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Biomedical subjects

K Zaghloul

Publications and source records attributed to K Zaghloul.

At least 37 records · Page 2Linked to original sources
PubMed2000

[The oculomotor effects of the fractures of the floor of the orbit].

PURPOSE: Fractures of the orbit floor have very disabling oculomotor after effects. The objective of this study was to report that close collaboration between the maxillo-facial specialist and ophthalmologist is necessary to avoid oculomotor after effects. METHODS AND PATIENTS: Our study included 10 cases of the fracture of the orbit floor. These cases were recorded between 1992 and 1996. RESULTS: This pathology affected young subjects aged between 20 and 40 years in 70 % of the cases. 80 % of the subjects were males. 90 % of the patients presented a vertical diplopia as a result of a transitory oculomotor deficit. 20 % of the subjects presented a permanent oculomotor deficit at the stage of after effects. All these deficits were of a mechanical origin and, contrary to other authors, we found no deficit with nervous sensory origin. CONCLUSION: Therapeutic success is based on early diagnosis and treatment that requires close collaboration between the maxillo-facial and ophthalmology teams.

Adult↗
PubMed2000

[Gyrate atrophy of the choroid and retina: a case report].

BACKGROUND: Gyrate atrophy of the retina and choroid is a rare disease, with recessive autosomal transmission, characterized by progressive chorioretinal atrophy causing blindness. It results from a congenital deficit in aminotransferase ornithine. CASE REPORT: The authors present the case of a young patient aged 15 years old consulting for a progressive fall of visual acuity with hemeralopia. Eye funduscopy showed regions of confluent rounded chorioretinal atrophy. The visual field, the electroretinogram and the retinal angiography were all alterated. Gyrate atrophy of the retina and choroid was evocated. DISCUSSION: It is a systemic and rare metabolic disease where ocular features are dominating. Differencial diagnosis are pigmentary retinopathies. Cataract and/or myopia are often joined to the retinal lesions. General signs could consist in muscular weakness, thin and rare hairs and mental retardation. More than; visual fields, electroretinogram, retinal angiography that are alterated; the plasmatic dosage of the ornithine is often high. The treatment is based on the dietetics with uncertain results. The genic therapy would be the treatment of future.

Adolescent↗
PubMed2000

[Juvenile xanthogranuloma with intraocular involvement. A case report].

Juvenile xanthogranuloma (JXG) is a rare and usually benign disease occurring in early childhood. It causes skin and deep seated lesions, notably in the eye. We report a case of JXG in the iris of a 9-month-old infant. Examination under general anesthesia revealed megalocornea, iris xanthogranuloma occupying the entire anterior chamber and high intraocular pressure. Skin lesions on the left lid and on the back were also found. Ocular hypertension resisted medical and surgical treatment. Cyclodestruction was necessary. The incidence of JXG is low (0.4%). The iris is the most frequently affected ocular tissue. Early diagnosis is necessary to avoid complications. Moreover, JXG can be associated in rare cases with neurofibromatosis or leukemia which must be systematically searched for.

Eye Diseases↗
PubMed1998

[Isolated and primary palpebro-conjunctival amylosis. Apropos of 2 cases].

Ocular amyloidosis a an uncommon condition and conjunctival involvement rarely occurs, representing 15% of all ocular localizations. Clinical manifestations show a polymorphism requiring a histological diagnosis. Based on two cases of primary isolated conjunctivo-palpebral amyloidosis, we discuss the different ocular sites. The first case involved false ptosis, a conjunctival infiltration and a lower eyelid tumefaction; all located in the left eye. The second case had ptosis, a right lower eyelid tumefaction with ectropion and esthetic damage. Amyloidosis was confirmed at histologic examination of the conjunctival mucous after a special congo red coloration. In order to affirm the isolated conjunctival localization, it is necessary to eliminate another amyloidis site. The treatment was surgical with excision and cure of ptosis. Ocular amyloidosis is a rare condition with polymorphism manifestations. Confirmation is histological. The greatest difficulty is management due to disease recurrence.

Adult↗
PubMed1997

[Bilateral Sturge-Weber-Krabbe syndrome. Apropos of a case].

We report a case of bilateral Sturge-Weber-Krabbe syndrome. The patient was a child aged 2 years. He presented facial and jugal angioma, bilateral glaucoma and epilepsy. The cerebral scan showed calcifications characterised by their localisations and their aspects. Cure and prognosis of this disease are discussed.

Child, Preschool↗
PubMed1997

[Malignant non-Hodgkin lymphoma in choroid and nasopharyngeal sites].

We report the case of a 55 year-old man admitted in May 1993 for squamous cell carcinoma of the nasopharynx (T2N2M0). Initial polychemotherapy and radiotherapy were performed in nasopharynx and cervical nodes. After 8 months of complete remission, a choroidian tumoral process appeared. Due to the rarety of this localization of nasopharynx carcinoma, we reviewed the diagnosis with immunohistochemistry that showed T-cell extensive immunoblastic non Hodgkin lymphoma.

Choroid Neoplasms↗
PubMed1997

[Ophthalmological involvement in Behçet disease. Apropos of 520 cases].

PURPOSE: The aim of this paper is to compare our results with the literature and to discuss some therapeutical aspects of the disease. METHODS: This retrospective study concerned 520 cases of Behçet's disease followed by internal diseases department and ophthalmology service of U.H.C. Averroes (Casablanca, Morocco) during 10 years. RESULTS: There were 432 men (83%) and 88 women (17%). The mean age of the patients was 20 years. Ophthalmological involvements are found in 80%, bilateral in 60%. The disease occurred at the rate of 2 or 3 episodes a year in 5% of cases. Irreversible blindness was noted in 24.4% of cases, predominately panuveitis in 37% of cases, followed by anterior uveitis in 36.3% and retinal vasculitis in 37% of cases. Good results were obtained by a medical care with corticoids and chloraminophen in case of threatening blindness. CONCLUSION: Behçet's disease remains frequent in our country. It requires early diagnosis and steady ophthalmological surveillance in order to delay onset of blindness.

Adolescent↗
PubMed1997

[Ophthalmological manifestations of Von Recklinghausen disease].

PURPOSE: To evaluate the frequency of Von Recklinghausen neurofibromatosis type 1 (NF1) ocular abnormalities. METHODS: A retrospective study was conducted in 11 patients during two years. RESULTS: We found Lisch nodules in 4 cases associated to conjunctival lesion in one case and to retinal hamartoma in another case. In two cases, we found an eyelid neurofibroma. One patient had orbital fibrosis dysplasia. Ocular disease revealed the NF1 in 4 cases, the tumoral exophtalmia in two cases. CONCLUSION: The ocular manifestations of Von Recklinghausen disease are frequent and can reveal the disease. Ophthalmologic examination must always be performed if Von Recklinghausen is suspected.

Eye Diseases↗
PubMed1996

[Anaphylactic shock caused by application of fluorescein on the ocular conjunctiva].

OBJECTIVE: Fluorescein is widely used in ophthalmology. Side effects related to fluorescein occur frequently but are usually benign (nausea, vomiting, lipothymia). Severe side effects are rare. We report a case of anaphylactic shock due to local application of fluorescein. CASE REPORT: A 70-year-old woman was treated for ocular conjunctivitis with local application of fluorescein. Cardiac arrest occurred due to anaphylactic shock. Resuscitation was successful. DISCUSSION: The gravity of certain complications related to the use of fluorescein underline the importance of adequate resuscitation material and adapted treatment.

Administration, Topical↗
PubMed1996

[Goldenhar syndrome: apropos of a case].

We report a case of Goldenhar syndrom in thirty eight old woman who has been refered to us for peribulbar choristoma. The authors discuss the different ophthalmological, otolaryngological and general manifestation of this syndrom and the therapeutic modalities of the ocular anomalies.

Adult↗
PubMed1992

Anthrax of the eyelids.

Anthrax is a disease caused by Bacillus anthracis. The disease affects primarily herbivores including sheep, cattle, horses, and other domestic animals. Humans may rarely be affected. We examined one male and two female patients with a localised itchy erythematous papule of the eyelid. A necrotising ulcer formed in each of the three cases resulting in a black lesion. Scraping in each case showed Gram positive rods and culture grew Bacillus anthracis. All three patients responded to the intravenous administration of penicillin G, and the lesion resolved leaving scars in two cases. Anthrax is a rare disease but should be considered in the differential diagnosis of ulcers or pustules of the eyelids.

Adult↗
PubMed1992

[Ophthalmologic manifestations in patients under chronic hemodialysis].

Ocular modifications were assessed in a prospective study carried out on 61 chronically hemodialyzed patients. Their mean age was 39.6 years (range: 7-73 yr) and the mean duration of dialysis was 30.5 months. The loss of visual acuity was especially associated with cataracts or refractive disorders. Corneal-conjunctival calcifications were found in 36% of the patients and were statistically significantly correlated with the duration of hemodialysis. Eyeground modifications were observed in 36% of the subjects; 21.3% of them were hypertensive retinopathies. Cataracts were less common (5%) than small calcifications in the lens (24.5%). Conjunctival biopsies taken from two patients confirmed the presence of calcium salt deposits under the conjunctival epithelium.

Adolescent↗
PubMed1989

[Mucocele of ophthalmologic expression and treatment apropos of 46 cases].

Mucoceles of the facial sinuses are benign tumors. They consist of a pouch made up from altered sinusal mucosa containing mucus ant inflammatory exudate. This tumors have a tendency to distension and to erode the bony walls. Their common site is in the anterior frontoethmoidal, rarely in the posterior ethmoidal or sphenoidal and exceptionally in the maxillary sinuses. They grow progressively at the expense of the eye and its annexes. Standard radiology is the main diagnostic key, but the scanner is essential to determine the extension and to evaluate the integrity of the posterior wall of the frontal sinus. Surgical intervention is the only way to treat a mucocele. The way of access to the mucocele can be either via the inferior way of Jacques or via the superior way of neurosurgical approach.

Diplopia↗