[On the analysis of sodium suramine. 10. Report on the determination of pharmaceutic aids and drugs].
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Acridines↗
Biomedical subjects
K Thoma
Publications and source records attributed to K Thoma.
[Microbiological studies on the diffusion of antiseptics from ointment bases. 15. Report on the effect of pharmaceutic aids in the preparation of drug preparations].
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Acridines↗
[Adsorption anomalies in colloidal silicic acid towards invert soaps. 12. On the effect of auxiliary substances in the manufacturing of pharmaceutical preparations].
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Drug Compounding↗
[On the determination of the content of acridine derivates. 7. On the determination of pharmaceutical adjuvants and medicaments].
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Acridines↗
Environmental menstrual disorders.
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Adolescent↗
The high incidence of diabetes mellitus in the micronesian population of Nauru.
As a follow-up to surveys conducted three years ago among the Micronesian population of Nauru, the incidence and prevalence of diabetes mellitus was studied in 433 subjects aged 20 years and older. The diagnosis of diabetes was based on a 2-h plasma glucose of 200 mg/dl (11.1 mmol/l), enabling comparison with the Rochester, U.S.A., (Caucasian) and Pima (American Indian) studies. In both sexes the prevalence rate rose steadily with age, and the overall prevalence was 24% for both sexes. The overall incidence rate was 15.4 per 1,000 person-years. However, males had almost twice the incidence of the females (20.2% vs 11.5%). The incidence rate of diabetes in Nauruans was considerably higher than that found in Rochester and was second to that of the Pimas as the highest rate reported in the literature.
Adult↗
[Structure-dependent correlations of silicon compounds with drugs. 13. A report on the effect of auxiliary substances in the production of drug preparations].
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Adsorption↗
Comparative interphase cytogenetics using FISH on human ovarian carcinomas.
Analyses using fluorescence in situ hybridization (FISH) were performed on cytogenetic slides of 25 human ovarian carcinomas. Biotinylated alphoid DNA probes were used for the monocolor and bicolor detection of chromosomes #1, #7, #8, #11, #12, #17 and #20 in interphase nuclei of the target cell material. Specific loss of chromosomes #17 and #20 was the most significant finding in aberrant cell populations of the tumors, as was gain of chromosomes #7, #1, #8 and #11. By the use of probe combinations, the presence of combined gains and losses of several chromosomes within the same cell subpopulations could be shown in a series of tumors, while in others the significant numerical chromosome abnormalities found characterized various different cell populations. In summary, FISH could be shown to be a powerful tool of interphase cytogenetics, provided that its limitations are considered conscientiously.
Adult↗