Biomedical subjects

Kathryn J Saunders

Publications and source records attributed to Kathryn J Saunders.

5 recordsLinked to original sources

PubMed2006

Accommodative dysfunction in children with cerebral palsy: a population-based study.

PURPOSE: To determine the prevalence, nature, and degree of accommodative dysfunction among children with different types and severities of cerebral palsy (CP) in Northern Ireland. METHODS: Ninety subjects with CP (aged 4-15 years) were recruited through the Northern Ireland CP Register (NICPR). Modified Nott dynamic retinoscopy was used to measure lag and lead of accommodation at three test distances: 25 cm (4 D), 16.7 cm (6 D), and 10 cm (10 D) with the distance correction in place. Accommodative function was also assessed in an age-matched control group (n = 125) for comparison. Each subject's neurologic status was derived from the NICPR. RESULTS: Children with CP demonstrate significantly reduced accommodative responses compared with their neurologically normal peers. Of the subjects with CP, 57.6% demonstrated an accommodative lag outside normal limits at one or more distances. Reduced accommodative responses were significantly associated with more severe motor and intellectual impairments (ANOVA P = 0.001, P < 0.01, respectively). CONCLUSIONS: Brain injury such as that present in CP has a significant impact on accommodative function. These findings have implications for the optometric care of children with CP and inform our understanding of the impact of early brain injury on visual development.

Accommodation, Ocular↗

PubMed2006

Intertrial sources of stimulus control and delayed matching-to-sample performance in humans.

Two experiments compared delayed matching-to-sample (DMTS) accuracy under 2 procedures in adults with mental retardation. In the trial-unique procedure, every trial in a session contained different stimuli. Thus, comparison stimuli that were correct on one trial were never incorrect on other trials in that session (or vice versa). In the 2-sample DMTS procedure, the same 2 comparison stimuli were presented on each trial, and their function changed quasi-randomly across trials conditional upon the sample stimulus. Across 2 experiments, 7 of 8 subjects showed the highest overall accuracy under the trial-unique procedure, and no subject showed consistently higher accuracy under the 2-sample procedure. Negative, exponential decay functions fit to logit p values showed that this difference was due largely to the steeper delay-mediated decline in sample control for the 2-sample procedure. Stimulus-control analyses indicated that, under the 2-sample procedure, the selection of the comparison stimulus on Trial N was often controlled by the comparison stimulus selection on Trial N-1 rather than the Trial-N sample stimulus. This source of competing stimulus control is not present in trial-unique procedures. Experiment 2 manipulated intertrial interval duration. There was a small but consistent increase in accuracy as a function of intertrial interval duration under the 2-sample procedure, but not under the trial-unique procedure.

Adult↗

PubMed2004

Accommodative lag using dynamic retinoscopy: age norms for school-age children.

BACKGROUND: Nott dynamic retinoscopy (DR) is a technique that provides an objective, rapid assessment of accommodative function. Presently there are no data available regarding age norms of accommodative function for school-age children using Nott DR. METHODS: Accommodative responses were assessed in a group of 125 school-age children (4 to 15 years of age) using Nott DR. A range of accommodative demands was included [4 D (25 cm), 6 D (16.7 cm), and 10 D (10 cm)]. All the subjects had fully corrected refractive errors and a binocular visual acuity of at least 6/6. RESULTS: Accommodative responses were assessed successfully at each distance with all the subjects (N = 125). A mean overall lag of accommodation was noted with each age group at each distance tested. Regression analysis demonstrated no significant difference in accommodative responses between age groups (p = 0.531 at 4 D, p = 0.062 at 6 D, and p = 0.883 at 10 D). Therefore, results for all the age categories were grouped together to produce a table of normal ranges of accommodation for children aged 4 to 15 years for the three stimuli demands. The mean lag of accommodation was found to be 0.30 +/- 0.39 D at 4 D, 0.74 +/- 0.58 D at 6 D, and 2.50 +/- 1.27 D at 10 D. The normal ranges of accommodation (95% confidence limits) were 2.94 to 4.46 D at 4 D, 4.12 to 6.40 D at 6 D, and 5.02 to 10.00 D at 10 D. CONCLUSIONS: A comprehensive table has been produced detailing the mean lags and normal ranges of accommodative responses expected for school-age children when using Nott DR. These data allow practitioners and researchers to determine whether accommodative responses measured using Nott DR are within normal limits.

Accommodation, Ocular↗

PubMed2003

Recombinative generalization of within-syllable units in nonreading adults with mental retardation.

Two adults with mental retardation demonstrated the recombination of within-syllable units (onsets and rimes) using a spoken-to-printed-word matching-to-sample (MTS) procedure. Further testing with 1 participant showed comprehension of the printed words. Printed-word naming was minimal before, but greater after, comprehension tests. The findings suggest that these procedures hold promise for further basic and applied analyses of word-attack skills.

Adult↗

PubMed2003

Equivalence relations in individuals with language limitations and mental retardation.

The study of equivalence relations exhibited by individuals with mental retardation and language limitations holds the promise of providing information of both theoretical and practical significance. We reviewed the equivalence literature with this population, defined in terms of subjects having moderate, severe, or profound mental retardation. The literature includes 55 such individuals, most of whom showed positive outcomes on equivalence tests. The results to date suggest that naming skills are not necessary for positive equivalence test outcomes. Thus far, however, relatively few subjects with minimal language have been studied. Moreover, we suggest that the scientific contributions of studies in this area would be enhanced with better documentation of language skills and other subject characteristics. With recent advances in laboratory procedures for establishing the baseline performances necessary for equivalence tests, this research area is poised for rapid growth.

Discrimination, Psychological↗