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PubMed1977

Heterogeneity and the modelling of bacterial spore death: the case of continuously decreasing death rate.

Models for the inactivation of bacterial spores for the case of continuously decreasing death rate are reviewed and extended to show that it is not possible to distinguish between one particular model based upon the innate heterogeneity of the population and that based upon the acquisition of heat resistance during the heating process. Two innate heterogeneity models have been fitted to published data.

Adaptation, Physiological↗

PubMedDate not supplied

Chronic compartment syndrome: diagnosis, management, and outcomes.

A consecutive operative series of 100 patients with chronic compartment syndrome involving 233 compartments is reported. Seven of every eight were athletes, and runners predominated. Exercise-induced symptoms of consistently recurring tightness, aching (in some, sharp pains) in anatomically defined compartments were pathognomonic. Mean months of symptoms prior to operation was 22; median age was 26 years. Bilaterality occurred in 82. The distribution of compartments was: anterior, 39%; lateral, 12%; and posterior, 48%. Incidental compartment pressures were elevated (mean = 23 mmHg). Fasciotomy using local anesthesia was performed on 70 outpatients. At a median of 4.5 months, over 90% were cured or significantly improved in symptoms and/or function. Median time to walking unassisted was 2 days, and to resumption of conditioned running 21 days. Fasciotomy can be a safe, effective, and economical treatment for chronic compartment syndrome.

Adult↗