Search PubMed⌕ Search

Biomedical subjects

K W Marck

Publications and source records attributed to K W Marck.

At least 37 records · Page 2Linked to original sources

Coupling the venous anastomosis: safe and simple.

Various anastomotic coupling systems have been developed aiming to facilitate microvascular anastomoses. Of these only the 3M Precise Microvascular Anastomotic System (MAS) has recently gained increasing popularity. However, clinical studies on the use of the MAS are sparse. We report our clinical experience with the MAS in a two-centre study between 1991 and 1996. Of the 96 MAS coupling rings used, 50 were accessible for final analysis, and a 100% patency rate was obtained. The main indication is venous end-to-end anastomosis in vessels of minimal discrepancy. In selected cases in head and neck surgery even end-to-side venous anastomoses appear to be feasible. Although it is not universally applicable for microvascular anastomoses, we conclude that, if appropriate, the MAS coupling device leads to a reliable venous anastomosis in a greatly reduced operating time of less than 4 minutes.

Adult↗

[Surgical removal of the lip vermilion in the treatment of lip carcinoma; experience in 8 patients].

OBJECTIVE: To present the results of lipshave surgery in patients treated for squamous cell carcinoma of the lip, with actinic changes. DESIGN: Descriptive. SETTING: Medical Centre, Leeuwarden, the Netherlands. METHOD: The histories were studied of 8 patients with carcinoma of the lip treated in 1988-1992 with lipshave surgery, if necessary in combination with a wedge excision. Postoperative results and lip function were observed; follow-up was from 9 to 53 months. RESULTS: Two patients died prematurely from another cause than the lip cancer. In the other patients there were no signs of recurrence of the carcinoma. Although all patients had decreased lip sensibility, lip functions were fairly intact: 2 patients complained of drooling at times or rarely, 1 drooled often and 3 never. For 1 patient speaking had become a little more difficult, in the other 5 cases it had not changed. The drinking test was performed properly in all cases. CONCLUSION: Lipshave surgery is a reliable treatment for lip carcinoma with actinic changes and also preserves the lip functions.

Aged↗

[Acral glomus tumors].

The glomus tumour is a rare condition occurring mainly in the fingers. The symptoms are characteristic: extreme tenderness together with cold intolerance, but the diagnosis is mostly delayed by many years, even decades. The relevant data of 20 patients with the tumour are presented. Extirpation of the tumour is the therapy of choice.

Adolescent↗

[Merkel cell carcinoma: a treacherous skin tumor].

Merkel cell carcinoma is a rare malignancy of the skin in predominantly elderly patients, frequently missed because of its inconspicuous aspect. The histological diagnosis is not always easily made. Four case histories are presented. Literature shows the aggressive biological behaviour of this tumour: the rate of local recurrence is 40%, of regional metastatic disease over 50%, while approximately half the patients with a Merkel cell carcinoma will die of this skin tumour.

Aged↗

A cryptic cause of monarthritis in the hand: the juxta-articular osteoid osteoma.

Three patients with an isolated arthritis in the hand are described. All three had long-term complaints and had undergone surgery before presenting in our clinic. The cause of arthritis, in all three patients, was a juxta-articular osteoid osteoma. In one patient the diagnosis was established by a plain X-ray. Additional radiological studies were necessary to arrive at the diagnosis in another patient, while in the third no preoperative diagnosis could be made, despite extensive investigations. Treatment consisted of curetting the nidus.

Adult↗

A tricky trigger finger: a patient with intermittent intrinsic locking of a metacarpophalangeal joint.

A trigger finger is not always caused by a stenosing tenosynovitis, but may rarely be due to an internal derangement of the metacarpophalangeal (MCP) joint. Several different mechanisms may be responsible for this intrinsic joint locking. A patient is described with intermittent locking of an index MCP joint due to an osteophyte tethering the radial accessory collateral ligament. Removal of the osteophyte solved the problem. Awareness of this condition may prevent unnecessary exploration of the proximal pulley and tendon sheath.

Arthritis, Rheumatoid↗

"New" microvascular clamps for thoracic surgery in the rat.

The development of "new" microvascular clamps for lung transplantation in the rat was necessary because the generally used microclamps were found to be not feasible in preliminary experiments. A mosquito clamp modified in a Satinsky-like manner made lung transplantation in the rat possible. However, most suitable was the smallest Blalock pulmonary clamp with some modifications. This clamp has been used in over 500 left lung transplantations in the rat now, and is no longer subject to further innovations. This report shows that relatively large instruments can be appropriate microvascular clamps.

Animals↗

Brachial artery rupture following supracondylar fracture of the humerus.

Rupture of the brachial artery following a supracondylar fracture of the humerus is rare. The case histories of two children with this injury are reported. Both were treated by open reduction of the fracture, fixation with two Kirschner wires and decompression of the forearm muscles. In one (who also had a rupture of the median nerve) the brachial artery ends were ligated and in the second they were anastomosed by interposition of a reversed vein graft. The postoperative course was uneventful in both cases. On re-examination, more than a year after the injury, the child with the ligated brachial artery had minor cold intolerance and a decreased systolic arterial forearm blood pressure. The indications for brachial artery repair are briefly discussed.

Brachial Artery↗

Lung transplantation in the rat: histopathology of left lung iso- and allografts.

The histopathology of pulmonary isografts and allografts in rats was investigated. During the first three days after transplantation the isografts showed scattered areas of exudate, containing polymorphonuclear leukocytes and macrophages, and a large number of type II alveolar cells with a highly pyroninophylic cytoplasm. One to two months later these pathological findings had completely disappeared. In contrast, the allografts were rapidly infiltrated with predominantly mononuclear leukocytes, from the second postoperative day onwards, eventually resulting in a more or less hemorrhagic and necrotic graft eight days after transplantation. Rat lung allografts are rejected faster than canine lungs, and more uniformly because of the use of inbred rat strains with defined histocompatibility mismatches. The rat model offers an advantageous model to study immunologic aspects of lung and heart-lung transplantation.

Animals↗

Lung transplantation in the rat. III. Functional studies in iso- and allografts.

Recently a microsurgical technique for orthotopic left lung transplantation in the rat was developed. The aim of this study was to investigate the influence of the operation itself and of an unmodified rejection reaction on the function of the transplanted rat lung. Orthotopic left lung transplantation was performed in 59 rats (34 isografts and 25 allografts). Isografts demonstrated a mean left lung perfusion of 23.1% in the first two postoperative weeks. Seven out of the 10 animals, subjected to a repeated scintigraphy 5-10 weeks later, had an increased graft perfusion, resulting in an almost normal mean left lung perfusion of 34.8%. At that time chest roentgenography revealed a good aeration of the grafts, that at autopsy had a normal aspect. Allografts showed an initial mean left lung perfusion (24.6%) similar to the isografts, which, however, declined sharply a few days later (4.3%). At that time chest roentgenography revealed totally opalescent grafts that at autopsy had the hepatized aspect characteristic of lung allograft rejection. These results of isogeneic and allogeneic lung transplantation in the rat were comparable with those of canine auto- and allotransplantation. For immunogenetic and economical reasons lung transplantation in the rat is a good alternative animal model in lung transplantation research.

Animals↗