[The effect of controlled hypotension on central nervous system.--Part 1. The morphological study of cerebral microcirculation (author's transl)].
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Biomedical subjects
Publications and source records attributed to K Yada.
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A case of diffuse cerebrospinal gliomatosis is presented, with widespread involvement of the brain, cranial nerves, and spinal cord. This showed a far more extensive distribution of tumor cells than previously reported cases of gliomatosis cerebri. The clinical picture and oncogenesis of gliomatosis cerebri is briefly discussed.
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A case of malignant astrocytoma in the frontoparietal parasagittal region with transgression into the overlying dura mater and the skull is presented. Spontaneous transdural extension of a glioma is an extremely rare growth pattern. A mode of transdural extension of this tumor is discussed and related reports are reviewed.
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1. The antero-posterior diameter (APD-Fig. 1A) of the cervical spinal canals in 38 cases of symptomatic ossification of the posterior longitudinal ligament (OPLL) and 29 cases of asymptomatic OPLL was measured for each vertebra, and the thecoperiosteal diameter (TPD-Fig. 1B) of the cervical spinal canals in the same cases was measured. 2. The APD in the cases of symptomatic OPLL was found to be significantly smaller than those of asymptomatic OPLL. 3. The TPD in symptomatic OPLL was also found to be more significantly smaller than those of asymptomatic OPLL. Measurements of 9 mm or less were considered liable to be associated with cord compression. 4. The growing rate of the ossification was calculated in 13 cases of symptomatic OPLL which we have followed up radiologically for more than 2 years. The growing rate varied considerably from case to case. The average growing rate per one year was 4.07 mm in axial length and 0.67 mm in thickness on antero- posterior direction. 5. The incidence of OPLL was examined.
We have reported a rare case of spontaneous 3rd ventriculostomy with spontaneous arrest of obstructive hydrocephalus. A 41 year old man, who had had an intermittent headache for about a year, was admitted to the department of neurosurgery Kitasato University with chief complaints of sudden onset of severe headache, vomiting and disturbance of consciousness. At the time of admission, 30 minutes after the onset of symptoms, the positive neurological findings were delirious state of consciousness, miotic pupils with sluggish reaction to light, mild hemiparesis on the left site and slight nucnal rigidity. He lapsed into coma after two hours, however he gradually relieved from these symptoms since the forth hospital day. Cerebrospinal fluid was bloody. Radiograms of the skull revealed decalcification of posterior clinoid process and postero-inferior displacement of pineal calcification. Brain scanning and vertebral angiography demonstrated tumor stain in the posterior portion of the 3rd ventricle. Dimer-X ventriculography revealed the obstruction of posterior portion of the 3rd ventricle and the leakage of Dimer-X through the floor of the 3rd ventricle into the intrasellar subarchnoid space. The patient died after about one year from the onset of symptoms. Any signs of increased intracranial pressure had not been noticed since the forth hospital day; At autopsy we confirmed the posterior portion of the 3rd ventricle was obstructed by tumor. In the floor of the 3rd ventricle there was a round opening which was patient and measured about 3 mm in diameter. Microscopic examination of the tumor showed an oligodendroglioma. Neoplastic cells partially infiltrated into the surface facing to the 3rd ventricle and slight gliosis was observed around the site of rupture. The surface along the subarachnoid space was lined with pia-aracnoid membrane except at the site of rupture. In the past literatures only 6 cases of spontaneous 3rd ventriculostomy have been reported. Three cases were observed spontaneous arrest of obstructive hydrocephalus. Our case is the first reported case of spontaneous 3rd ventriculostomy through the floor of the 3rd ventriculostomy through the floor of the 3rd ventricle. We suggested the pathogenesis of spontaneous 3rd ventriculostomy is a result of destruction at normally weak points of 3rd ventricle (ex. anterior, posterior wall and floor of 3rd ventricle), which has the reultant internal hydrocephalus caused by recurrent obstruction of C.S.F. pathway or long-standing obstructive hydrocephalus.
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Following surgery for tumors in the hypophyseal or hypothalamic region, low serum Na level (hyponatremia) is sometimes noted and causes clinical manifestations. Therefore, on the care of patients within 1 to 2 weeks following operation for tumors in this region, stabilization of serum Na level is one of the most important problems.
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Osteochondroma is one of the most common benign bone tumors, but it is rare in the spine. A woman aged 54 was admitted for investigation of left nuchal pain with radiation to the occipital region for one and a half years duration. Physical and neurological examinations revealed no objective abnormalities. The cervical spine film showed the presence of a calcified mass in the left articulation between atlas and axis. Myelogram outlined a left sided filling defect at the level of a calcified mass. The tumor was totally removed using operating microscope technique through transcervical approach. This calcified mass was confirmed as the benign osteochondroma by histological examination. The patient became completely symptom-free after the operation.
Although many authors suggested vascular compression of venous system under increased intracranial pressure, the exact site and mechanism of the compression are still obscure. By the previous reports obtained in mongrel dogs, we clarified that a vascular stenosis took place 1-2 mm lateral to the junction between the lateral lacuna and the superior sagittal sinus as the intracranial pressure (ICP) was elevated. The present study was designed to reinvestigate the internal pressure of the intracranial venous pathways using crab-eating monkeys under gradually increasing ICP. (1) METHODS: Using crab-eating monkeys, pressure of the cortical veins and the superior sagittal sinus was measured by cannulating small calibred (0.4 - 0.5 mm in outer diameter) polyethylene tube. The ICP was elevated by inflating rubber balloon placed in the epidural space. Pressure of the above mentioned vessels, systemic blood pressure and ICP were measured with a standard pressure transducer. Pressure gradient between the lateral lacuna and the superior sagittal sinus was measured by moving to and fro the tip of small calibred tube which was inserted into the lacuna under operation microscope. (2) RESULTS: The pressure of the cortical vein was constantly 50 - 250 mmH2O (4-18 mmHg) higher than the ICP in monkeys, regardless of the level of ICP (Fig. 1, 2 & 3). Pressure of the superior sagittal sinus was quite stable at the low level untill the ICP was elevated up to 500mmH2O (36 mmHg) and more or less increased thereafter (Fig. 1 & 2). The pressure in the parasagittal venous pathways presented abrupt alterations between the lacuna and the superior sagittal sinus in monkeys (Fig. 6). (3) CONCLUSIONS: It was concluded that a gradual stenosis of parasagittal venous pathways took place 1-2 mm lateral to the junction between the lateral lacuna and the superior sagittal sinus in monkeys when the ICP was gradually elevated. This result suggests that also in humans a gradual stenosis occurs in a similar fasion as the ICP is elevated. The results of the experiment obtained in monkeys were almost the same as those previously obtained in dogs.
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The two approaches are well-known in the surgical treatment of atlanto-axial dislocation, the one is the anterior and the other is the posterior approach. The indication of these methods is still controversial. This report concerns with one case of atlanto-axial dislocation with the separate odontoid and bilateral obstruction of both vertebral arteries, which was successfully treated by transoral decompression and fusion between the bodies of the atlas and axis. The reasons why we chose this method were: (1) the spinal cord decompression was necessary because of the presence of compression of the cord by the separate odontoid process, (2) the spinal fusion had to be performed to stabilize the atlanto-axial articulation, (3) it was necessary to avoid the damage of collateral circulations to the brainstem through the deep cervical arteries demonstrated by bilat vertebral angiography. The posterior approach is highly susceptible to injure these collateral circulations.