Search PubMed⌕ Search

Biomedical subjects

K Széll

Publications and source records attributed to K Széll.

At least 19 recordsLinked to original sources
PubMed2000

Does carbamazepine-epoxide conjugate with glutathione? On an existing but almost forgotten possibility.

The anticonvulsant carbamazepine is widely used to treat affective disorders and behavioural disorders in non-epileptic children. We report an elevated plasma level of carbamazepine-10,11-epoxide in a cystinuric child after daily medication with 300 mg carbamazepine while the serum level of carbamazepine was in the therapeutic range. The concentrations of carbamazepine and its epoxide derivative were determined by HPLC. The formation of a glutathione conjugate of carbamazepine-10,11-epoxide is raised as a hypothesis.

Anticonvulsants↗
PubMed1997

Thoracic and lumbar sympathectomy with the application of ROMICRO mini laparotomy set.

The authors present the use of ROMICRO set (originally developed for mini laparotomy) for thoracic and lumbar sympathectomy. They review 3 thoracic and 2 lumbar sympathectomy operations that had good effects and uneventful recoveries. The advantage of the method is that no special instruments are needed and it can be done as a conventional operation.

Cholecystectomy, Laparoscopic↗
PubMed1997

Cholecystectomy through a mini laparotomy alongside laparoscopic technique.

The authors present the surgical treatment of gallstones with special instruments and technique through a mini laparotomy, as developed in Kaposvár (Hungary). Despite the fact that the widespread use of laparoscopic cholecystectomy (LC) has succeeded over open cholecystectomy (OC), in their opinion, there are some instances where cholecystectomy through a mini laparotomy (MLC) would be advantageous. Last year (1996), in the authors' department, 32 MLCs were performed in addition to 72 OCs and 176 LCs. Due to unspecified techniques and differing criteria used to define MLC, it is difficult to find any data related to this subject in the literature available. In Hungary, there are two cities--Kaposvár and Szolnok--where only MLCs are performed for the surgical treatment of gallstones. Conversely, the University hospital of Szeged and the County hospital of Békéscsaba use all three procedures i.e. OC, LC and MLC; as is the case in the authors' hospital. In the article, the pros and cons of MLC are compared to those of LC. (The MLC being more cost effective, enables quick conversion to an OC if required, and provides the surgeon with a three dimensional picture, it is also suitable for the surgical treatment of common bile duct stones. However, it is cosmetically worse, obesity can cause technical difficulties, the incidence of hernia formation is higher, and wound healing is affected.) In the authors' opinion, it would be important to establish set criteria in order to screen patients that are unsuitable for LC, and they attempt to do so in this article.

Cholecystectomy↗
PubMed1994

[The lecture].

The author reviews the rules of conduct to be followed in lectures and he identifies a number of advices, useful for young colleagues. The fundamental ethical goal of lectures is to serve the audience as well as possible. The author touches upon the most important general rules of oral communications such as punctuality, discipline of remaining within time limitations, but he also describes advices how to work and deliver talks lectures. In conclusion he elaborates on his own view regarding the lecture opportunities that grow in our days, the effectiveness of which, however, leaves much to be desired.

Communication↗
PubMed1994

[Major theoretical and practical aspects of publications].

The author discusses some ideas concerning the sharing of scientific informations. The fundamental goal of the latter is to serve the readers as perfectly as possible. A physician of research ambitions may valuable contribute to the progress of applied sciences but this must not jeopardize the medical care of the patients. Reading relevant literature is one of the prime obligations of all doctors. The author raises some dilemmas and question concerning how to write publications while he attempts to clarify matters. He emphasizes that the importance of correctness of a publication is second to none. The problem of fragmentation and that of "double publication" is also briefly discussed. The author elaborates on how to identify the co-authors and the sequence they appear in the publication. He provides some hands- on advice as to the concise language and abbreviations. He enters the list for the qualitative improvement rather than quantitative increase of publications in Hungary.

Authorship↗
PubMed1994

Local anaesthesia and inguinal hernia repair: a cautionary tale.

Two patients undergoing inguinal herniorrhaphy developed transient quadriceps paresis after local inguinal nerve block. One sustained a compound fracture of the distal tibia and fibula. The importance of warning the patient and of increasing the awareness of nursing staff to the possibility of quadriceps weakness after use of local anaesthetic is emphasised.

Accidental Falls↗
PubMed1990

[Gallbladder torsion in infants].

The infrequent case of gallbladder torsion and accompanying Meckel's diverticulum in a 3-year-old girl, is described. Detorquation, cholecystectomy and resection of the diverticulum were performed. Condition of the development of the disease as well as its clinical aspects and therapy are discussed. It is suggested to explore the abdominal cavity for other developmental anomalies in the course of the operation. The patient recovered without complications and left the hospital 14 days after the operation.

Child, Preschool↗
PubMed1990

[Classification of polytraumatized patients, experience with the ISS system].

Authors assessed the process of healing of 161 polytraumatized patients from 1976- to 1987, treated intersively, using the ISS system. Mortality was 27 per cent. Independently from the ISS system the concomittant shock foretold invariably a bad prognosis, although this was also joined generally to a big point number. The ISS system is simple and characterized the degree of the injury well. Through it, it will be possible to measure the gravity of the injury, to estimate statistically the prognosis and to compare the different materials. The number of points in the ISS system shows a good correlation with the survival (death) and the length of the intensive treatment. No patient was lost below 28 points whereas over 49 only 2 have survived. The point value may give information only up to the level of statistical probability concerning the prognosis (or the activity of the treatment) of the single patients. Because of its simplicity, its wide spreading and good practical use the general introduction of the ISS point system, as basic system, is thought to be advisable. For a more accurate judging a further making better and completing of the system (age, conjoined diseases, factors influencing each other mutually) further of the use, if necessary, of the scores applied in accident surgery and intensive therapy seems to be suggested.

Critical Care↗
PubMed1989

Osmotic characteristics of sheep and cattle embryos.

Ten minutes of exposure to increasing concentrations of sucrose caused a proportional decrease in the volume of sheep late morulae, their relative volume changed as a linear function of the reciprocal of the osmolality of the medium. Day 6 sheep and Day 7 cattle embryos responded to the addition of permeating cryoprotectants by an initial shrinkage which was followed by gradual reexpansion. After 1.25 min exposure the relative volumes of sheep and cattle embryos respectively were 20 and 25% smaller in glycerol than in ethylene glycol. The volumes of cattle and sheep embryos remained smaller in glycerol than in ethylene glycol up to the final observation at 30 min. The osmotic response of sheep late morulae to 2.0 M propylene glycol was intermediate between their response to 2.0 M glycerol and to 2.0 M ethylene glycol. These results indicate that Day 6 sheep and Day 7 cattle embryos are more permeable to ethylene glycol than to glycerol.

Animals↗