Biomedical subjects
Publications and source records attributed to K Zarrouk.
After anatomo-pathologic, épidemiologic and etiopathogenic description of canine Mast-cell tumor, the authors insist on the importance of this neoplasm in comparative pathology. Such animal model observation can be eventually used both in cancer Research and in allergo-dermatology.
The authors studied red cells from men and various animals for their capacity to mind to canine peripherical blood lymphocytes and form spontaneous rosettes.
After symptology's description of "Sticker sarcoma" the author gives a light on the origin of this néoplasm. He then indicates a new modality of treatment by electrontherapy in one time only, and proposes to give up histopathologic denomination "Reticulo Sarcoma" and replace it with "Sticker sarcoma" " Veneral non différentiated hematasarcoma" "Sticker sarcoma"
The authors describe the first Tunisian cases of hyperplasic Dermatosis of horses' limbs. They present both clinical and histopathologic aspects of this disease and try, consider etiopathogenic hypothesis.
The tumor Angiogenesis Factor (T.A.F.) isolated from several human and animal neoplasms by J. Folkman and S. Kumar is a factor that induces the appearance of neovessels in the tumors. After describing the methods of vasculor, physiological, experimental and in some cases pathological proliferation, the author has compared the Angiogenesis in both the natural and neoplastic tissues, then, he's studies the tumoral growth the rate of which regularized by the T.A.F. The proving, the extraction and chemical nature of this factor have been reviewed. Afterwards, the author has called to mind the notion of tumoral ecology and the various possibilities of inhibition of the tumoral growth, that is founded on the inhibition of the Angiogenesis and the therapeutical possibilities of the T.A.F. in the fight against cancer. To end up with his study, the author is now considering the possibility of using the T.A.F., extract of the sarcoma of sticker as a complement to the electontherapy in the treatment of this neoplasm.
Among the mononudear cells which participate in the different immunological mechanisms of cell destruction, the "K-cells" can induce in man, rat and mouse a cytotoxicity cell mediated depending on IgG type antibodies. Utilizing methods based on research works in man we were able to detect the presence of this K-cell in the peripheral blood of dogs.