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Biomedical subjects

K Terayama

Publications and source records attributed to K Terayama.

At least 73 records · Page 4Linked to original sources
PubMed1981

Effect of pyridoxal 5-phosphate on the activity of GOT isozyme in plasma from patients with Duchenne muscular dystrophy.

GOT isozyme (soluble GOT, s-GOT and mitochondrial GOT, m-GOT) activities with and without reactivation by the co-enzyme pyridoxal 5-phosphate (PALP) in plasma from 42 patients with Duchenne muscular dystrophy (DMD), and 11 normal controls were investigated. The magnitude of the enzyme activities in patients at the early stage of DMD greatly exceeded those of controls. As the disease progressed, the levels gradually declined, but late stage values were still higher than the control values except s-GOT with PALP. At the mid stage as well as the late stage, the increase in m-GOT activity was approximately to double the unstimulated activity, indicating that, in these patients, as much as half the m-GOT in the circulation was in the inactive apoenzyme form, whereas s-GOT showed negligible increase following PALP addition at any stage.

Adolescent↗
PubMed1980

Perthes' disease: a comparison between two methods of treatment, Thomas' splint and femoral osteotomy.

The results of twenty-four hips treated by femoral derotation varus osteotomy and sixty-six hips treated by Thomas' splint are compared. The average follow-up period was eight years with in a range of two to twenty years. All diagnoses were classified into Catterall's four groups according to the degree of epiphyseal alterations. Other factors affecting the outcome, such as subluxation of the femoral head, age at onset and stage at treatment were studied. Osteotomy improved the results remarkably in Group 3 and Group 4 hips. Femoral osteotomy would be indicated for those cases which show extended epiphyseal necrosis and subluxation of the femoral head. Even osteotomy has limitations in obtaining good results in older children with extended necrosis and in an advanced stage in which the femoral head is already deformed and regenerated.

Age Factors↗