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Biomedical subjects

K Szász

Publications and source records attributed to K Szász.

At least 19 recordsLinked to original sources
PubMed2001

[Decreased bone mineral density as a risk factor in the development of spinal deformities in neurofibromatosis].

Neurofibromatosis-1 is a here-do-familiar disorder that is associated with a variety of skeletal anomalies, mostly with spinal deformities in 10-50% of the patients. Intraoperatively, a poor vertebral bone quality has been observed. Efforts have been made to identify factors preventing curve progression, to optimize operational planning and to explain the pathomechanism. As part of the preoperative evaluation, the authors used a dual X-ray absorptiometry to assess the bone mineral density of the lumbar spine in 12 non operated patients with neurofibromatosis-1, supplemented by laboratory blood/urine investigations. A significant decrease in bone mineral density of lumbar spine was measured. An inverse relation was suggested between the severity of scoliosis and the lumbar spine Z-scores. No pivotal alterations were identified in the laboratory measurements. The bony tissue abnormality observed intraoperatively in neurofibromatosis-1 patients may be described as a diminution of the axial bone mineral density. The evaluation of bone mineral density in the course of the preoperative planning is proposed in neurofibromatosis-1.

Absorptiometry, Photon↗
PubMed2000

[Results of parathyroidectomy for primary hyperparathyroidism].

We have performed 16 operations on 14 patients with primary hyperparathyoidism caused by a solitary parathyroid adenoma in our department between 1st jan. 1990-31 dec. 1999. In each case bilateral neck exploration was carried out. As in one case it was located in ectopic neck position, in the other case papillocarcinoma of the thyroid gland and ectopic parathyroid adenoma in mediastinal position were present, primary hyperparathyroidism persisted, so reoperation was needed. Histological examination proved the presence of adenomin all cases. Diffuse hyperplasia and parathyroid cancer did not occur. Before operation all patients underwent US and seven of them had radionuclide scintigraphy. CT scan aided in its localization with four patients. We did not make use of invasive methods, after the first operation 12 patients showed normal S-Ca levels very quickly. In two cases this level was too high after the operation and reoperation was necessary which resulted in normal Ca levels. Even though the number of our cases is rather modest, all the patients recovered. This may prove that we can successfully cure our patients of modern methods of diagnostics used for meticulous examination alongside with careful preparation of the patients by internal specialists are followed by the standard operative techniques available.

Adenoma↗
PubMed1997

Epidemiology of congenital coronary artery anomalies: a coronary arteriography study on a central European population.

The anatomical patterns and frequency of occurrence of congenital coronary anomalies (CCA) in a Central European cohort has not yet been studied. The angiographic data of 7,694 consecutive patients undergoing coronary arteriography at the Albert Szent-Györgyi Medical University, Szeged, Hungary, from 1984 to 1994 were analyzed. CCA were found in 103 patients (1.34% incidence). Ninety-eight of them (95.2%) had anomalies of origin and distribution, and five (4.8%) had coronary artery fistulae. The incidence was the highest for the separate origin of left descending artery and left circumflex from the left sinus of Valsalva (52.42%). Anomalous origin of the left circumflex coronary artery from the right coronary was 8.7% while from the right sinus of Valsalva 18.4%. CCA, which may be associated with potentially serious events, such as ectopic coronary origin from the opposite aortic sinus (1.9%) and single coronary arteries (3.88%), were not frequent. The incidence of CCA in the Central European cohort under study was similar to that of the largest North American study. The anatomic classification presented can be useful from both clinical and surgical standpoints.

Adult↗
PubMed1993

[Value of the ejection fraction in patients with right ventricular necrosis during the rehabilitation period].

The right ventricular ejection fraction was determined in 58 patients with simultaneous right and left ventricular myocardial infarction and in 77 patients with only left ventricular myocardial infarction. The results were analysed in four groups of patients (patients with anterior, anterior and right ventricular, posterior, posterior and right ventricular myocardial infarction). Furthermore, the relation between left and right ventricular ejection fraction, stress capacity and heart volume was investigated. There was no influence of the age and gender of patients on the observed values of right and left ventricular ejection fraction. In younger patients, after myocardial infarction, the heart volume was found to be less and the stress capacity to be higher then in elderly patients. The right ventricular ejection fraction was normal in patients with "poor" left ventricular infarction, and it was decreased in patients with right ventricular myocardial infarction. The right ventricular ejection fraction did not influence the stress capacity and the heart volume of the patients. The left ventricular ejection fraction found to be less in anterior, compared to posterior myocardial infarction. This difference was independent on the presence of right ventricular infarction. The authors consider the decreased right ventricular ejection fraction as a valuable indicator of the abnormal contractility of the right ventricle even at the time of the rehabilitation after myocardial infarction.

Age Factors↗
PubMed1993

[Evaluation of hemodynamic parameters in patients with right ventricular infarction during rehabilitation].

Hemodynamic data in 43 patients with right and left ventricular infarction and 39 with left ventricular infarction were compared. Right atrial pressure, pulmonary capillary wedge pressure, mean pulmonary artery pressure, left ventricular end-diastolic pressure before and after ventricular angiogram, cardiac index, left ventricular stroke volume index, right ventricular stroke work index were evaluated, as well as ratios of right atrial and pulmonary capillary wedge pressure, right and left ventricular end-diastolic pressure, right ventricular end-diastolic and pulmonary capillary wedge pressure, left ventricular ejection fraction calculated from left ventricular angiogram, Berentey's score, and cardiac volume index. Using ONEWAY analysis there was no significant difference between the two groups in period of rehabilitation. In 15 patients with right ventricular infarction regression of ECG changes was observed in lead V3R also without significant influence on hemodynamic data.

Aged↗
PubMed1992

[False positive results of exercise tests with thallium myocardial scintigraphy].

The authors have examined supposed causes of positive Th-201 stress scintigraphy. Patients were divided into two groups according to the presence of exercise-induced transitory hypoperfusion or in absence of it. In both groups negative coronarograms were verified. Results of two groups were compared according to parameters of the left ventricle function, pulmonary pressure, to the presence of disorder of system stimulus-conduction (LBBB, RBBB), mitral prolapsus, foramen ovale apertum, anomalous coronary anatomy, level of load during exercise, body weight, heart volume-index. Significant difference was found in disorder of left ventricle motion, ejection fraction and in comprehensive value of left ventricle function (F1).

Adult↗
PubMed1992

Haemodynamic effect of nitroglycerin spray.

1. It is a reliable nitroglycerin (NTG) form influencing circulation and haemodynamics like other nitroglycerin products, 2. It is easily applicable, 3. Its use is advantageous especially for the prevention of pressure elevation occurring in response to physical exercise thus for the prevention of effort angina as well, 4. It is a reliable drug to be used in haemodynamic laboratories for measuring nitroglycerin effect, 5. Due to the rapidly developing fall of end diastolic pressure caused by the product it is also of value in controlling cardiac asthma attacks.

Administration, Inhalation↗
PubMed1991

[Angina pectoris, provocable by exercise, and silent myocardial ischemia in the light of results of coronary angiography].

Correlation between coronary anatomy and the presence or absence of chest pain was studied during bicycle exercise testing in 101 patients. All of them had significant ST segment depression during the stress test. ECG changes were accompanied by chest pain in 66 patients (group A). 35 patients were free of symptoms (group B). Coronary arteriography showed significant stenosis of one or more coronary artery branch in 50 patients of group A, and in 24 patients of group B, the difference was not significant statistically. The presence or absence of chest pain weren't valuable markers in the differential diagnosis of true and false positive ST segment depression. Frequency of three-vessel disease was significantly higher in group A (14 cases), than in the other group (1 case). In conclusion, if a significant ST segment depression occurs during exercise stress either with or without anginal pain coronary arteriography is recommended to perform.

Angina Pectoris↗
PubMed1991

[Normalization of the ECG in right heart infarct].

A 6-month ECG follow-up was carried out in 65 patients with right-ventricular infarction accompanied by anterior (n = 17) and inferior (n = 48) left-ventricular necrosis. QRS morphology and ST-segment alterations were evaluated in the period of rehabilitation and 6 months later. By the end of the 6th month, QRS in V3-4R returned to normal in 12 patients (18%), and there was no ST elevation in any of the patients at that time. Normalizations of QRS in V3-4R was about the same in the two groups and it was independent of patients' ages.

Adult↗
PubMed1990

[Normalization of ECG after right ventricular infarct].

6-month ECG follow-up was carried out in 65 patients with right ventricular infarction accompanied by anterior (n = 17) and inferior (n = 48) left ventricular necrosis. QRS morphology and ST segment alterations were evaluated in the period of rehabilitation and 6 months later. By the end of the 6th month QRS in V3-4R returned to normal in 12 patients (18%) and there was no ST elevation in none case by this time. Normalization of QRS in V3-4R was about the same in the two groups and it was independent from the age of patients.

Electrocardiography↗
PubMed1990

[Isolated right ventricular infarction].

Generally, right ventricle infarction is accompanied by left ventricle infarction. Isolated right ventricle necrosis is rare. Among 1707 patients with 6-week-old myocardial infarction there were 2 cases with isolated right ventricle infarction. Diagnosis based on pathologic Q waves in right precordial chest wall leads, radionuclide and echocardiographic observations. In one case, diagnosis was supported by coronary angiography, too.

Adult↗
PubMed1990

[Septal Q wave responses to exertion in the diagnosis of proximal stenosis of the anterior descending coronary artery].

In 29 patients with coronary artery disease (CAD) involving the proximal segment of left anterior descending coronary artery (LAD) and in 25 patients with normal coronary anatomy (control group) Q wave amplitude changes were studied in response to exercise with bicycle and treadmill. Decrease of the Q wave amplitude was observed only in the patient group. Increase in amplitude was found only in the control group. The sensitivity of bicycle test for a significant ST segment depression was 51.7%. The same value, obtained by treadmill exercise was 50%. When either a significant ST depression or decrease of Q wave amplitude was evaluated as an abnormal response to exercise, the sensitivity was 62% (bicycle) and 65% (treadmill). Taking both ST segment depression and reduction of Q wave amplitude, an increased sensitivity of exercise ECG examination can ben attained.

Coronary Disease↗
PubMed1990

[Stress tolerance in patients with right ventricular infarct during the rehabilitation period].

199 patients with myocardial infarction were divided into 4 groups according to the localisation of necrosis (anterior, inferior, anterior + right ventricle, inferior + right ventricle). Exercise capacity was determined by bicycle ergometer test at the beginning of rehabilitation and 3 weeks later. Exercise capacity and ejection fraction were better in case of inferior comparing with anterior infarction. There was no significant change in exercise capacity whether inferior or anterior left ventricle necrosis was accompanied by right ventricle infarction. In chronic phase of myocardial infarction exercise capacity of patients is not influenced by right ventricle necrosis accompanied by left ventricle infarction.

Exercise Test↗
PubMed1990

[The normal right-side electrocardiogram].

QRS complex, ST segment and T wave were investigated in V1R--V8R right chest wall leads in 122 healthy individuals (76 women, 46 men, mean age: 36.8 years). There was no Q wave in V1-3R. Going towards V8R, occurrence of QR and QS complexes increased. R/S ratio was the highest in V8R, while second r wave (r') was found to be most frequent (in 20.5%) in V6R. ST elevation at 80 msec after J point was found in all right chest wall leads, most frequently (in 91%) in V2R. All three forms of T wave morphology (positive, negative, isoelectric) were observed in these leads.

Adult↗
PubMed1990

[Experience with the Matti-Russe-Zolczer method in the surgical management of pseudoarthrosis of the navicular bone of the wrist].

Authors performed in the Department of Traumatology of the County Hospital Kaposvár from 1979 to 1985 22 Matti-Russe-Zolczer operations for pseudoarthrosis of the navicular bone. The necessity of the strict observance of the conditions of indication is stressed. The results of operations were assessed in a follow-up. The time elapsed between the operation and control was 2 and 6 years. Good results were achieved after the use of Matti-Russe-Zolczer operation in 22 patients with navicular pseudoarthrosis.

Accidents, Home↗