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Biomedical subjects

K Welch

Publications and source records attributed to K Welch.

At least 91 records · Page 5Linked to original sources

Computed tomography of Sturge-Weber syndrome in infants.

Computed tomographic findings in two infants with Sturge-Weber syndrome include calcification of the brain not visible on plain radiographs. In both cases, the choroid plexus was very prominent, and, in one, a hemangioma of the choroid plexus was found at surgery. In the other, especially dense deposits of mineral were identified at surgery to be calcified branches of the middle cerebral artery.

Angiomatosis↗

The intracranial pressure in infants.

In infancy, the intracranial pressure (ICP) is normally maintained at a level that is very low by standards that apply later in life. There is little or no overlap of normal pressure and the pressure in infantile hydrocephalus. Knowledge of the normal pressure may allow expectant management of milder instances of infantile hydrocephalus. During the first few days after birth, as the volume of the brain decreases so does its turgor, and subatmospheric ICP is common. Hydrocephalus may be masked or attenuated in severity during that time or may be incorrectly suspected in a normal child because of the increase in circumference of the head accompanying the restitution of volume. The postnatal decrease in ICP may be responsible for ventricular hemorrhage in the newborn.

Brain↗

Psychological changes following surgery for tumors in the temporal lobe.

Twenty patients with a tumor in the temporal lobe underwent extensive neuropsychological testing pre- and postoperatively, with special regard to verbal and nonverbal memory. All patients had bilateral abnormalities preoperatively. Contralateral functions tended to improve after surgery, contrary to the outcome expected in patients with bilateral abnormalities due to atrophic lesions. Computerized tomography was the most useful neurodiagnostic test in correctly identifying the nature of the lesion in these patients.

Adolescent↗

Residual shunt infection in a program aimed at its prevention.

Measures designed to prevent infection after cerebrospinal fluid shunts were described earlier. These include refinements in technique, postponement of operations when there is an actual or threatened leak of cerebrospinal fluid and the use of topical, systemic and intraventricular antibiotics. Six hundred and twenty-four operations in 404 patients, carried out after instituting these precautions were complicated by 13 new infections (2.1%) while in 5 instances (.8%) infection complicated a procedure conducted in the presence of a pre-existant but unrecognized infection. In almost every case the pathogenesis of new infection was clear. The circumstances suggest that some of the residual infections, both new and renewed, might by preventable.

Anti-Bacterial Agents↗

Syringomyelia following lumboureteral shunting for communicating hydrocephalus. Report of three cases.

Three patients are described in whom syringomyelia was identified long after the treatment of communicating hydrocephalus by a lumboureteral shunt. The reason for syrinx formation in these cases could not be determined. In two there was either autopsy-proven or presumed evidence for arachnoiditis, and in the third patient the symptoms of syringomyelia were acutely aggravated by temporary obstruction of shunt. The development of a pressure drop from the intracranial compartment to the spinal compartment with crowding at the foramen magnum is also a suggested mechanism.

Adolescent↗

Cerebrospinal fluid rhinorrhea via the fossa of Rosenmuller.

Traumatic cerebrospinal fluid fistulas in children are not rare as described by Harwood-Nash and Caldicott, North, and Simpson. Those involving the sphenoid bone apparently are rare, particularly in early childhood.

Cerebrospinal Fluid Rhinorrhea↗