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K Venugopal

Publications and source records attributed to K Venugopal.

At least 19 recordsLinked to original sources
PubMed2005

New, simple and validated UV-spectrophotometric methods for the estimation of gatifloxacin in bulk and formulations.

New, simple and cost effective UV-spectrophotometric methods were developed for the estimation of gatifloxacin in bulk and pharmaceutical formulations. Gatifloxacin was estimated at 286 nm in 100 mM phosphate buffer (pH 7.4) and 292 nm in 100 mM hydrochloric acid (pH 1.2). Linearity range was found to be 1-18 mug ml(-1) (regression equation: absorbance=0.0684 x Concentration in microg ml(-1) + 0.0050; r2 = 0.9998) in the phosphate buffer (pH 7.4) and 1-14 microg ml(-1) (regression equation: absorbance = 0.0864 x Concentration in microg ml(-1) + 0.0027; r2 = 0.9999) in hydrochloric acid medium (pH 1.2). The apparent molar absorptivity was found to be 2.62 x 10(4) l mol(-1) cm(-1) in the phosphate buffer and 3.25 x 10(4) l mol(-1) cm(-1) in hydrochloric acid media. In both the proposed methods sandell's sensitivity was found to be about 0.01 microg cm(-2)/0.001A. These methods were tested and validated for various parameters according to ICH guidelines and USP. The quantitation limits were found to be 0.312 and 0.3 microg ml(-1) in the phosphate buffer and hydrochloric acid medium, respectively. The proposed methods were successfully applied for the determination of gatifloxacin in pharmaceutical formulations (tablets, injection and ophthalmic solution). The results demonstrated that the procedure is accurate, precise and reproducible (relative standard deviation <2%), while being simple, cheap and less time consuming and can be suitably applied for the estimation of gatifloxacin in different dosage forms and dissolution studies.

Anti-Bacterial Agents↗
PubMed2004

Epsilon wave.

Explore the source record for details and available documents.

Arrhythmogenic Right Ventricular Dysplasia↗
PubMed2003

Marek's disease, candidiasis and megabacteriosis in a flock of chickens (Gallus gallus domesticus) and Japanese quail (Coturnix japonica).

An outbreak of mortality in chickens and Japanese quail sharing the same airspace was investigated. Marek's disease was diagnosed in five of 11 chickens examined, and in 20 of 24 quail; crop candidiasis was found in four of the chickens and in five of the quail, and moderate to large numbers of organisms referred to as megabacteria were observed in eight of the chickens and 16 of the quail. The disease was so severe that almost all of the quail in the flock died or were culled during the following six months. In contrast, only approximately 5 per cent of the chickens died from Marek's disease.

Animal Feed↗
PubMed2003

A multi-purpose, self-adjustable aeroplane splint for the splinting of axillary burns.

External splinting has been acknowledged for many years as a useful approach for preventing and correcting burn contractures. Though this practice could be traced back many centuries, there is still a dearth of knowledge regarding a good splint to serve these purposes for axillary burns. The newly designed multi-purpose, self-adjustable aeroplane splint presented in this report helps in various ways, such as improving compliance, and positioning during preoperative, postoperative and rehabilitative phases of axillary burn management. It acts as a splint that provides circumferential pressure for scar management, provides prolonged stretch to contracted tissue and acts as a serial cast in increasing the shoulder range. Most of all, it is very much user-friendly, thus enhancing compliance and giving a good outcome in axillary burns.

Axilla↗
PubMed2003

The wrist in axillary burns--a forgotten focus of concern.

Need for splinting of the wrist in axillary burns is a question of great importance especially when there is no marked burns on the wrist and hand. This article presents various potential problems due to non-splinting of the wrist, various promising solutions for those problems and a better way of splinting a client with axillary burns. Modification in axillary splinting will definitely lead to a rewarding upshot in increasing the client compliance with no major complications not only in managing axillary burns but also in managing an array of disease conditions with shoulder limitations.

Axilla↗