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Biomedical subjects

K Vest

Publications and source records attributed to K Vest.

2 recordsLinked to original sources

Automatic processes in word perception: an analysis from illusory conjunctions.

When asked to report the color of a target letter in a briefly presented word or pseudoword, Ss were more likely to report the color of letters from the same syllablelike unit than the color of other letters. Because Ss were not required to make a lexical decision or naming response, the multiletter units that are revealed by this task arise automatically. It was found that the syllablelike units are not phonological but correspond to orthographic patterns and morphemes. These units affect performance regardless of changes in letter-case, suggesting that the units are based on abstract letter identities. Unit formation was also not affected by visual field of presentation. Several experiments demonstrated that the morphological and orthographic units arise from different processes: The morphological units depend on lexical access, and the orthographic units do not. Finally, the effects of orthography are stronger for good readers than for poor readers.

Adolescent↗

Linkage analysis of schizophrenia: the D1 dopamine receptor gene and several flanking DNA markers.

Alterations in dopaminergic activity may play an important role in the pathogenesis of schizophrenia. The central effects of dopamine are mediated by at least five G protein-coupled receptors, D1, D2, D3, D4 and D5. The D1 receptor maps to 5q35.1 and it identifies an Eco RI as well as a Taq I RFLP. In the present study we undertook a linkage analysis between the D1 receptor RFLPs and schizophrenia in 9 multigenerational families in which segregation of disease was consistent with autosomal dominant inheritance and reduced penetrance. Several flanking DNA markers were also analyzed as the D1 receptor RFLPs were relatively uninformative in our families. Pairwise analyses of schizophrenia and several flanking markers indicate that inheritability of this region is unlikely to be involved in the pathogenesis of schizophrenia in the 9 families studied.

Chromosome Mapping↗