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Biomedical subjects

K Wangerin

Publications and source records attributed to K Wangerin.

30 records · Page 2Linked to original sources
PubMed1977

[Embryology and etiology of the Poland and Amazone syndromes].

In 1841 A. POLAND described a rare complex of malformations in the male, characterized a unilateral pectoral muscle defect combined with ipsilateral symbrachydaktyly. If in the female a POLAND Syndrome is associated with ipsilateral hypo- or aplasia of the breast as a leading feature, we propose to name this entity "Amazone Syndrome". Altogether 5 POLAND Syndromes and 40 "Amazone Syndromes" were seen in our department. For the latter a morphological grading into four groups was performed for clinical purposes. The malformation complex of the poland syndrome develops between the 2nd and 5th week of gestation as a result of damage to an upper extremity bud. It is from this extremity-"Anlage" that the muscles of the shoulder girdle and the lateral thoracic wall (with common innervation by the brachial plexus) arise. In early embryonal life the lacteal ridge lies in close proximity to the exrremity bud. The "Amazone Syndrome" can be explained by simultaneous damage to an extremity bud and the lacteal ridge. Its aetiology is not clear. Lack of embryonal material, heredity, and teratogenic damage by medication are discussed. In our patients there was a strong suspicion of unwanted pregnancies with failed induced interruptions. On the other hand some siblings had various other congenital deformities. In conclusion we may state that any inhibition of the normal growth of the upper extremity bud may lead to the POLAND Syndrome, while a simultaneous damage to the extremity bud and the close-by lacteal mound may result in the "Amazone Syndrome.

Abnormalities, Multiple↗
PubMedDate not supplied

[Conclusiveness of various diagnostic procedures for squamous cell carcinomas of the visceral cranium and the oral cavity as compared with histological evaluations].

In 60 patients with primary squamous cell carcinomas of the oral cavity, clinical examination was complemented by 5 additional diagnostic procedures prior to surgery to assess tumor extension. Comparing these finding with the histological evaluation of the excised tissue demonstrated that, while the TNM classification remains the foundation of all tumor diagnostic procedures, the use of radiography, bone scintigraphy and CT is indispensable to ascertain the amount of tissue to be excised. CT competes with B-scan sonography in cervical lymph node diagnostics. Tumor scintigraphy has been found to be an unreliable method.

Aged↗
PubMedDate not supplied

[One-stage procedure for bimaxillary correction of extremely severe malocclusions. Pretreatment, planning and operation methods with functionally stable fixation of upper and lower jaws].

The comprehensive treatment of extremely severe malocclusion, carried out up to now in more than 30 patients, is described step by step. After the removal of the third molars, orthodontic treatment is provided to align the arches. This is followed by 4 weeks of bite plane treatment to bring back the TMJ condyles into their physiologic position, which is usually lost because of the undefined occlusal relationship. Following cephalometric analysis the surgical treatment plan is established on the basis of lateral cephalometric films aimed at orthognathic repositioning of the mandible and the maxilla. In addition, the one-stage bimaxillary correction is simulated in the articulator for the construction of occlusal splints. The intraoperative use of these splints and the fixation of the condyles at the zygomatic bone via positioning plates allows, for the first time, the reproducible physiologic adjustment of the condyle during the entire length of the operation. This method also permits three-dimensional control of the position of the repositioned maxilla. The functionally stable fixation of maxilla and mandible makes long-term postoperative immobilization unnecessary.

Bone Plates↗