Single Point Imaging (SPI) is a 3D phase encoding MRI method proposed by S. Emid and J.H.N. Creyghton [1] to study solid state materials with a very short T(2) value (>50 micros). In this short communication experimental results of SPI applications to various industrial important solid materials, such as porosity of chocolate samples, connectivity of micro-channels in earth samples, etc. are reported.

Cacao↗

PubMedDate not supplied

The A1B genotype expressed as A2B on the red cells of individuals with strong B gene-specific transferases. Results from two paternity cases.

Two paternity cases involving black persons are reported in which possible paternal exclusions existed if the A2B red cell phenotype represented the genotype A2B. ABH transferase assays were performed to determine if the A2B phenotypes arose from the genotype A1B or A2B. These assays confirmed that all group A members carried the A1 gene and not the A2 gene. Therefore, the alleged father was not excluded in either case. The B transferase showed increased activity in both AB individuals, possibly accounting for the observed A2B red cell phenotypes. Therefore, in the presence of a B gene, accurate assignment of A subtypes using standard serological methods may not be possible.

ABO Blood-Group System↗

PubMedDate not supplied

[Recombinant tissue plasminogen activator in treatment of fulminant meningococcal infection].

This article reports about a young boy with fulminant meningococcal septicemia. Conventional treatment with antibiotics, intensive care and hemostatic drugs hold up vital functions. Because of extensive purpura fulminans with skin necrosis recombinant tissue plasminogen activator (rt-PA) was used. Under this therapy clinical improvement was observed.

Child, Preschool↗

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Speech and language therapy provision for bilingual children: aspects of the current service.

The findings are presented here of a questionnaire survey which asked speech and language therapy managers in England about the caseloads of the therapists in their trust as regards bilingual children. The survey was the first part of a larger research project aiming to explore why there appears to be over-representation of bilingual children in speech and language therapy in some areas and under-representation in others (compared to the proportion of bilingual children in the population). This main research question is discussed in relation to the literature and to the survey aims. The results describe aspects of the context in which the speech and language therapy service for bilingual children is operating: the lack of information about bilingual children is high-lighted. The staffing and training implications of bilingual clients' distribution over therapists' caseloads in areas with different levels of minority ethnic population are also considered. The finding that the majority of speech and language therapists in England who work with children (59%) see at least one bilingual child speaks of the extent to which issues relating to bilingualism affects therapists.

Child↗

PubMedDate not supplied

Educating nurses in political process: a growing need.

If we are to advance the profession of nursing, we must educate nurses to become key participants in the formulation of health policy. If we fail to do this, others will make decisions that affect our practice without our input. A growing number of nurses are recognizing the need to increase our power, and we understand that political participation provides a pathway to power. We must continue to increase the number of nurses who are politically astute and active in order to achieve our goal. The most effective way to accomplish this is to educate large numbers of staff nurses for this vital role. This article suggests educational strategies and methods that can be utilized in continuing education programs to begin the political education process.

Education, Nursing, Continuing↗

PubMedDate not supplied

Swallowing function and weight change observed in a phase I/II study of external-beam radiation, brachytherapy and concurrent chemotherapy in localized cancer of the esophagus (RTOG 9207).

BACKGROUND: A multi-institutional, prospective study was designed to determine the feasibility and tolerance of combined-modality chemotherapy, external-beam irradiation, and esophageal brachytherapy in a potentially curable group of patients with adenocarcinoma or squamous cell carcinoma of the esophagus. Swallowing function and weight were assessed before and after treatment. MATERIALS AND METHODS: Planned treatment was with 50 Gy of external-beam irradiation (25 fractions/5 weeks) followed 2 weeks later by esophageal brachytherapy (either a high dose rate of 5 Gy at weeks 8, 9, and 10 for a total of 15 Gy or a low dose rate of 20 Gy at week 8). Chemotherapy was given weeks 1, 5, 8, and 11 with cisplatinum, 75 mg/m2, and 5-fluorouracil, 1,000 mg/m2/24 hours in a 96-hour infusion. Swallowing was graded from 0 (no dysphagia) to 4 (complete obstruction for solids and liquids). Weight "loss" or weight gain was defined as a change in 3-month post- to pretherapy weight of < or = 5% or > 5%, respectively. RESULTS: The estimated survival rate at 1 and 2 years was 49% and 31%, respectively, and the estimated median survival was 11 months. Swallowing before treatment was graded as grade 1 in 14 patients, grade 2 in 22 patients, grade 3 in nine patients, and grade 4 in four patients. Swallowing grade after treatment was reported as improved in 29 patients (59%), unchanged in 12 patients (24.5%), and worse in eight patients (16.5%). The bestimproved dysphagia score after treatment in the 29 patients reporting improvement was grade 0 in 19 patients, grade 1 in five patients, grade 2 in four patients, and grade 3 in one patient. A posttreatment weight in 42 evaluable patients was categorized as a loss in 29 patients (69%), a gain in four patients (9.5%), and stable in nine patients (21.5%). Weight loss was significantly correlated with high swallowing grade, low performance status, and absence of a feeding tube. CONCLUSIONS: Swallowing function after brachytherapy and concurrent chemoradiation therapy is satisfactory in most surviving patients. Ninety-two percent of patients were able to swallow at least liquids at some point after therapy. Future plans are to compare this with other cooperative group studies that utilized chemoradiation or surgery, without brachytherapy.

Adenocarcinoma↗

PubMedDate not supplied

Hepatitis B virus mutants in HBsAg positive children.

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Child↗