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Biomedical subjects

K SCHMIDT-NIELSEN

Publications and source records attributed to K SCHMIDT-NIELSEN.

At least 19 recordsLinked to original sources

DIABETES MELLITUS IN THE SAND RAT INDUCED BY STANDARD LABORATORY DIETS.

During an attempt to establish a laboratory colony of the sand rat (Psammomys obesus) we found that this animal invariably became obese and developed severe diabetes mellitus when fed on commercial laboratory rat feed, but remained normal when fed on fresh vegetables only. The signs of diabetes included elevated blood glucose, excessive glucose and ketone bodies in the urine, and cataracts. The diabetic animals showed degeneration of the pancreatic insulin producing tissue (beta-cells).

Animals↗

Secretion of iodide by the nasal gland of birds.

The nasal gland of the gull can secrete a solution of sodium chloride about 5 to 6 times more concentrated than that found in blood plasma. The gland can also concentrate iodide to several times the plasma concentration, but chloride seems to be preferred in the secretory process. These experiments were undertaken in the hope that a particularly high iodide clearance could form the basis of a method for determining the blood flow to the gland. The results made this approach to blood flow measurements unfeasible.

Animals↗

Salt glands.

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Animals↗