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Biomedical subjects

K Seide

Publications and source records attributed to K Seide.

8 recordsLinked to original sources

[Corrections using the hexapod].

The hexapod is a construction that has been subjected to a great deal of investigation in robotics for use in three-dimensional positioning. One use of it is for positioning of the cockpit in flight simulators. Application of the hexapod principle in the external fixator makes it possible to realize prescribed movements of bone fragments with a simple and stable design. The precise setting of the system requires software that has been developed and optimized for clinical use. Translations, axis corrections and rotations are possible individually and also in combinations for correction of complex deformities. The system has advantages, especially in the case of rotations around the longitudinal axis of the bone and in the realization of translation movements. Because the centres of rotation are taken into account by the mathematical calculations, the planning of corrections is simplified. The hexapod system is described, and its clinical application is presented with reference to case reports.

Adult↗

Fracture reduction and deformity correction with the hexapod Ilizarov fixator.

A configuration for the Ilizarov external fixator with six distractors and 12 ball joints in the form of a hexapod was developed. The system allows for six degrees of freedom bone fragment displacement by controlling the distractors. Using this assembly, universal three-dimensional corrections or reductions are possible without the need for complicated joint mechanisms. The device was used in 16 patients: five had displaced tibial fractures with severe soft tissue damage, 10 had deformities or pseudarthroses subsequent to treatment of tibial fractures, and one had an axis deviation in the course of tibial lengthening. Translational (to 40 mm) and rotational deformities (to 33 degrees) were corrected. Final radiographic examinations after the correction procedure was complete showed median residual deformities of 3.5 mm (range, 0-5 mm) and 1 degree (range, 0 degree-4 degrees) in the anteroposterior projection and of 1.5 mm (range, 0-6 mm) and less than 1 degree (range, 0 degree-9 degrees) in the lateral projection. The construction is a useful and important addition to the Ilizarov fixator system. As a bone fixation device it is unique in that its optimal use depends on the availability of computer software.

Adolescent↗

[Universal 3-dimensional correction and reposition with the ring fixator using the hexapod configuration].

A new configuration for the Ilisarov fixator with 6 distractors and 12 ball joints in the form of a hexapod is proposed. Using this assembly, a correction or reduction is possible with respect to any given point and axis in space. The primary position of the rings is not critical. The fixator system is statically determined and there is no stress between the longitudinal rods. Difficult corrections like those necessary for rotational deformities can be done without complicated joint mechanisms.

Biomechanical Phenomena↗

[Significance of isthmic spondylolisthesis in expert assessment of occupational disease of the lumbar spine].

In Germany, disc-related disease of the lumbar spine is eligible for workmen's compensation if caused by long-standing work requiring heavy lifting or carrying or extreme trunk-bending (BK 2108). The appraisal of causality is particularly difficult if conditions like isthmic spondylolisthesis preexist. 250 consecutive appraisals in nurses concerning the BK 2108 were analysed, 12 applicants (4.8%) had isthmic spondylolisthesis (4.6% of females and 5.9% of males). The literature about the natural history of isthmic spondylolisthesis is reviewed. A person who has isthmic spondylolisthesis is up to 25% more likely to have significant back trouble during his life than one who does not. Back pain in adults associated with spondylolisthesis is usually heralded by back pain in the late teens or early twenties. Progression of the slip is rarely seen after maturity. Due to the loss of protection by the posterior elements the disc is prone to premature degeneration which, however, does not become clinically apparent in most cases. Longstanding vocational heavy lifting or excessive stooping can negatively influence the natural history of isthmic spondylolisthesis. It can produce symptomatic disease in a person who would otherwise have remained asymptomatic, or it can cause a deterioration in those with preexisting symptoms. Criteria for the appraisal of causality are proposed. It is stressed that the course of the disease in relation to age and vocational strains has to be analysed in each individual case.

Adolescent↗

[Standardized ultrasound study with computer-assisted documentation of findings in diagnosis of polytrauma patients].

Based on the results of a prospective trial to establish the value of routine ultrasound examination in cases of polytrauma or blunt abdominal trauma, we report on our standard ultrasound examination and computer assisted documentation of the findings. Between May 1988 and December 1990 we examined 233 patients with polytrauma or blunt abdominal trauma. The results were compared with those of abdominal lavage (n = 47) performed during the same period. We found a sensitivity of 100% and a specificity of 99.5% for the ultrasound findings and a sensitivity of 80% and a specificity of 100% for the abdominal lavage. We conclude that ultrasonography should be the first diagnostic procedure used in the emergency room in cases of polytrauma and blunt abdominal trauma.

Abdominal Injuries↗

[The effect of an angle-stable plate-screw connection and various screw diameters on the stability of plate osteosynthesis. An FE model study].

In a finite element model of a human femur with an attached stainless steel six-hole plate exposed to a load equivalent to that set up by standing on one leg, pressures on the face of the screw holes, bending stresses in the screws, and axial bone stresses in the mid-plate transverse section were determined. The calculations were performed for minor thread diameters of 3 mm, 5 mm and 8 mm. Further calculations were done assuming a fixator-like rigid screw-plate connection. As a model of a fracture a medial bone defect was chosen. The results show a definitive influence of the screw diameter and the screw-plate connection on the load distribution in the system. Increasing screw diameter makes for lower bone stresses combined with increased bending stability, a larger part of the load being carried by the plate. The rigid screw-plate connection (plate fixator) causes less bone stresses, but high bending stresses are set up the points of screw-plate fixation. Maximal stresses for screw and bone are found at the end of the plate, caused by the large difference in the E-module between the steel plate and the bone. End-plate bone and screws are loaded in excess of their material limits when 3 mm core diameters are used, and sometimes when 5 mm core diameters are used, under the assumed conditions. When a medial bone defect reducing the bone cross-sectional area by 44% is present, the loads on the inner screws increase by a factor of 3 and the loads of the distant screws, by a factor of only 1.3. The maximal pressure in the bone cross section increases 4-fold.

Biomechanical Phenomena↗

Three-dimensional dynamic x-ray-computed tomography imaging of stomach motility.

The dynamic spatial reconstructor (DSR), an x-ray-computed, tomography-based imaging machine, scans a cylindrical volume up to 39 cm in transaxial diameter and 21.5 cm in axial height with scan repetition rate up to 60 per second. We applied this technique to three dogs in order to investigate the accuracy with which stomach shape, dimensions, and motility can be measured. Single peristaltic waves of one dog's stomach filled with air and two other dogs' stomachs filled with different volumes of contrast-enhanced semisolid meals (10% Gastrografin) were scanned at 2-s intervals at scan apertures between 0.011- and 1-s duration. On completion of the scan sequence, images of oblique sections perpendicular to the local long axis of the stomach fundus, corpus, and antrum were computed from the DSR scan data. Measurements of differential motion of defined points on the stomach wall surface, propagation velocities, acceleration, and amplitudes of peristalsis as well as gastric volume determinations were made. This approach overcomes problems of superposition and ambiguity inherent in projection imaging. Measurements of the volumes of ingested first meal were accurate to within 1.5% (of the actual volume of solid food introduced into the stomach) using a 0.40-s scan aperture. Wall motion could be detected with an SEE of 1.5 mm (pixel size used was 1.4 mm) using a 0.40-s scan aperture.

Animals↗

The influence of tilidine and prazepam on withdrawal reflex, skin resistance reaction and pain rating in man.

Pain rating, withdrawal reflex and skin resistance reaction upon electrical skin stimuli were studied on 15 male volunteers under placebo, tilidine and prazepam. Tilidine (Valoron) is an orally applicable narcotic analgesic, with a mode of pain relief presumably similar to morphine; the tranquilizer prazepam (Demetrin) belongs to the benzodiazepine group. Significant reduction in all measured reaction amplitudes was found under tilidine, whereas prazepam reduced significantly only the skin resistance reaction. The relative drug-induced changes in reaction amplitudes, related to the corresponding placebo value, were independent of stimulus intensity for all investigated reactions. Therefore, fitted power functions re = a . Sn between reaction amplitudes re and stimulus intensity S showed a decrease in parameter a under the investigated drugs, whereas the exponent n remained constant. High correlations between parameters a and corresponding reciprocal threshold currents could be shown for all reactions measured. Furthermore the drug-induced changes of withdrawal reflex amplitude and of subjective estimation were found to be correlated over subjects. In contrast, no correlations were found between variations in skin resistance reaction and magnitude estimation due to the selected drugs, i.e., the influence of the drugs on the sensory component of pain sensation and on the skin resistance reaction were independent effects.

Analgesia↗