Biomedical subjects

Kaveh Manavi

Publications and source records attributed to Kaveh Manavi.

4 recordsLinked to original sources

PubMed2006

A review on infection with Chlamydia trachomatis.

Infection with Chlamydia trachomatis accounts for the most common bacterial sexually transmitted infection in the UK. Men between 20 and 24 years and women between 16 and 19 years have the highest prevalence of chlamydial infection. Because the majority of women with chlamydial infection are asymptomatic, a proportion remains untreated and eventually develops pelvic inflammatory disease (PID). PID can result in ectopic pregnancy, infertility and chronic pelvic pain. Screening for chlamydial infection might reduce the incidence of complications of PID. The advent of nucleic acid amplification tests and single-dose therapy for chlamydial infection has made home testing and easy treatment possible.

Adolescent↗

PubMed2006

A review on infection with human immunodeficiency virus.

Management of infection with human immunodeficiency virus (HIV) improved dramatically during the 1990s. The advent of high-performance quantitative HIV assays and highly active antiretroviral therapy were the two most important developments in HIV medicine. As a result, HIV mortality and morbidity have reduced significantly, although a proportion of HIV-infected patients are still diagnosed late. Management of HIV during pregnancy has also improved so that vertical transmission is now limited to less than 2% of all cases. Knowledge of the different stages of HIV infection enables optimal timing of start of antiretroviral therapy. Routine offering of HIV testing might also reduce the number of patients diagnosed with immunodeficiency. Better knowledge of the life cycle of HIV has made it possible to design new classes of antiretroviral drugs. The new drugs, however, pose new challenges as they might have long-term side effects. In addition, their interactions with other antiretroviral drugs might not be favourable.

Acquired Immunodeficiency Syndrome↗

PubMed2005

HIV testing.

Explore the source record for details and available documents.

AIDS Serodiagnosis↗

PubMed2003

Sensitivity of microscopy for the rapid diagnosis of gonorrhoea in men and women and the role of gonorrhoea serovars.

Auditing the sensitivity of microscopic diagnosis of gonorrhoea is recommended by the current guidelines. A retrospective study was performed of 596 cases of positive cultures for Neisseria gonorrhoeae in modified New York City culture (MNYC) media diagnosed from 1995 to 1999. The sensitivity of the cervical slides in women was 51% while in men who have sex with men (MSM) the sensitivity of urethral and rectal slides were 89% and 54% respectively. The sensitivity of urethral slides in heterosexual men was 84%. Neisseria serovar 1B02 among MSM and serovar 1B31 among women were mostly undiagnosed with microscopy. Serovars 1A05, 1A21, B08 among heterosexual men were exclusively associated with negative microscopy. Microscopy is important in the rapid detection and treatment of gonorrhoea. Infections with certain serovars are less likely to be detected by microscopy; making them more likely to spread within the community. Culture from different ano-genital sites is essential to maximize detection of gonorrhoea in all patients.

Adult↗