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K Takakura

Publications and source records attributed to K Takakura.

At least 469 records · Page 26Linked to original sources

Percutaneous radiofrequency facial nerve coagulation in the management of facial spasm.

The authors have developed a fluoroscopy-assisted technique of percutaneous radiofrequency facial nerve coagulation at or near the stylomastoid foramen for management of facial spasm. The details of the procedure and the operative results in the initial series of 27 cases of facial spasm are described. The series included six men and 21 women, aged from 16 to 73 years. Twenty-four patients had classical, intractable, persistent hemifacial spasm, one had an unusual bilateral facial spasm, and one a postparalytic facial spasm. The age of onset varied from 16 years to 70 years. The duration of the symptoms ranged from 3 months to 11 years. Ten patients had undergone previous blunt-needle compression of the facial nerve from one to 10 times. The operative results in the 27 patients have so far been excellent. The longest follow-up has been 1 1/2 years. Although partial facial weakness was present in 60% of the cases, it invariably disappeared within 1 to 4 months. Only three patients experienced recurrence of spasm. In two of them, recurrence followed low-temperature coagulation. The procedure is simple, easy to perform, and extremely effective. It can be performed under local anesthesia in the outpatient clinic.

Adolescent↗

[Morphological and endocrinological study of ovarian arrhenoblastoma (author's transl)].

Morphological and endocrinological studies were performed on a 19-year-old case of an arrhenoblastoma with marked virilization. The tumor was an intermediate type of Meyer's classification. Histochemically, 3 beta-HSD and G-6-PDH activities were demonstrated in Leydig cells. These cells also had ultrastructures typical of steroid-producing cells. Basal blood cells of pregnenolone, dehydroepiandrosterone, testosterone (T), androstenedione (A), progesterone, estradiol, estrone, LH, and FSH were determined pre- and postoperatively. T and A showed a very high level preoperatively, and were markedly decreased immediately after removal of the tumor. Stimulation of tumor cells by HMG-HCG did not show any significant changes in their main products of T and A. These findings suggest that Leydig cells of the present tumor produced mainly A and T independently on gonadotropins, and these hormones had virilized the patient.

Adult↗

Red cell preservation and removal system of purine derivatives.

The new preservative containing high concentrations of adenine (8 mM), inosine (40 mM) and other chemicals which was indicated by Nakao et al., was applied to the preservation of red cell concentrates. Moreover, the system for the removal of purine derivatives (adenine, inosine and hypoxanthine) added and produced in stored samples was developed, using bead activated charcoal coated with the blood-compatible polymer (Hydron). Over 90% of purine derivatives in the medium and erythrocytes were removed by Hydron-coated bead activated charcoal (HAC) column. The recovery of erythrocytes by HAC column treatment was over 98%.

2,3-Diphosphoglycerate↗

[Therapy of glioma].

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Antineoplastic Agents↗

Thromboresistance of graft-type copolymers with hydrophilic-hydrophobic microphase-separated structure.

Graft-type copolymers composed of hydrophilic poly(hydroxyethyl methacrylate) (PHEMA) as a backbone and a small amount of hydrophobic poly(methylmethacrylate) (PMMA) as a long branch exhibit excellent thromboresistance. The interrelationship between the thromboresistance and microstructure of the graft-type copolymers as well as the water structure in the hydrated polymers has been investigated. It was concluded that both the structure of hydrophobic domain dispersed in the hydrophilic matrix and the water bound to the polymer may be responsible for the excellent thromboresistance of the graft-type copolymers.

Acrylic Resins↗