The effect of customary Finnish heat preparation methods on the infestiveness of Diphyllobothrium latum from fish to man.
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Animals↗
Biomedical subjects
K Salminen
Publications and source records attributed to K Salminen.
Response of plasma immunoreactive beta-endorphin and corticotropin to isometric exercise in uncomplicated pregnancy and in pregnancy-induced hypertension.
The response of plasma immunoreactive beta-endorphin (ir-beta E) and corticotropin to isometric exercise was studied in 10 women with pregnancy-induced hypertension (PIH) and in nine healthy women subjected to a handgrip test in the third trimester of gestation. The mean basal concentration of corticotropin was higher in the PIH than in the control group, 3.8 +/- 0.3 (SE) pmol/l and 2.2 +/- 0.2 pmol/l, respectively (p = 0.002). No significant difference was found in the basal ir-beta E level, 6.9 +/- 0.9 pmol/l and 6.1 +/- 1.0 pmol/l, respectively. In response to the handgrip test, the corticotropin and ir-beta E concentrations rose significantly in all subjects (p = 0.001 and p = 0.02, respectively) without any significant differences between the groups. These findings indicate that an isometric exercise is sufficient to increase the secretion of ir-beta E and corticotropin during pregnancy. Increased basal concentration of corticotropin in women with PIH may be explained by significantly increased circulating corticotropin-releasing hormone, 1451 +/- 323 pmol/l, as compared to 528 +/- 190 pmol/l in the control group.
Adrenocorticotropic Hormone↗
Localization and concentrations of beta-endorphin and beta-lipotrophin in human placenta.
Immunohistochemical staining of placental tissue for beta-endorphin immunoreactivity was positive in the syncytiotrophoblast in both early and term pregnancy. Cation-exchange liquid chromatography and radioimmunoassay revealed peaks of beta-endorphin and beta-lipotrophin and a third immunoreactive peak of unknown nature. The concentration of beta-endorphin was higher in the placental tissue than it was in the maternal or cord plasma. beta-Lipotrophin was not detected in all placentae studied. We did not find any effect of gestational age on tissue concentrations of endorphins in the placenta, nor was there any significant difference in the placental endorphin content between placentae collected at elective caesarean section before labour and after spontaneous vaginal delivery.
Female↗
Immunoreactive corticotropin-releasing factor and corticotropin during pregnancy, labor and puerperium.
Concentrations of immunoreactive corticotropin releasing factor (CRF) and corticotropin (ACTH) in the plasma were studied in healthy pregnant women. Concentration of CRF was near the detection limit of the assay (2.5 pmol/l) until the 16th week of pregnancy, increasing thereafter significantly towards term: the mean values (+/- S.E.) at weeks 8-11, 12-15, 16-19, 20-23, 24-27, 28-31, 32-35, and 36-40 were 2.9 +/- 0.42, 2.9 +/- 0.72, 5.2 +/- 1.1, 10.2 +/- 5.8, 14.6 +/- 2.0, 32.8 +/- 4.8, 63.6 +/- 9.2, and 187 +/- 39 pmol/l, respectively. The mean concentration of CRF did not increase during labor, and it decreased rapidly after delivery. On the contrary, the mean plasma level of ACTH increased only slightly during late pregnancy, but during labor the increase was significant. These findings suggest that CRF in maternal circulation is not primarily involved in the regulation of maternal ACTH secretion, and the stress of labor does not increase the release of CRF, which probably originates mainly from the placenta.
Adrenocorticotropic Hormone↗