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Biomedical subjects

K Strojek

Publications and source records attributed to K Strojek.

45 records · Page 3Linked to original sources
PubMed1991

[Effect of occupational exposure in coke production on various parameters of the hematopoietic system].

The basic parameters of the erythrocytes, white blood cell and coagulation were determined in 201 workers exposed occupationally to organic substances containing benzene and its homologues. Occupational exposure to many factors during coke production, especially to high concentrations of BaP, did not cause perceptible changes in the erythrocytes. Moreover, total number of the lymphocytes was increased in the peripheral blood of exposed workers. That maybe considered as a nonspecific exposure test for the influence of the aromatic hydrocarbons. In haemostasis system the thrombocytopenia and the abnormalities of the plasma coagulation factors were revealed.

Adult↗
PubMed1990

[Effect of the work environment of the coke-processing industry on the respiratory system of coke factory workers].

The influence of the working environment in a coke factory on the respiratory system of workers was examined in 253 workers employed for at least 5 years at coke production in baking ovens, or at coke sorting and processing. They were exposed to high air concentrations of benzo(a)pyrene (BaP) and tar substances as well as other numerous toxic substances e.g. benzene++ derivatives, the level of which however, did not exceed the MAC values. Medical examination comprising the MRC questionnaire and spirometry , using Godart Expirograph, was carried out Among the exposed workers the non-specific chronic respiratory diseases with obstructive symptoms and chronic bronchitis were revealed more often than in the control group such factors as tobacco smoking and the duration of work also had their influence on the frequency of respiratory diseases. The possibility of the impact of high air concentrations of BaP and carbon monoxide cannot be excluded either.

Adult↗
PubMed1990

[Studies of immune system parameters in coke plant workers].

Studies on such parameters of immunological system as lymphocyte subpopulations percentage, immunoglobulins concentration and NBT reduction test were performed in peripheral blood obtained from 232 coke plant workers. All the subjects were divided into groups according to the degree of exposure to BaP. Lymphocyte T and B percentage, immunoglobulins IgG, IgM and IgA concentration and NBT reduction test in the examined groups were not significantly different from those in the control group. However, in subjects exposed to the highest concentrations of BaP the low percentages of lymphocytes T (OKT-3) and lymphocytes TH--helper (OKT-4) were revealed when the lymphocytes T subpopulations were examined (using monoclonal antibodies in indirect immunofluorescent technique). Presumably, the alterations the percentage of lymphocytes T subpopulations depend on high BaP concentration affecting the exposed workers.

Adult↗
PubMedDate not supplied

[Value of determining fructosamine levels in serum of pregnant patients with diabetes to evaluate the level of compensation for glycemia].

The results in 16 pregnant women with diabetes mellitus are analysed. All patients were treated with an intensive insulin-therapy at the Voivodeship Clinic for Diabetic Patients in Zabrze. Multipoint glycaemia profiles made by the treated patients as a self control were compared with serum fructosamine and HbAlC concentrations. A significant correlation of fructosamine levels with glycaemia and HbAlC levels was noted. No significant dependence of fructosamine and glycaemia fasting levels, incidence of hyperglycaemia and Schlichtkrull's Mw index was noted. Results suggest, that the fructosamine serum concentration is a useful marker of metabolic compensation in pregnant women with diabetes mellitus. It enables less frequent performance of the daily profiles of glycaemia by the patients.

Adult↗
PubMedDate not supplied

[A proposed model of the treatment of diabetes mellitus in pregnancy].

A model of management of pregnant diabetic patients is proposed. Such a model has been implemented at the Voivodeship Out-patient Clinic for Diabetics. Proposed model includes recent data on diabetes mellitus complications and the effect of coexisting diseases on the mother and fetus health. Management was adapted to the real and potential possibilities of health service in Poland. A decrease in the rate of mortality of fetuses under 7% was achieved. It is worth emphasizing despite higher value than those reported in the literature.

Blood Glucose Self-Monitoring↗
PubMedDate not supplied

Platelet aggregation in IgE-mediated allergy with elevated soluble Fc epsilon RII/CD23 level.

In 25 house dust mite-sensitive patients with perennial allergic rhinitis, an analysis of platelet aggregation tests (dual-channel aggregometer, Chronolog Corp, 345 model) induced by adenosine diphosphate (ADP) was carried out. The levels of total serum IgE specific antibodies against Dermatophagoides pteronyssinus and the soluble form of the low affinity IgE receptor (sFc epsilon RII/sCD23) were estimated as well. The study was carried out in a dynamic state, before and after 2 years of treatment with specific immunotherapy. We observed a significantly diminished platelet aggregation response, which partially improved after treatment. The results of this study suggest that platelet hyporesponsiveness might be involved in the pathogenesis of house dust mite hypersensitivity.

Adult↗