Interaction of frusemide and digitalis on frog heart has been studied. It was found that like digitalis, frusemide did not have any effect on normal heart, but restored the normal myocardial contraction of the hypodynamic frog heart. Frusemide induced cardiac arrest when administered during digoxin infusion. It is suggested that interaction of frusemide and digoxin has additive effect.

Animals↗

PubMed1992

An analysis of hypotensive effect of synthetic oxytocin in rabbit.

Intravenous injection of synthetic oxytocin (Syntocinon) causes a fall of blood pressure in rabbit. The hypotensive response was potentiated after vagotomy and atropine. Beta-adrenergic and 5-HT blockers reduced the hypotensive response to oxytocin. Hypotensive response of oxytocin in rabbit involves two factors, activation of beta-adrenergic receptor and release of 5-HT.

Adrenergic beta-Antagonists↗

PubMed1977

Interaction between frusemide and tolbutamide on carbohydrate and uric acid metabolism.

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Animals↗

PubMed1970

A study of mode of pyretogenic effect of LSD25 in rabbits.

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Animals↗

PubMed1970

Antipermeability effects of some corticosteroids.

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Animals↗

PubMed1969

Hypoglycaemic effects of Bambusa dendrocalamus.

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Animals↗

PubMedDate not supplied

Modification of vascular response to synthetic oxytocin by oestrogen in rabbit.

Intravenously administered oxytocin caused a dose-related fall in blood pressure of the rabbit. When oxytocin was administered in oestrogen-primed animals, the depressor response was converted to a pressor one "Oxytocin reversal". The "oxytocin reversal." was abolished after treatment with dihydroergotamine, hexamethonium or adrenalectomy. The "oxytocin reversal" did not appear in reserpinized animals.

Adrenalectomy↗