The effects of acute exhaustive exercise, training and hypokinesia on cathepsin D activity were studied in the superficial ("white") layer of the vastus lateralis, in the deepest ("red") layer of the same muscle, in the soleus, in the heart muscle and in the liver of rats. In was found that acute exercise increased the enzyme activity in both portions of the quadriceps and in the liver. Training increased cathepsin D activity in the "red" quadriceps and in the soleus. In hypokinetic rats cathepsin D activity was markedly increased in each muscle investigated.

Animals↗

PubMedDate not supplied

Synthesis and activity of N alpha-(epsilon-aminocaproyl)-alanines and N epsilon-(epsilon-aminocaproyl)-caproic acid.

Four new dipeptides containing epsilon-aminocaproic acid were synthesized. Antibrinolytic, antiacaseinolytic activity and influence on activation of plasminogen by streptokinase were tested.

Aminocaproates↗

PubMedDate not supplied

Synthesis and activity of N epsilon-aminocaproyl-L-norleucine derivatives.

Five new derivatives of epsilon-aminocaproyl-L-norleucine were synthesized. Antifibrinolytic and anticaseinolytic activities were tested. All tested compounds were inhibitors of plasmin.

Aminocaproic Acid↗

PubMedDate not supplied

Effects of epsilon-aminocaproylaminoacids on fibrinolytic and caseinolytic activity of euglobulin fraction.

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Aminocaproic Acid↗