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Biomedical subjects

K Ueyama

Publications and source records attributed to K Ueyama.

At least 55 records · Page 3Linked to original sources
PubMed1997

[Combined surgery for coronary artery disease and thoracic aortic disease].

Combined surgery in 6 cases who had coronary artery disease and thoracic aortic disease simultaneously was analyzed. Case # 1 had ascending aortic replacement under deep hypothermic circulatory arrest because of iatrogenic aortic dissection caused by aortic clamp during the routine coronary artery bypass grafting (CABG). Case # 2 had DeBakey type II chronic dissection. Case # 3 had type I aortic dissection 4 years after the initial CABG. Both case # 2 and # 3 had ascending aortic replacement under retrograde cerebral perfusion along with CABG. Transverse aortic replacement was performed in case # 4, # 5 and # 6 under selective cerebral perfusion along with CABG. Case # 4 was associated with ascending-transverse aortic aneurysm. Case # 5 had aortitis syndrome complicated with severe coronary ostial stenosis and cervical branch stenosis. Case # 6 also had aortitis syndrome, severe coronary ostial stenosis, heavily calcified ascending-transverse aorta, and mitral and aortic regurgitation. This case had mitral and aortic valve replacement additionally. Case # 2 died of low cardiac output syndrome and multi-organ failure postoperatively. Case # 4 did not recover from profound shock that followed the preoperative acute myocardial infarction. The problems of low cardiac output syndrome caused by long interval of ischemic cardiac arrest, and also the problems of proximal anastomotic site of saphenous vein grafts were discussed.

Aged↗
PubMed1997

[Postoperative evaluation of presealed vascular prostheses in surgical treatment of the thoracic aorta].

Two kinds of presealed vascular prostheses were started to use for the thoracic aortic surgery at May 1991. The Gelseal graft was implanted in 13 patients and the Hemashield graft in 31 patients. Each cases was performed enhanced computed tomographic scan periodically to determine the extent of postoperative dilatation of both grafts. These showed that the Gelseal graft is significant more dilated than the Hemashield graft (51.2 +/- 8.1% vs 10.2 +/- 5.8%: p < 0.001). The dilatation was almost completed within one month and no addition later on both grafts. Because of more dilatation and possibility of serous discharge, the Gelseal graft is not good prosthesis for the patients who require postoperative anticoagulant therapy. If the Gelseal graft is used, smaller size should be selected for its dilatation. As the result of this study, the Hemashield graft is more suitable for thoracic aortic lesions than the Gelseal graft.

Aged↗
PubMed1997

[Surgical correction of an incomplete endocardial cushion defect in a 66-year-old male with the remarkable pulmonary hypertension].

A surgical case of a 66-year-old male with an endocardial cushion defect (ECD) is reported. He had preoperative pulmonary hypertension (80/25 mmHg, Pp/Ps 0.61), hypoxia (63.7 mmHg) and decreased creatinin clearance (45.7 ml/min). Respiratory condition was New York Heart Association's (NYHA's) grade III. Angiocardiography showed a typical gooseneck deformity associated with mitral and tricuspid valve regurgitations with the cleft (Seller's grade II and III). As surgical correction, direct suture of the cleft in an anterior leaflet with mitral annuloplasty, patch closure of the ostium primum defect with Xenomedical patch and tricuspid annuloplasty were performed. Postoperative data were restored to NYHA grade I. decreased pulmonary artery pressure (43/21 mmHg) and resistances (Pp/Ps 0.36). The only three surgical treatments of an incomplete ECD were reviewed in over 65-year-old patients in Japan included one perioperative death. Although we suggest it should be actively taken surgical repair even in elderly patients with pulmonary hypertension.

Aged↗
PubMed1997

[Traumatic transection of the descending thoracic aorta with free open rupture in left pleural cavity--a case report].

A 33-year-old male was admitted to our hospital because of mediastinal bleeding by the traffic accident. He was in shock state. Chest roentgenogram showed widening of the upper mediastium, massive pleural effusion and deviation trachea to right. Chest CT scan showed left hemothorax and deviated mediastinum to right. Immediately after the end of the CT scan, the pulse of bilateral femoral artery was not palpable. Therefore, we started cardiac massage and carried to the operation room in a hurry. Under cardiac massage, median sternotomy was made. But, there were no abnormal findings in the ascending aorta and arch. Under ECC, left anterolateral incision was added. We found that the transection of the descending thoracic aorta was transversely without preservation of the adventitia and it reached a round of the aorta. Five cm of the descending aorta from just distal to the left subclavian artery was replaced with 22 mm Hemashield graft under the separate perfusion of upper and lower body and circulatory arrest. Postoperative course was stable and the patient was healthy at present.

Accidents, Traffic↗
PubMed1997

[Composite arterial conduits with internal thoracic artery and radial artery for a myocardial revascularization].

From April 1996 to December 1996, 15 patients were submitted to myocardial revascularization using composite arterial conduit with internal thoracic artery (ITA) and radial artery (RA). The age ranged from 51 to 76 years (mean age, 65.7 years); Forty patients were male. All patients had double or triple vessel disease or LMT disease. We used 28 arterial conduits including 15 left ITAs, 15 RA, 9 right gastroepiploic artery and one inferior epigastric artery. 15 RAs were anastomosed to LITAs and 15 composite arterial conduits were constructed (branched in 15). There was no operative deaths. Early postoperative angiographic controls demonstrated 93.3% (14/15) patency of composite grafts in 14 of 15 patients. The composite arterial graft using ITA and RA is feasible and the anastomoses so performed are completely safe.

Aged↗
PubMed1997

[Cardiac surgery in patients with chronic renal failure on maintenance dialysis].

From July 1988 through August 1996, 54 patients with chronic renal failure (CRF) on maintenance dialysis (50 hemodialysis = HD, and 4 continuous ambulatory peritoneal dialysis) have undergone some sort of surgical procedure requiring the use of extra corporeal circulation (ECC); 42 patients underwent isolated coronary artery bypass grafting (CABG), 8 valve replacement, 3 combined procedures and 1 correction of a congenital heart defect. The protocol called for maintenance dialysis on the day before surgery, large volume hemofiltration (HF) during the ECC period, postoperative K+ management with dextrose-insulin if required, and resumption of whatever preoperative maintenance dialysis 24 hours after the operative procedure. The mean diafiltrate volume of HF was 7963 +/- 2688 ml which was replaced with 6342 +/- 2748 ml. No patient required emergency HD before the resumption of the maintenance dialysis, although in 40% of the early patients HD was added on the second postoperative day. However as experience was gained, in the latter 60% of patients resumption of maintenance dialysis (HD 3 times a week) was thought to be sufficient. The incidence of calcification in patients with CRF is higher not only of involved coronary artery segments (4.5 +/- 2.3 segments; AHA coronary classification) than its counterpart without CRF, but also of the ascending aorta which mandated modifications of the technique in 6 patients (operation under ventricular fibrillation, cannulation access other than ascending aorta). The use of arterial in situ conduits for CABG was also thought to be advantageous, and the left internal thoracic artery combined to the gastro-epiploic artery was used in 11 patients (26.2%). Four patients died) (7.4%): 2 from arrhythmia, one from intestinal necrosis and one from multiple cerebral infarction. Thus we conclude that the outlined protocol is quite effective in controlling fluid and electrolyte balance in patients on maintenance dialysis allowing to undertake surgical procedures requiring the use of extra corporeal circulation relatively safely.

Adult↗
PubMed1997

[Pathological examination of radial artery--as a graft material for coronary artery bypass grafting].

To evaluate the usefulness of the radial artery (RA) as a graft material for coronary artery bypass grafting (CABG), the histologic studies of the RA were performed. Specimens were obtained from both sides of 10 RAs during the operations. The degree of arteriosclerosis was evaluated by two methods. The one was microscopic examination by a pathologist, while the other was used by NIH Image 1.57 system. Using this system, the pathological index of arteriosclerotic change was expressed as a ratio (Rx: internal luminal area/tunica media area) of the cross section. From the pathological view the tunica media of RA was rich in smooth muscle cells and poor in elastic fiber. And there was little arteriosclerosis in this artery. The mean Rx of the proximal side of RA was 0.177 +/- 0.033 and that of the distal side was 0.258 +/- 0.132. There was no significant difference between the two, but the proximal side of the RA was slightly larger than the distal. These results showed that RA has a low grade of arteriosclerosis. This was confirmed on microscopic examination. According to these results, the RA can be expected to be a suitable bypass material for CABG.

Aged↗
PubMed1996

Reduction in hippocampal formation volume is caused mainly by its shortening in chronic schizophrenia: assessment by MRI.

We performed contiguous, 1 mm thick, magnetic resonance imaging scans in 18 men with chronic schizophrenia and in 18 age-matched healthy subjects to test in living patients the findings of a previous postmortem study. The schizophrenic patients showed bilaterally shortening (left, -6%; right, -9%) and volume reduction (left, -9%; right, -11%) of the hippocampal formation (HF). Volumes of HF correlated positively with HF length in the schizophrenic patients. The reduction in bilateral HF volumes was small after controlling for HF lengths (left, -3%; right, -3%). In schizophrenic patients, significant negative correlations were found bilaterally between the length of HFs and the scores for attention, bizarre behavior, and positive formal thought disorder. The results suggest that the volume reduction seen in the HFs of schizophrenic patients was caused mainly by a shortening of the HF and that these clinical symptoms may be associated with shorter HF length.

Adolescent↗
PubMed1996

Phosphorus magnetic resonance spectroscopy in schizophrenia: correlation between membrane phospholipid metabolism in the temporal lobe and positive symptoms.

1. To determine any correlations between phosphorus metabolites in the temporal lobes and clinical symptoms in schizophrenic patients, the authors performed 31phosphorus magnetic resonance spectroscopy in 31 medicated patients and age- and sex- matched normal subjects. 2. Schizophrenic patients demonstrated an increased level of phosphodiesters (PDE) in the temporal lobes bilaterally and a decreased level of beta-adenosine triphosphate (beta-ATP) in the left temporal lobe. 3. A significant positive correlation was observed between the level of PDE in the left temporal lobe and the score of positive symptoms on the Brief Psychiatric Rating Scale. 4. These results suggest that altered membrane phospholipid metabolism in the left temporal lobe is associated with neuroleptic-resistant positive symptoms in schizophrenic patients.

Adenosine Triphosphate↗
PubMed1996

In situ right internal thoracic artery graft via transverse sinus for revascularization of posterolateral wall: early results in 116 cases.

The in situ right internal thoracic artery graft brought through the transverse sinus was used to revascularize the posterolateral wall in 116 patients. Its advantages were assessed retrospectively. The graft was anastomosed to the circumflex marginal branch in 70 patients (60%) or to the posterolateral branch in 41 patients (35%). One patient died (mortality rate 0.9%). Perioperative myocardial infarction occurred outside the territory of the right internal thoracic artery graft in 10 patients, four of whom required mechanical support for hemodynamic deterioration. Postoperative early angiography in 114 patients found the graft to be patent in 97.4%. The ratio of the diameter of the right internal thoracic artery to that of the recipient marginal branch was 0.94 +/- 0.18 (n = 69), and that to the posterolateral branch was 0.88 +/- 0.18 (n = 37) (not significantly different). Results of a postoperative stress test were abnormal in one patient (1/96 tested patients). This retrospective study suggests that the right internal thoracic artery brought through the transverse sinus to revascularize the posterolateral wall provided excellent early patency and good clinical results, even to the most distally located branches. This continues to be our procedure of choice for patients with multivessel coronary disease.

Adolescent↗
PubMed1996

The prognosis and the treatment of patients with a C3/4 spinal cord injury.

Twenty patients with a C3/4 spinal cord injury have been treated in our hospital since 1974. There were 15 new patients. The average follow up period was 68 months, ranging from 7 to 162 months. The 15 new cases were classified as Frankel A in nine cases, B in one, and C in five. Frankel A or B were usually accompanied by either an unstable spinal fracture or by spinal canal stenosis at the C3/4 level. Twelve patients received surgery. At the most recent follow up, eight of the 15 patients (53.3%) had improved according to Frankel's classification. Five, all Frankel A on remission, have died between 2 and 156 months after injury. Seven patients required tracheotomy on account of severe respiratory disturbance.

Adult↗
PubMed1996

Adrenal tumor producing 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone and aldosterone.

A case of adrenal tumor producing 11-deoxycorticosterone, 18-hydroxy-11-deoxycorticosterone and aldosterone is reported. A 55-year-old woman had hypertension, hypokalemia, low plasma renin activity and an adrenal tumor. The plasma level of aldosterone was normal, and the levels of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone were extremely high. After the tumor removal, the plasma level of aldosterone decreased and plasma levels of 11-deoxycorticosterone and 18-hydroxy-11-deoxycorticosterone were normalized. The tumor was benign adenoma and the production of steroid hormones was under control of adrenocorticotropic hormone. The enzyme activity of 21-hydroxylation in the tumor was elevated and that of 11 beta-hydroxylation was decreased compared with the adjacent tissue.

18-Hydroxydesoxycorticosterone↗
PubMed1996

[Coronary artery bypass surgery in patients over 80 years].

Coronary artery bypass grafting (CABG) was being performed with increased frequency in elderly patients. However, the results of operations in patients over the age of 80 years have not been previously reported in Japan. Between May 1988 and September 1994, we have performed CABG in 28 patients over the 80 years of age (group A: mean 82.2). These patients were compared with 240 patients in 60s (group B: mean 65.0). Mean New York Association functional class (NYHA) was significantly higher in group A (p < 0.01). Left main trunk stenosis was more frequent in group A patients (p < 0.01), while the number of diseased vessels did not differ. Preoperative use of an intra-aortic balloon pump (29%) and emergency operation (54%) were more frequent in group A patients (p < 0.01). There was no significant difference in the number of grafts per patient between the groups (2.93 for group A versus 2.93 for group B), but the internal mammary artery was used more frequently in group B patients (99% versus 39%, p < 0.01). In group A, the major complicatines were stroke, cardiac tamponade, reoperatin for bleeding and respiratory failure in 1 patient each (3.6%). The hospital mortality did not differ between the groups (0% for group A and 2.9% for group B). In group A, at mean follow-up of 16.3 months, 25 patients (89%) are alive and no patient had recurrent angina. We conclude that CABG in patients over 80 years of age can be performed with low mortality and significant symptomatic benefit. Patients should not be denied CABG because of age alone.

Age Factors↗
PubMed1996

[An evaluation of aortic root reconstruction using Carrel patch method with coronary anastomosis].

During the past 4 years, from January 1991 to December 1994, we experienced 12 cases of aortic root reconstruction utilizing Carrel patch method. The cases included annulo-aortic ectasia (AAE), root aneurysm with aortic regurgitation (AR), and aortic dissection with AR. The aortic valve and aortic root were resected, the coronary ostia were dissected free, mobilized, and then implanted to the composite graft. Coronary anastmosis was performed by mattress suture and reinforced by Tefron felt strips. It was necessary in one case to undergo coronary artery bypass grafting for myocardial ischemia due to coronary ostial stenosis. Operative procedure could be performed in 4 cases without blood transfusion. Post operative death was seen in only 1 case at 25 postoperative day, who underwent on emergency operation for cardiac tamponade due to aortic dissection. Pseudoaneurysm formations of coronary ostia or hospital death was not observed in any other cases during follow up period (average 25 months). Late tamponade was shown in one case as a complication, and the majority of cases had uneventful postoperative course. The operative procedure is considered feasible in any anatomic variation of the aortic root disease, even if dislocation of coronary ostia is minimal, and can be expect for prevention of pseudoaneurysm formation, and long term survival.

Adult↗
PubMed1996

[Cerebral complication during open heart surgery in relation to cerebral arterial stenosis documented by angiography].

To determine the cause of a cerebral lesion after open heart surgery, a cranial 4-vessel-study was performed prior to an elective operation in 89 patients, who were over 70 years of age and/or had a previous history of cerebro-vascular diseases (CVD). Patients with arterial stenosis over 75% to complete obstruction were categorized as the significant stenosis group and the others as the normal findings group. Of the 89 cases, 19 (21.1%) showed significant stenosis, among which six patients were found to have complete occlusion of the internal carotid artery. Seven patients (7.9%) developed postoperative neurological complications, with four patients having single or plural significant stenosis. Angiograms of three of those four patients revealed complete obstruction of their internal carotid arteries. The stenotic group showed a tendency toward neurological complications in comparison with the non-stenotic group although the incidence was not significant (p = 0.054). However analysis of the group with complete occlusion of the internal carotid artery indicated significant increased risk for cerebral complication (p < 0.013). Besides the 89 patients studied, an additional 479 patients who had not undergone preoperative angiography were subjected to this study whether the patient's age, previous history of CVD and extracorporeal circulation (ECC) time or aortic cross-clamp time were of the risk factors for postoperative cerebral complications or not. There was significant correlation between age (p = 0.044) and/or the previous history of CVD (p < 0.001) and neurological complications. Although there was no correlation between either the duration of ECC or aortic cross-clamp time and neurological problems within the whole study population, when only the patients over 70 years old and/or having history of CVD were studied, an increased tendency towards neurological complications was seen when the ECC time was longer than 120 minutes (p = 0.045).

Aged↗