The study is a result of many years investigations of a large pediatric team consisting of physicians from various specialities on the methods of management in cases of transposition of greater arterial vessels. Trials of surgical treatment requiring thoracotomy in the newborn with severe cardiorespiratory failure gave no good results. In recent years 65 operations of atrioseptostomy without thoracotomy were carried out during cardiac catheterization. In nearly half the cases improvement of the general condition was obtained with survival for several months or even over one year, but close supervision was required and the children were being prepared for more radical cardiosurgical operations.

Female↗

PubMedDate not supplied

Myasthenia gravis as a complication of D-penicillamine therapy in rheumatoid arthritis.

During the period 1971-79, 301 patients in the Voivodeship Integrated Hospital in Szczecin were treated with D-penicillamine (D-PCN). The complications observed included two cases of myasthenia gravis (MG), both in rheumatoid arthritis (RA) patients, one a 41-year-old man given the drug for 8 months, the other a 50-year-old woman treated in the same way for 4 months. In both patients, pneumomediastinography revealed enlargement of the thymus. Thymectomy followed by histological examination in both cases showed the existence of germinal centres and Hassall's bodies in the typical glandular texture. Follow-up examination 3 years later confirmed complete healing in the male patient and a marked improvement in the female patient.

Adult↗