Structure of a base in DNA modified by Glu-P-1.
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Animals↗
Biomedical subjects
K Shudo
Publications and source records attributed to K Shudo.
Identification of an ultimate mutagen of 10-azabenzo[a]pyrene: microsomal oxidation of 10-azabenzo[a]pyrene to 10-azabenzo[a]pyrene-4,5-oxide.
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Animals↗
Presence of 2-aminodipyrido[1,2-a:3',2'-d]imidazole in casein pyrolysate.
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Aminopyridines↗
Rat liver microsome-mediated binding to DNA of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a potent mutagen isolated from tryptophan pyrolysate.
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Animals↗
Mutagenicities of phenacetin and its metabolites.
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Genetic Techniques↗
Synthesis and mutagenicity of 10-azabenzo[a]pyrene-4,5-oxide and other pentacyclic aza-arene oxides.
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Aza Compounds↗
Reactions of K-region oxides of carcinogenic and noncarcinogenic aromatic hydrocarbons. Comparative studies on reactions with nucleophiles and acid-catalyzed reactions.
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Carcinogens↗
Ultramicro analysis of benzo[a]pyrene in food.
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Benzopyrenes↗
Isolation and structure studies of mutagenic principles in amino acid pyrolysates.
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Amino Acids↗
Enzymic formation of free radical from anthanthrene and 10-aza-benzo[alpha]pyrene lacking the bay region.
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Animals↗
Synthesis of a mutagenic principle isolated from tryptophan pyrolysate.
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Mutagens↗
Mutagenicity of K-region epoxides of polycyclic aromatic compounds: structure-activity relationship.
The mutagenicity of several K-region arene oxides was tested in histidine-dependent mutants of Salmonella typhimurium. Benzo(a)pyrene-4,5-oxide and pyrene-4,5-oxide as well as some substituted phenanthrene oxides were mutagenic in strains TA 1538 and TA 98 which detect frame-shift mutagens. Structure-activity relationships are discussed from the standpoint of chemical reactivity. The absence of direct correlation between electrophilic reactivity and mutagenicity may suggest that primilarily physical properties, such as relative position of the epoxide group and molecular shape of arene oxides, are important for the emergence of mutagenicity of arene oxides.
Benzopyrenes↗
Synthesis of (Pro-Hyp-Gly) n of defined molecular weights. Evidence for the stabilization of collagen triple helix by hydroxypyroline.
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Centrifugation, Density Gradient↗
Branched-chain glycosyl -amino acids. I. Stereospecific synthesis of 2-L-(3-deoxy-1,2-O-isopropylidene- -D-allofuranos-3-yl)glycine, an analog of the polyoxin sugar moiety.
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Antifungal Agents↗
New route to branched-chain sugars. Photoamidation and photohydroxyalkylation of 3-deoxy-1,2:5,6-di-O-isopropylidene- -D-erythro-hex-3-enofuranose.
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1-Propanol↗
Studies on protocollagen lysine hydroxylase. Hydroxylation of synthetic peptides and the stoichiometric decarboxylation of -ketoglutarate.
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Air Sacs↗
Synthesis of gibbane derivatives from enmein.
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Alkaloids↗
Conversion of enmein to (-)-kaurane. The absolute stereochemistry of enmein.
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Alkaloids↗