Search PubMed⌕ Search

Biomedical subjects

K Ziaja

Publications and source records attributed to K Ziaja.

42 records · Page 3Linked to original sources
PubMedDate not supplied

Neoplastic lesions of the human liver in relation to the activity of the cytochrome P-450 dependent monooxygenase system.

We studied the activity of Mixed function oxidase (MFO) in human livers affected by cancer. We determined the content of cytochrome P-450 and b5, as well as the activity of their corresponding reductases, according to generally accepted methods. Liver fragments corresponding with a) healthy tissue, b) tissue at the cancer border and, c) cancerous tissue were collected during surgery from patients with liver cancer. We noted that the developing liver cancer decreased the level of cytochrome P-450, even by a magnitude order. The activity of its corresponding reductase was higher in cancerous than in healthy tissues. Cytochrome b5 behaved in an analogous manner, although the decrease in its content was less significant. NADH-cytochrome b5 reductase activity changes were insignificant.

Adult↗
PubMedDate not supplied

[Popliteal artery entrapment syndrome].

The popliteal artery entrapment syndrome is observed in about 0.5% of patients suffering from intermittent claudication, most often in young fit people. Significant diagnostic problems are the reason of frequent underestimation of the patients complaints. The development of the disease may further lead to lower leg arteries thrombosis or popliteal artery aneurysm. The latter condition is caused by abnormal course of the popliteal artery. Preliminary diagnostic procedures may comprise the examination with most simple Doppler apparatus. The diagnostic should be confirmed with the use of colour-Doppler ultrasonography or computed tomography (with contrast). The treatment of choice is an operation restoring normal anatomy within the popliteal space.

Adolescent↗