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K Sedlarik

Publications and source records attributed to K Sedlarik.

88 records · Page 5Linked to original sources
PubMedDate not supplied

[Effective forms of surgical dressing materials produced by the Paul Hartman firm].

From study of gauze dressings produced by the Paul Hartman firm the authors analyse the approaches to their elaboration. It is shown that the use of industrially sterilized gauze dressing-material creates the condition for fruitful work of the surgeon and ensures economy of the gauze. Concrete problems of the production of modern gauze dressing material by Soviet industry are defined.

Bandages↗
PubMedDate not supplied

The use of proteases as thrombolytic agents from the toxicological point of view.

In case of systematic hyperproteolysis in the blood of experimental animals after application of ocrase, a fibrinolytically active protease from Aspergillus ochraceus, toxic side effects, particularly on hemostatis and cardiac action, were observed. In order to prevent toxic effects, ocrase in thrombolytic therapy is to be administered within the inhibitor level. After daily administration of 5.6 mg/kg of ocrase (50% of inhibitor level) to rats, toxicological examinations over four weeks showed no deviation from the regular hematological and biochemical values. The thrombolytic effect of ocrase is explained by the formation of an inhibitor-ocrase complex which acts thrombolytically in the presence of fibrin.

Animals↗