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Biomedical subjects

K Slim

Publications and source records attributed to K Slim.

At least 37 records · Page 2Linked to original sources
PubMed2005

[Evidence-based analysis of prophylactic abdominal drainage].

Abdominal prophylactic drainage in digestive surgery was considered until recently as a dogma. But randomised controlled trials have questioned the routine use of abdominal drain in elective surgery. The aim of this review was to assess the usefulness of abdominal prophylactic drainage according to the concept of evidence-based medicine by analysing published randomised trials and meta-analyses. Levels of evidence vary greatly according to the type of surgery. One can conclude: with a good level of evidence that abdominal drainage has no place following elective cholecystectomy, appendicectomy and colectomy with intraperitoneal anastomosis; that it is perhaps unwarranted (lower level of evidence) following gastroduodenal surgery, pancreatectomy, splenectomy, and rectal surgery; and finally that could be indicated following oesophagectomy and common bile duct surgery (very low level of evidence). Nevertheless, when interpreting these data and evidence-based guidelines we should be consider the limitations of published studies (series coming from very expert teams, selected patients, short series, and elective surgery).

Abdomen↗
PubMed2005

[Pancreatic involvement in Wegener's granulomatosis: a rare and difficult diagnosis].

INTRODUCTION: Pancreatic involvement in the course of wegener's granulomatosis is rarely reported. EXEGESIS: We report a case presenting as a pancreatic tumorlike lesion. We also discuss six further cases from the medical literature. Two of them had a tumorlike lesion, three had acute pancreatitis and the last had exocrine pancreatic insufficiency. CONCLUSION: Treatment, association of corticoid and cyclophosphamide, is efficient if it is started quickly. So we think that this unusual manifestation of Wegener's granulomatosis should be recognized.

Aged↗
PubMed2005

[Evidence based surgery has some limitations].

Evidence based medicine can be defined as the application of the best evidence in the care of a given patient. When applied to surgical practice, it appears that this concept has some limitations. To discuss these limitations, the authors made the choice to discuss the terms the original definition. Some factors are related to the paucity and the poor quality of randomized controlled trials and meta-analyses in surgery, to the difficulties to appraise the surgical publications and apply the results of randomized trials to a given patient, and to bring the surgeons more willing to endorse the principles of evidence-based medicine. But all these limitations could be overcome making evidence-based surgery not to be a simple passing fad but a formal paradigm.

Evidence-Based Medicine↗
PubMed2005

French multicentre prospective observational study of laparoscopic versus open colectomy for sigmoid diverticular disease.

BACKGROUND: The aim of this study was to compare in-hospital morbidity and mortality rates after elective laparoscopic and open colorectal surgery for sigmoid diverticular disease (SDD). METHODS: This prospective national multicentre observational study included all consecutive patients undergoing open or laparoscopic elective colectomy for SDD in a 4-month period between June and September 2002. Postoperative in-hospital mortality and morbidity in the two groups were compared. RESULTS: Three hundred and thirty-two consecutive patients undergoing either laparoscopic (163 patients) or open (169 patients) colectomy for SDD were analysed. Overall postoperative mortality and morbidity rates were 0.3 and 23.8 per cent respectively. The morbidity rate was significantly higher in the open than in the laparoscopic group (P < 0.001), leading to a significantly longer hospital stay (P < 0.001). The morbidity rate remained significantly higher in the open group when the patients were matched for age (P = 0.015) or American Society of Anesthesiologists score (P = 0.028). An open procedure (relative risk (RR) 2.13 (95 per cent confidence interval (c.i.) 1.29 to 3.45)), age over 70 years (RR 1.62 (95 per cent c.i. 1.14 to 2.30)) and intraperitoneal contamination (RR 2.54 (95 per cent c.i. 1.18 to 5.50)) were identified as independent risk factors for morbidity. CONCLUSION: A laparoscopic approach to elective treatment of SDD may be associated with reduced postoperative morbidity and hospital stay. A randomized study is required to confirm these results.

Aged↗
PubMed2005

[Abecedary of the "Annales". Part 4].

The terms included and detailed in the present part are: case-control Study, Chi scare, Cochrane Collaboration, Cochrane Library, Cohort study, Coefficient of correlation, concordance testing, Informed consent.

Evidence-Based Medicine↗
PubMed2005

[Abecedary of the "Annales". Part 6].

The terms included and detailed in the present part are: cost-effectiveness analysis, cost-utility analysis, cost-benefit analysis, proportional hazards (Cox) model, inclusion criteria, endpoints or outcomes.

Cost-Benefit Analysis↗
PubMed2005

[Abecedary of the "Annales". Part 7].

The terms included and detailed in the present part are: dichotomous (variable), mean difference, normal (Gaussian) distribution, discrete(variable), discriminated (analysis).

Evidence-Based Medicine↗