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Biomedical subjects

K Williams

Publications and source records attributed to K Williams.

At least 505 records · Page 28Linked to original sources

Breast milk substitute: a bacteriological study.

The increased susceptibility of infants fed on cows' milk preparations has been attributed, at least in part, to differences in the nature of the large-bowel content-owing to the acidity of the faeces and their high content of Lactobacillus bifidus. In an attempt to mimic these features of the breastfed infant in one who is fed artificially, a breast milk substitute was devised which resembles breast milk in several important ways. When this material was fed to newborn infants the faeces developed the characteristics of those of the breast-fed child.

Acid-Base Equilibrium↗

An unusual hemoglobin anomaly and its relation to alpha-thalassemia and hemoglobin-H disease.

A Chinese family with hemoglobin H in the propositus has been reinvestigated. Although the original propositus is now deceased, a sister has the same hematological manifestations. Her hemoglobin, like that of the deceased sister, contains hemoglobins A, H, and Bart's. In addition, however, two minor components have been detected. These minor components appear to have abnormal alpha-chains and are also present in the maternal grandmother, the mother, a maternal aunt, and three other siblings but only in about one-tenth the amount. One of the minor components may be the same as Hb-Thai (25). The father has the characteristics of classical alpha-thalassemia. These results are discussed in relation to current concepts of alpha-thalassemia as they relate to "silent" and "classical" alpha-thalassemia and to possible multiple alpha-chain loci.

Adolescent↗