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Biomedical subjects

Karen J Reynolds

Publications and source records attributed to Karen J Reynolds.

3 recordsLinked to original sources

Development and validation of a generic 3D model of the distal femur.

The development and validation of a virtual generic 3D model of the distal femur using computer graphical methods is presented. The synthesis of the generic model requires the following steps: acquisition of bony 3D morphology using standard computed tomography (CT) imaging; alignment of 3D models reconstructed from CT images with a common coordinate system; computer graphical sectioning of the models; extraction of bone contours from the image sections; combining and averaging of extracted contours; and 3D reconstruction of the averaged contours. The generic models reconstructed from the averaged contours of six cadaver femora were validated by comparing their surface geometry on a point to point basis with that of the CT reconstructed reference models. The mean errors ranged from 0.99 to 2.5 mm and were in agreement with the qualitative assessment of the models.

Aged↗

A new versatile hand dynamometer.

This paper describes the design and testing of a new hand strain-gauge based dynamometer. The design is portable and capable of measuring grip strengths from 12.5 to 800N. The dynamometer is independent of point of application of the grip force. Finite element modelling and experimental testing were used to verify the mechanical system's suitability. The dynamometer was designed for input to a PDA to allow full portability of the device.

Biomechanical Phenomena↗

The accuracy of three-dimensional reconstructions of the ovine knee: dissectional validation.

A single, complete, ovine knee was imaged using conventional MRI then dissected allowing comprehensive dimensional measurement of the intra-articular structures. A three-dimensional (3-D) computer model of the knee was generated from the MR sections. Thirty-two individual structural measures were recorded from the image output for which there was an available surgical measure for direct comparison. The results of Pearson's correlation testing show a rounded score of 1.00, suggesting an exceptional linear correlation between direct anatomical measurement and the 3-D image output. Further analysis of the data revealed an average error of measurement of 0.2mm across the 32 measures. The findings of this preliminary study suggest that 3-D reconstruction from MR data may be an appropriate, and accurate, means for making dimensional measurements of the bony and soft tissue structures of the ovine knee. It is unlikely that the measurement error would be of any great clinical significance. There is evidence in the literature to suggest that an ovine knee may be considered an acceptable model for substitution for the human knee in diagnostic assessment studies. Therefore, such findings may be considered clinically relevant in the field of human knee assessment.

Animals↗