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Biomedical subjects

K Thompson

Publications and source records attributed to K Thompson.

At least 199 records · Page 11Linked to original sources
PubMed1983

Effects of stopping training on size and response to insulin of fat cells in female rats.

The parametrial adipocytes of exercise-trained female rats were smaller and had greater rates of 2-deoxyglucose uptake and glucose oxidation over a wide range of insulin concentrations than the fat cells of sedentary animals of the same age. The fat cells of the sedentary animals had a 180% greater volume than those of the trained rats, despite only a 9% difference in body weight. Following cessation of training adipocyte size increased rapidly; approximately two-thirds of the initial difference in fat cell volume between the trained and sedentary rats had disappeared after 9 days without exercise. Concomitant with the increase in fat cell size, the response of 2-deoxyglucose uptake and glucose oxidation to insulin diminished. There was a close correlation between fat cell size and the magnitude of the response to insulin of both glucose oxidation and 2-deoxyglucose uptake. It appears from these results that the effect of exercise training on the response of adipocytes to insulin is rapidly lost when exercise is stopped.

Adipose Tissue↗
PubMed1982

A more efficient biofeedback procedure for the treatment of nocturnal bruxism.

The study describes a noval approach in the use of a conditioning procedure for the treatment of nocturnal bruxism. The effectiveness of the procedure is demonstrated through its application with two nocturnal bruxists in controlled study designs. Subject 1 received several variations of this procedure and the result indicated that using a loud tone which she manually reset after awakening was the most effective approach to this treatment. The second study was designed to compare the effectiveness of relaxation training to the conditioning technique. Subject 2 failed to show any decrease in her bruxing behavior when taught relaxation. However, she showed immediate decreases in both frequency and duration of bruxing responses when treated with the biofeedback procedure. The need for future research in this area is discussed with emphasis on the development of low cost, home treatment units.

Adult↗
PubMed1981

Midshaft fractures of forearm bones in children.

Eighty midshaft fractures of the forearm bones in children are reviewed. These fractures occur predominantly in boys and are more frequent in the left forearm. The fractures can occur at any age, but the majority are seen between 6 and 8 years of age. They are divided into two groups: greenstick (Type 1) and displaced fractures (Type 2). Greenstick fractures (Type 1, 82.5 per cent) need only correction of the deformity without breaking the intact cortex, followed by supervized splintage for 6 weeks. Type 2(a) (3.8 per cent) fractures, where only one bone is displaced, were treated conservatively, but the displaced bone tends to heal with lateral angulation causing limited rotation unless adequately aligned surgically. Type 2(b) (13.7 per cent) fractures, where both bones are displaced, occur in young teenagers. The majority of these should be treated by internal fixation if adequate alignment cannot be achieved or maintained by conservative means.

Adolescent↗
PubMed1981

The prevalence of peptic ulcer in an institution for the mentally retarded.

Peptic ulcer was studied at a California institution for the mentally retarded. Of the 1,700 residents at risk, ninety-one were to have X-ray or endoscopy evidence of peptic ulcers, a prevalence rate of 5.4 percent. Ulcer prevalence in the duodenum was more than twice that in the stomach and oesophagus. All oesophageal, gastric, and duodenal erosions or ulcer craters, acute or chronic, were considered. The more severely retarded patients showed a higher ulcer prevalence than those less retarded, and males demonstrate higher rates than females. The presence of medical and neurological disabilities, including limitations of vision and communication, was positively associated with ulcer development. The results indicate a need for further study on aetiology of peptic ulcers in the retarded.

Adolescent↗
PubMed1981

Lack of Thy 1.2 antigen expression on the surfaces of mouse mammary epithelial cells.

Monoclonal antisera against mouse Thy 1.2 antigen were used to assess the expression of Thy 1.2 antigen on BALB/c and BALB/cfC3H normal mouse mammary gland epithelial cells (MMEC) and on spontaneous and transplanted BALB/cfC3H mammary adenocarcinoma cells. Immunofluorescence (IF) assays with the monoclonal anti-Thy 1.2 sera demonstrated that Thy 1.2 antigen was not expressed on the surface membranes of MMEC (both virus-free BALB/c and virus-infected BALB/cfC3H) and tumor (BALB/cfC3H) mammary epithelial cells. A specific antiserum against MMEC was used to establish the expression of this normal antigen(s) on the surfaces of both MMEC and tumor mammary epithelial cells obtained from virus-free and virus-infected mice. In addition, the expression of the mammary tumor virus envelope glycoprotein gp52 was determined by indirect IF on the surfaces of virus-infected mammary epithelial cells, both MMEC and tumor cells.

Adenocarcinoma↗
PubMed1980

Olfactory influences on the human menstrual cycle.

Two groups of women were compared for the timing of the onset of their menstrual cycles. One group was rubbed on the upper lip (directly beneath the nose) with a mixture of alcohol and underarm perspiration collected from a single female donor. The other group was rubbed with plain alcohol. The group which received the perspiration showed a significant shift in the timing of their menstrual cycles which conformed closely with the donor's monthly cycle. This is a preliminary study which supports the hypothesis that the time of menstrual onset may be modified by olfactory cues.

Adult↗
PubMed1979

Identification of mouse mammary adipose cells by membrane antigens.

Antisera produced to mammary adipose cells from midpregnant BALC/c females can be used to distinguish mammary adipose cells from mammary epithelial cells and fibroblasts. The mammary adipose membrane antigen detected by indirect immunofluorescence was found in adipose cells from (a) mammary glands of virgin, midpregnant and lactating mice; (b) mammary fat pads that had been surgically cleared of glandular elements; and (c) epididymis. In all tissues, this cell-surface antigen was removed by the enzymatic action used to dissociate the cells from the tissues and was shown to be fully restored when cells were cultured for 48 hr.

Adipose Tissue↗