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Biomedical subjects

K Todnem

Publications and source records attributed to K Todnem.

28 records · Page 2Linked to original sources
PubMed1989

Nerve conduction velocity in man during deep diving to 360 msw.

The function of the sensory and motor median nerves was examined in 6 divers during a simulated dive to 360 meters of seawater (msw), with a mixture of helium and oxygen (heliox) as breathing gas. Divers were examined in the compression chamber before the dive, at 360, 300, 240, 130, 50, and 5 msw, and with skin temperatures ranging from 29.2 degrees to 35.2 degrees C. Examinations were performed with superficial stimulating and recording electrodes. Fast sensory nerve conduction decreased with increase in hyperbaric pressure and with decrease in skin temperature. There was no significant correlation between slow sensory conduction and hyperbaric pressure. Distal motor latency increased with increase in hyperbaric pressure and with decrease in skin temperature. The effect of pressure was independent of temperature. No significant functional changes were detected in the main nerve trunk proximal to the wrist or in the F-wave responses.

Adult↗
PubMed1988

Seamen exposed to organic solvents. A cross-sectional study with special reference to the nervous system.

A cross-sectional study of 85 long-term solvent exposed seamen working on chemical tankers compared to 59 unexposed seamen. Symptoms from the nervous system, clinical neurological findings and neurographic measurements were studied. The examinations were performed at least 2 weeks after the last solvent exposure. A stepwise multiple regression analysis was used to evaluate the dose-response relationship between the registered data on one hand and solvent exposure, employment on chemical tankers, age, alcohol and chloroquine phosphate consumption on the other. A significant correlation was found between increasing solvent exposure and reduced sensory nerve conduction velocities, as well as between increasing solvent exposure and prolonged distal latencies of motor nerves, and between increasing exposure and reduction of action potential amplitudes of sensory nerves. No correlation was found between solvent exposure and symptoms from the nervous system or clinical neurological findings.

Chloroquine↗
PubMed1986

Transient visual disturbance during cardiac catheterization with angiography.

The occurrence of visual disturbances following cardiac catheterization with angiographies was studied in a prospective study of 2,006 consecutive adult patients. The overall incidence of visual disturbances was 1.0% and of complete blindness 0.2%. Women had higher incidence than men (2.0 versus 0.6%, p less than 0.01) and patients with a history of angina pectoris with normal coronary arteries had higher incidence than those with coronary artery stenosis (3.7 versus 0.8%, p less than 0.02). Thirteen of twenty patients also had signs of mental confusion. An abnormal electroencephalogram was found in 8 of 13 patients studied. Other neurological findings were observed in one patient only. All patients had complete recovery within 24 hours. Thus, the incidence of visual disturbances is found to be higher than earlier reported, but the visual loss is transient with a benign course.

Adolescent↗
PubMed1986

Cerebral ischemic attacks as a complication of heart disease: the value of echocardiography.

The association of heart disease and cerebral ischemic attacks, and the usefulness of echocardiography in detecting heart disease and possible embolic source, were studied in 194 patients with transitory cerebral ischemic attack or stroke. The study revealed 95 patients with heart disease, and 63 of them had positive echocardiographic findings. All together, 35 patients had heart disease as a probable source for systemic embolism. An undetected cardiac disorder, not found by clinical examination or electrocardiography, was detected in 25 patients. The cardiac disorder found by echocardiography only, was most frequently aortic and mitral valve disease. Thus, echocardiography is an useful tool in detecting heart disease in these patients.

Atrial Fibrillation↗
PubMed1979

A patient with Cronkhite-Canada syndrome, myxedema and muscle atrophy.

A case of Cronkhite-Canada syndrome is presented. The patient had alopecia, onychodystrophy and gastrointestinal polyposis, mainly in the stomach and duodenum, with transient diarrhea and hypoproteinemia. Marked atrophy and weakness of the shoulder girdle muscles due to myopathy were also present. In addition she had primary hypothyroidism. The outcome of the disease is usually fatal within months, but so far our patient is alive four years after the onset of symptoms. The pathological changes, pathophysiology, symptoms, course and treatment of this rare disorder of unknown etiology are discussed.

Aged↗