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Biomedical subjects

K Semm

Publications and source records attributed to K Semm.

At least 91 records · Page 5Linked to original sources
PubMed1988

[Possibilities and limits of contact hysteroscopic assessment of the causes of postmenopausal bleeding ].

In this study, the contact-hysteroscopic findings are compared with the histopathological diagnosis of 168 patients who were treated for post-menopausal bleedings. The good diagnostic agreement between contact-hysteroscopy and histopathology in mostly benign alterations like atrophic endometrium (94.7%), polyposis (87.5%), mucosal polyps (88%) and myomas (100%) is not achieved in precancerous (77%) and cancerous (75%) lesions. Being an optical method, contact hysteroscopy necessarily fails in the evaluation of origin, dignity and degree of differentiation of malign lesions, and is no substitute for a histopathological diagnosis. Therefore, contact hysteroscopy may only provide additional information to dilatation and curettage and thus optimize results and diagnostic security.

Adenocarcinoma↗
PubMed1987

[Diagnosis and conservative treatment of tubal pregnancy using pelviscopy in comparison with laparotomy].

Operative pelviscopy substitutes at the Department of Obstetrics and Gynecology, University of Kiel, laparotomy for the treatment of tubal pregnancy in ruptured and non-ruptured tubes. Tubectomy, as well as tubal incision with the extraction of the pregnancy product and consecutive suture of the tubes is possible by pelviscopy. All patients with conservative treated tubal pregnancy by pelviscopy are explained that remnants can remain; careful beta-hCG-measurements over a time of at least 14 days post operatively have to be performed. Pregnancy rates in patients with the desire to have children after the pelviscopic treatment reach the same level of success as after a treatment by laparotomy. The operation technique is for the patient less physically stress-full and leads to a faster healing process. The hospitalization time with this treatment is shortened to a maximum of 2-3 days.

Chorionic Gonadotropin↗
PubMed1987

[Development of clinical pictures of ovarian deficiency following hysterectomy and destructive fallopian tube sterilization procedures].

30 patients who had been hysterectomized at the Kiel University Clinic of Obstetrics and Gynecology, and 83 patients who had undergone tubal sterilization by monopolar high frequency current or by endocoagulation according to Semm, were investigated with respect to endocrinology and to vaginal cytology. Plasma levels of 17-beta-estradiol, progesterone, FSH and LH were determined at short intervals for 2-3 menstrual cycles. Biphasic cycles and a relatively good estrogen response of the vaginal smears were found in the majority. In contrast, estrogen levels were slightly diminished when compared to controls of the same age group, and progesterone levels were markedly reduced, in particular in the middle luteal phase, with a corresponding gonadotrophin increase. These observations were made in women after hysterectomy, and after sterilization by monopolar high frequency current, in particular those who developed climacteric symptoms 2-3 years later. Comparable hormonal changes were not found in patients free of symptoms after "radical" endocoagulation or in any of the patients after the tissue-saving "modified" endocoagulation technique.

Adult↗
PubMed1986

German pelviscopic statistics for the years 1978-1982.

The second set of statistics on pelviscopy in Germany included information on 269,603 pelviscopies done in 322 general hospitals, and 22,859 pelviscopies done in private clinics between 1978 and 1982. In general hospitals the rate of serious complications was 1.9% and in private clinics 2.0%. Injuries to large blood vessels headed the list of complications. The main technique for tubal sterilization was the bipolar high-frequency current method with 75% in general hospitals and 73.1% in private clinics, followed by the endocoagulation technique according to Semm (36.8%). Sterilization failures were reported in 2.6%. Most failures were reported after sterilization with the bipolar electrocoagulation technique, followed by the clip technique. The rate of post-sterilization ectopic pregnancies was 1.06%. The highest rate of ectopic pregnancies was reported after using the bipolar tubal sterilization method (1.4%).

Blood Vessels↗
PubMed1986

[Pelvi-trainer, a training device in operative pelviscopy for teaching endoscopic ligation and suture technics].

Unlike in laparotomy, the art of pelviscopic surgery cannot be learned through assisting. For this reason, a training dummy, called a Pelvi-Trainer, has been developed. With this device, all surgical measures occurring in abdominal surgery can be simulated, such as adhesiolysis, internal ligature, internal sutures, resection, adnexectomy, enucleation of myomas, etc. The Pelvi-Trainer, designed for a three-stage plan, allows one to become gradually acquainted with the field of endoscopic surgery, and to make the transition from binocular vision to perfect three-dimensional control over intra-abdominal surgery under monocular endoscopic vision.

Endoscopes↗
PubMed1986

[Not Available].

Explore the source record for details and available documents.

Germany↗
PubMed1986

Ovarian failure phenomena after hysterectomy.

Previous studies have shown that simple hysterectomy with both ovaries left intact may cause ovarian failure. Questionnaires on climacteric symptoms were mailed to 243 patients between 27 and 42 years old who had been hysterectomized during the past ten years in the Kiel University obstetrics and gynecology clinic. From the 164 replies we found typical signs of ovarian failure in 39%. Some of the patients were asked to undergo endocrinologic investigation, which showed biphasic cycles in most cases. However, the average progesterone and estrogen concentrations in the suspected luteal phases were lower than in healthy women in the same age group.

Adult↗
PubMed1985

[German pelviscopy statistics 1978 to 1982].

The second statistics concerning pelviscopy in Germany included information about 269603 pelviscopies done in 322 general hospitals and 22859 pelviscopies done in 62 private clinics between 1978 and 1982. The participation of 38.7% for general hospitals and of 43.3% for private clinics may be explained by the fact that a major part of the participating clinics keep no detailed documentation on their operative procedures or cannot answer extensive questionnaires for lack of personnel. In general hospitals the rate of serious complications was 1.9% and in private clinics 2.0%. Injuries of large blood vessels topped the list of the complications (36.3% or 43.2%) (Bisler et al. 1980, Erkrath et al. 1979, Cognat et al. 1976, Mintz 1977). The rate of serious complications occurring in general hospitals and private clinics could certainly be lowered by intensifying the training in pelviscopic operation techniques (e.g. with the training phantom according to Semm) and by avoiding risky procedures like high frequency coagulation techniques in endoscopic operations. The predominant technique employed in tubal sterilisation was the bipolar high-frequency current method with 75% in general hospitals and 73.1% in private clinics, followed by the endocoagulation technique, according to Semm (36.8%). Sterilisation failures were reported in 2.6% or 2.5%. Most failures were reported after sterilisation by the bipolar high-frequency technique (3.9%) followed by clip technique (3.7%), and only very rarely in endocoagulation (1.1%). The rate of ectopic pregnancies following sterilisation was 1.06% = 40.6% of the total pregnancy rate after fallopian tube sterilisation or 0.68%.(ABSTRACT TRUNCATED AT 250 WORDS)

Endoscopy↗
PubMed1985

Use of a modified test system to determine early pregnancy factor (EPF) levels in patients with normal first trimester pregnancy and after therapeutic abortion.

Human pregnancy can be recognized as early as 48 hours after conception using the rosette inhibition test (RIT) to detect early pregnancy factor (EPF). A modification of the test as originally described by Morton et al. is demonstrated using a monoclonal pan T-cell antibody. Studies were performed to investigate the relationship between EPF levels during normal first trimester intact pregnancies and therapeutic abortions. The change in EPF levels is compared with those of hormones after interrupted pregnancy.

Abortion, Therapeutic↗
PubMed1985

[Effect of various factors on in vitro fertilization (IVF) and embryo transfer in the human in clomiphene/hMG/hCG stimulated cycles].

In the present study we tried to analyse data obtained on the occasion of an in vitro fertilization programme at the department of obstetrics and gynecology of the University of Kiel, to extract some of the important factors, because their positive or negative influence on the success of extracorporal insemination, embryo transfer and implantation has not been clearely defined till now and to value their concern. Between July 1982 and February 1983 105 sterile patients with ovulatory menstrual cycles have been treated by the technique of in vitro fertilization and embryo transfer, successively. Follicular growth was stimulated by 150 mg clomiphen daily from 3rd to 7th day and application of 225 IU hMG on 6th, 8th and 10th day. Finally ovulation was timed 36 hours before follicular puncture by 5000 IU hCG. In 24 per cent endogenous LH peak could be observed. In 86 per cent of the 80 patients exactly timed one oocyte was to be found minimally. In 68 per cent of these patients after all an embryo transfer was done (24 times one embryo, 13 times two, 9 times three and once four embryos). 89% of the embryos have been transfered as 4-or 8-cell stage, only 11 per cent as two cell stage. Transfer took place 48 to 50 hours following insemination. There was no correlation between the maturity classified morphologically of the oocytes and the diameter of their follicles. The speed of development of the embryos was not correlated with the size of their follicles. too. In 60-70 per cent of all cases, in which an embryo transfer was possible, husbands had normal spermiogram. The percentage of unfertilised oocytes following insemination using non-optimal sperma was increased in all types of cycles, additionally there was a reduction of the developing speed of resulting embryos. Doubtless two the four pregnancies resulted after insemination using sperma of less quality. The conjugation rate is said to be not correlated directly with the exactness of timing of the application of hCG with reference to follicular maturity, but in all pregnancies hCG was injected simultaneously with the peak of estradiol.

Chorionic Gonadotropin↗