Intracranial hemorrhage associated with overdose of decongestant containing phenylpropanolamine.
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to K W Kizer.
Explore the source record for details and available documents.
A spill of silicon tetrachloride (SiCl4) at a chemical plant caused the evacuation of several thousand people from an industrial park; 28 persons sought medical attention. Most of the affected individuals suffered only transient eye and upper airway irritation. Six of the plant employees were later referred for detailed evaluation of possible lung injury, but no definite evidence of SiCl4-induced pulmonary dysfunction was found. Five of these workers also experienced recurrent headaches, and two complained of pedal dysesthesias after the accident. Although the temporal relationship between the exposure and onset of these symptoms is notable, no definite etiologic relationship could be established.
Submersion injuries are a relatively common problem for emergency physicians. The primary physiologic problem in these patients is hypoxemia, and virtually all complications are secondary to this. Resuscitation depends of reversing hypoxemia and acidosis, then correcting the associated medical problems. Aggressive measures should be taken for all such patients, even after prolonged submersion, especially in young victims or when the water temperature was less than 70 degrees F. Despite prompt and vigorous resuscitation, though, residual neurologic deficits and deaths continue to occur after submersion injury. Clearly, prevention is the most important factor in reducing the morbidity and mortality from these injuries.
This discussion focuses on the several pressure-related syndromes that are peculiar to diving and that are collectively known as dysbarism. These include barotrauma of descent, barotrauma of ascent, and air embolism. Also considered are nitrogen narcosis and decompression sickness.
The author discusses the sources of exposure to toxic gases and fumes, particular toxic agents and their pathophysiology, and the management of toxic inhalation accidents.
Submersion accidents are an important public health problem in this country and worldwide, and they present a special challenge to emergency personnel. Submersion injury affects multiple systems but most notably involves the lungs, where ventilation-perfusion mismatching and intrapulmonary shunting result in hypoxemia, acidosis, and generalized anoxic injury. Resuscitation of the victims of submersion casualties should be directed at restoring respiration, improving oxygenation, correcting acidosis, and treating concomitant problems such as hypothermia, drug and alcohol intoxication, or cervical spinal trauma. With expeditious and proper treatment, most submersion victims have a good prognosis.
The health problems of diving are due primarily to the breathing of compressed air or other gas mixtures at higher than normal atmospheric pressure. This article focuses on the three main pressure-related syndromes that are collectively known as dysbarism. Emergency physicians should be familiar with the special considerations required in the management of victims of diving casualties.
Fifty cases of decompression sickness are reviewed in which recompression treatment was delayed for 12 hours or longer after the onset of dysbaric symptoms. Twenty-four patients (48%) had pain only. The other 26 patients (52%) had more serious decompression sickness; two patients may have had air embolisms. Ninety percent of the patients recovered either completely (66%) or substantially (24%) with recompression and associated treatment, although standard recompression protocols had to be lengthened in many of the cases.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Nontraumatic gas gangrene is extremely rare. It usually occurs following ulceration or perforation of an abdominal or pelvic viscus in persons having impaired host immune defenses. A fatal case of nontraumatic Clostridium septicum septicemia and myonecrosis in an elderly diabetic man with a perforated colon carcinoma is presented. The case illustrates the occult manner in which such cases typically present and the fulminant course of this disease. The need for rapid diagnosis and the current recommended treatment of gas gangrene are discussed.
Although high-dose corticosteroids have been widely recommended as an adjunctive measure in the treatment of serious decompression sickness, there are few objective data to support their efficacy in this disease. An unusual case of neurological decompression sickness which seemed to demonstrate a therapeutic response to steroids independent of recompression is presented. The various manifestations of decompression sickness and the effectiveness of delayed treatment are discussed.
The use of computed tomography (CT) in the diagnosis and management of decompression sickness and diving air embolism has not been previously reported. Two unusual cases of neurological dysbarism are presented in which CT was helpful in the postrecompression evaluation and treatment. CT showed areas of infarction and of edema of the brain. The role of CT in managing dysbaric diving accidents is discussed.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.