were to determine if family physician faculty could answer their questions using on-line resources and the proportion of answers that influenced patient care. METHODS: This was a prospective study in which clinical faculty in an urban residency training office recorded their clinical questions and their search results. RESULTS: Faculty asked 92 questions. Therapy, prognosis, and epidemiology questions were the most common types of inquiries. Fifty-four percent of the questions were fully or partially answered by use of an on-line resource; obtaining an answer required 5-10 minutes of searching. Physicians reported that 62% of the obtained answers modified their opinion, influenced the care of the current patient 56% of the time, and would affect the care of future patients 70% of the time. Slow Internet connection and interruptions were the most frequent barriers reported. DISCUSSION: Practicing physicians inexperienced in the use of on-line evidence-based resources answered a proportion of their clinical questions that was comparable to reports of more-experienced searchers; however, the time required to find answers limits the practical use of these databases during patient care time. On-line summary databases such as those used in this study show promise in providing answers that influence care during the patient's visit. With faster Internet connection (or handheld devices) and improved navigability, such resources have the potential to optimize health care in the primary care setting.

Clinical Competence↗
PubMed2003

Topical ophthalmic NSAIDs reduce pain faster than placebo.

Topical ophthalmic nonsteroidal anti-inflammatory drugs (NSAIDs) relieve the pain of uncomplicated acute corneal abrasions faster than placebo eyedrops. The pain relief is small; whether the pain relief difference would be noticed by patients and how it compares with oral analgesics is unknown. Given the cost of topical NSAIDs, they are most useful for a select patient population: those who must return to work immediately, and those for whom opioid analgesia-induced sedation is intolerable.

Comment↗
PubMed2002

Complications from treatment for prostate carcinoma among men in the Detroit area.

BACKGROUND: Aggressive treatment of early stage prostate carcinoma (PC) is limited primarily to two modalities: radical prostatectomy (RP) and external beam radiation therapy (RT). The authors conducted a population-based study of Detroit area men with localized PC to determine the outcome of bowel, urinary, and sexual function after aggressive treatment. METHODS: Men with PC were identified through the Metropolitan Detroit Cancer Surveillance System, a member of the National Cancer Institute Surveillance, Epidemiology, and End Results Program. Patients participated in interviews about their pretreatment bowel, urinary, and sexual function approximately 9 months after treatment. The same men were asked identical questions about their function an average of 2 years after treatment. Treatment outcomes were compared for men who underwent RP and men who received RT. RESULTS: Of 501 men, 398 (79.4%) participated in both interviews, 304 of whom (76.4%) had localized PC and had been treated at least 1 year previously (median, 688 days). One hundred thirty men underwent RP, and 115 men received RT. The proportion of men in the RP group who reported an increase in incontinence symptoms was significant (53.8% compared with 19.2% in the RT group; P < 0.001). Men in the RT group reported increased loose stools between the pretreatment and post-treatment interviews (5.2% vs. 29.6%; P < 0.001). Men in both the RT group and the RP group reported increases in impotence from 40% to > 75% (P < 0.001 for both). Men in the RT group were 3.6 times more likely to have bowel incontinence compared with men in the RP group (odds ratio [OR], 3.61; 95% confidence interval [95% CI], 1.54-8.47). Urinary incontinence (OR, 2.87; 95% CI, 1.52-5.44) and erection difficulty (OR, 3.98; 95% CI, 1.35-11.70) were more likely among men in the RP group. CONCLUSIONS: Although patients may have recalled their baseline function as better than it was, the current results are consistent with other population-based studies of treatment outcomes among men with localized PC. They indicate that the side effects associated with treatment are greater than those based on case series. Physicians and patients should be aware of these population-based outcomes and should use them as part of the decision-making process regarding the treatment options for men with PC.

Aged↗
PubMed2002

Lactation mastitis: occurrence and medical management among 946 breastfeeding women in the United States.

In 1994-1998, the authors followed 946 breastfeeding women from Michigan and Nebraska for the first 3 months postpartum or until they stopped breastfeeding to describe mastitis incidence, mastitis treatment, and any associations between mastitis occurrence and hypothesized host characteristics and behaviors. Participants were interviewed by telephone at 3, 6, 9, and 12 weeks postpartum or until they ceased breastfeeding. A total of 9.5% reported provider-diagnosed lactation mastitis at least once during the 12-week period, with 64% diagnosed via telephone. After adjustment in a logistic regression model, history of mastitis with a previous child (odds ratio (OR) = 4.0, 95% confidence interval (CI): 2.64, 6.11), cracks and nipple sores in the same week as mastitis (OR = 3.4, 95% CI: 2.04, 5.51), using an antifungal nipple cream (presumably for nipple thrush) in the same 3-week interval as mastitis (OR = 3.4, 95% CI: 1.37, 8.54), and (for women with no prior mastitis history) using a manual breast pump (OR = 3.3, 95% CI: 1.92, 5.62) strongly predicted mastitis. Feeding fewer than 10 times per day was protective regardless of whether or not feeding frequency in the same week or the week before mastitis was included in the model (for the same week: 7-9 times: OR = 0.6, 95% CI: 0.41, 1.01; < or =6 times: OR = 0.4, 95% CI: 0.19, 0.82). Duration of feeding was not associated with mastitis risk.

Adult↗
PubMed2002

Factors associated with weaning in the first 3 months postpartum.

OBJECTIVE: To determine the demographic, behavioral, and clinical factors associated with breastfeeding termination in the first 12 weeks postpartum. STUDY DESIGN: This was a prospective cohort study. POPULATION: Breastfeeding women in Michigan and Nebraska were interviewed by telephone at 3, 6, 9, and 12 weeks postpartum or until breastfeeding termination. OUTCOMES MEASURED: We measured associations of demographic, clinical, and breastfeeding variables with weaning during the first 12 weeks postpartum. RESULTS: A total of 946 women participated; 75% breastfed until 12 weeks. Women older than 30 years and women with at least a bachelor's degree were more likely to continue breastfeeding in any given week. Mastitis, breast or nipple pain, bottle use, and milk expression in the first 3 weeks were all associated with termination. Beyond 3 weeks, women who expressed breast milk were 75% less likely to discontinue breastfeeding than women who did not. Women who used a bottle for some feedings during weeks 4 to 12 were 98% less likely to discontinue breastfeeding than women who did not use a bottle. "Not enough milk" was the most common reason given for termination in weeks 1 through 3 (37%) and weeks 4 through 6 (35%); "return to work" was the most common reason given in weeks 7 through 9 (53%) and weeks 10 through 12 (58%). CONCLUSIONS: Younger women and less educated women need additional support in their breastfeeding efforts. Counseling and assistance should be provided to women with pain and mastitis. Exclusive breastfeeding for the first 3 weeks should be recommended. After the first 3 weeks, bottles and manual expression are not associated with weaning and may improve the likelihood of continuing breastfeeding, at least until 12 weeks.

Breast Feeding↗