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Biomedical subjects

K Sperry

Publications and source records attributed to K Sperry.

34 records · Page 2Linked to original sources
PubMed1988

An epidemic of intravenous narcoticism deaths associated with the resurgence of black tar heroin.

In the latter part of 1985, a dramatic rise in the number of illicit narcotic (heroin) related deaths in the State of New Mexico became apparent, and this increase persisted through the majority of the following year. A careful inspection of samples of narcotics found at the scenes of death, coupled with changes in the illicit drug traffic detected by local and state law enforcement agencies, revealed that the rising death rate corresponded with the distinctively increased availability of a form of heroin that is produced in Mexico, commonly termed "black tar" heroin. An analysis of heroin deaths, comparing characteristics of cumulative deaths in the six years before the increase with those deaths associated with the apparent epidemic, revealed several significant observations. These factors, along with the distinctive physical features of black tar heroin, suggest that the rise in the narcotic abuse death rate may be related to both unfamiliarity with this type of heroin on the part of the user and the inherent difficulty of diluting nonpowdered forms of the drug to sublethal levels.

Adult↗
PubMed1988

An unusual, deep lingual hemorrhage as a consequence of ligature strangulation.

During the course of the daily practice of forensic pathology, little or no attention is generally devoted to the tongue (if it is even removed at all during the autopsy examination) except in a handful of relatively well-defined situations. In some other instances, such as injuries involving the neck and laryngopharyngeal organs, the tongue may be removed, but examined in only a cursory manner, since the serious pathology which caused or contributed to death is most often located in adjacent structures. While the postmortem examination was being carried out on a victim of ligature strangulation who exhibited relatively sparse external and laryngeal findings of significance, a unique and apparently heretofore undescribed patterned hemorrhage was discovered within the deep musculature of the tongue, having an appearance and contour identical to that of the curved edge of the subjacent hyoid bone. In difficult cases where strangulation is suspected as well as other potentially medicolegal problems with trauma involving the neck organs, a detailed inspection of the tongue through an easily accomplished dissection technique may provide invaluable information as to the mechanism of injury.

Aged↗
PubMed1988

Terminal ballistic characteristics of Hydra-Shok ammunition: a description of three cases.

The Hydra-Shok bullet is characterized by a hollow-point construction, with a distinctive central post in the base of the hollow. These features allow such missiles to be easily identified during the course of an autopsy examination of a gunshot victim. Higher velocity loadings of the Hydra-Shok may fragment along the wound path, occasionally forming a ring-like fragment that suggests this ammunition, but this feature cannot be considered unique. Although radiographic examination is helpful in bullet localization, the characteristic central post may be identified by X-ray only if sufficient expansion results in its exposure. Three cases of shooting deaths involving Hydra-Shok bullets are presented and discussed; in each case, the entrance wounds were indistinguishable from entrances associated with conventional ammunition, and in no instance did the missiles exit from the body (including head, chest, and abdominal wounds). Familiarity with relatively unusual ammunition types such as the Hydra-Shok allows for quick identification by the pathologist at the time of autopsy.

Abdominal Injuries↗
PubMed1987

Ultrastructural and immunofluorescent detection of herpes simplex virus after embalming and burial.

The practice of embalming preserves body tissues, and embalmed bodies may resist decay processes for many decades with relatively little change. As the chemicals used for embalming are poisonous to microorganisms, bacterial and viral cultures are futile after such funerary procedures are performed. However, embalming may act as a virtual tissue fixative, especially with arterial perfusion, and identification methods other than culture may be used to detect and identify pathogenic organisms. In the case presented here, a death from a fulminating, but unidentified, illness in a young girl was successfully diagnosed as herpes hepatitis by immunofluorescent and electron-microscopic studies of tissue obtained 3 weeks after she was embalmed and interred. Routine embalming and burial should not eliminate these diagnostic procedures from consideration in specific situations where potentially useful information may be realized.

Autopsy↗
PubMed1987

Fatal intoxication by tocainide.

A 26-year-old woman committed suicide by ingestion of a large quantity of tocainide, a recently developed oral antiarrhythmic agent with chemical similarities to lidocaine. Blood and bodily fluid analysis by thin-layer chromatography, high pressure liquid chromatography, and mass spectroscopy confirmed the presence of tocainide, with a serum level of 68 mg/L, nearly 7 times the upper recommended therapeutic level for this drug. Tocainide was also detected at significant levels in vitreous fluid and bile. Although the mechanism of death from tocainide intoxication in animal studies is related to central nervous system toxicity, the presentation of ventricular tachyarrhythmias with coma in this patient suggests that tocainide at high levels may have primary myocardiotoxicity in humans.

Adult↗
PubMed1987

Suicidal contact gunshot wounds to the head with .38 Special Glaser Safety Slug ammunition.

Glaser Safety Slug TM ammunition is a uniquely designed, essentially prefragmented ammunition. Tests performed by the U.S. Justice Department demonstrated that the ammunition possesses high kinetic energy, high relative incapacitation index (RII) and poses a very low risk to bystanders because of its total loss of kinetic energy in the target. Despite having been manufactured since 1974, no deaths from this ammunition have been previously reported. The authors herein describe the first three reported human deaths.

Adult↗
PubMed1987

Medicolegal aspects of necrotizing fasciitis of the neck.

Necrotizing fasciitis of the neck (NFN) is a relatively rare, fulminating infectious process of the cervicofacial tissues which may cause sudden and unexpected death. Although often the result of a dental infection, injuries of the soft tissues of the neck may also initiate rampant cellulitis, and recognition of the underlying etiology of such cases is necessary to determine properly the manner of death. Five cases of NFN are presented with a review of the causative factors and usual bacteriology, and specific factors of medicolegal interest are addressed.

Adolescent↗
PubMed1986

Sudden death due to a paraganglioma of the organs of Zuckerkandl.

A 20-year-old woman died suddenly in a hospital emergency room after presenting with nausea, vomiting, back pain, and hypertension. At autopsy, an extra-adrenal pheochromocytoma (paraganglioma) of the organs of Zuckerkandl was found, with microscopic focal myocardial necrosis similar to that described in death from adrenal pheochromocytomas. Tumors of the organs of Zuckerkandl are extremely rare; less than 100 such cases have been reported in the world's literature, and only six, including the present case, have presented as a sudden, unexpected death. The symptoms of catecholamine storm may mimic those of acute drug intoxications, leading to misdiagnosis by both clinical physicians and pathologists.

Adult↗
PubMed1980

Adenocarcinoma of the stomach with eruptive seborrheic keratoses: the sign of Leserp-Trélat.

The sign of Leser-Trélat, the sudden appearance of multiple seborrheic keratoses in conjunction with an internal malignancy, is very uncommon. A case involving a patient who had undergone resection of an adenocarcinoma of the sigmoid colon followed ten years later by the development of an adenocarcinoma of the stomach with exhibition of the sign of Leser-Trélat is presented. A summary of reported cases, along with a discussion of the sign, is provided. This is the first reported case of a patient presenting with the sign of Leser-Trélat along with a second primary malignancy.

Adenocarcinoma↗