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Biomedical subjects

K S Oh

Publications and source records attributed to K S Oh.

At least 73 records · Page 4Linked to original sources

Paraspinal interfaces in the lower thoracic area in children: evaluation by CT.

Computed tomography was used to examine the three paraspinal interfaces (lines), consisting of the right and left paraspinal areas and the prespinal area in the lower thorax in 20 children. The abnormal CT findings were correlated with plain radiographic findings. The various disease contributing to paraspinal abnormality included malignant and benign neoplasm and inflammatory disease. Neuroblastoma was the most common entity. Fourteen of 20 patients had paraspinal masses representing either metastasis or lymphoma. Four had small pleural effusions and two had a combination of small pleural effusion and masses. Plain radiographs also showed the paraspinal masses, except in the prespinal area, where four of seven abnormalities seen with CT were not detected with plain radiographs. CT also better demonstrated the extent of involvement than did plain radiography.

Child↗

Ultrasonographic evaluation of the gallbladder in mucocutaneous lymph node syndrome.

Hydrops of the gallbladder was diagnosed by ultrasonography in five out of ten consecutive patients with mucocutaneous lymph node syndrome (MLNS). Certain signs and symptoms were correlated with the development of hydrops. Follow-up ultrasonography revealed the return of the gallbladder to normal size in four out of four patients. One patient was lost to follow-up. Hydrops of the gallbladder in patients with MLNS appears to be a self-limiting condition with a benign course.

Child↗

Uncomplicated trigonocephaly. A radiographic affirmation of conservative therapy.

Trigonocephaly is a relatively rare deformity of the skull characterized by triangular prominence of the bones of the forehead and orbital hypotelorism. Long-term results in a group of patients with clinical and radiographic follow-up are analyzed, the radiographic findings reviewed, and possible etiologies discussed. The etiologic relationship between premature synostosis of the metopic suture and trigonocephaly is questioned. Uncomplicated trigonocephaly is a self-limited, self-correcting deformity, and a normal cosmetic appearance develops without surgical treatment. Surgical craniectomy as treatment for uncomplicated trigonocephaly is not indicated on the basis of the authors' experience.

Female↗

The Drash syndrome: male pseudohermaphroditism, nephritis, and Wilms tumor.

We report the radiographic and clinical findings of five infants and children who had the combination of male pseudohermaphroditism, progressive nephritis, and Wilms tumor. The components of this syndrome are so striking that the radiologist can often suggest the diagnosis months to years before all three components are apparent, if proteinuria, hypertension, or an abdominal mass develop in any child with male pseudohermaphroditism. Since the progressive renal failure probably can be managed by dialysis or renal transplantation in some cases, prompt recognition and treatment of the Wilms tumor may permit the child to live a long and relatively normal life.

Disorders of Sex Development↗

Patent ductus arteriosus. Its occurrence with unequal pulmonary vascularity and hyperlucent left lung.

Twenty-four of 230 patients with patent ductus arteriosus had hypovascularity and hyperlucency in the left lung on preoperative chest roentgenograms. Two of the 24 patients died shortly after operation, and one was unavailable for follow-up. During the postoperative course (mean, three years), roentgenograms of eight of the remaining 21 patients showed persistent, unequal pulmonary vascularity and hyperlucent left lung, with no evidence of air trapping, and two patients had diminished volume of the hyperlucent left lung compared with that of the right lung.

Bronchography↗

Unilateral inguinal hernias in children: What about the opposite side?

The decision for or against bilateral exploration in unilateral hernias in infants is necessitated by the high incidence of obscure anatomic hernias on the opposite side. On the basis of studies done in 400 pediatric patients (mostly under 2 years of age), we believe that unilateral repair of a known hernia without ascertaining the presence of a contralateral hernia is unjustified. Because of an appreciable risk to the gonads and/or vas deferens, we do not believe routine bilateral herniorrhaphies in all infants are indicated. The attempts at an intraoperative, transperitoneal insertion of a Bakes dilator into a contralateral sac were unreliable in our hands. Herniography is a reliable, safe way to reduce the incidence of unnecessary contralateral exploration. It should be liberally used where the necessary radiologic expertise is available.

Hernia, Inguinal↗

Nutritional rickets in 2 very low birthweight infants with chronic lung disease.

Two very low birthweight infants with rickets are described; one had a low serum 25-hydroxy-vitamin D3 concentration. Similarities in their clinical courses included low birthweights, low calcium intakes, uncertain vitamin D intakes, and chronic administration of frusemide and sodium bicarbonate--all potential aetiological factors in the development of bone undermineralisation. Both infants had a resolution of their chronic lung disease before their treatment for rickets. This experience has led us to the more cautions use of frusemide and sodium bicarbonate in infants at risk for rickets, and shows the need to ensure daily vitamin D supplements.

Bicarbonates↗

The bulbous bowel segment: a sign of congenital small bowel obstruction.

A study of 29 neonates with intestinal obstruction has shown that a massively dilated, bulbous terminal segment of bowel is characteristic of neonatal infestinal obstruction of congenital origin. The sign is an important diagnostic indicator but its absence does not exclude intestinal atresia.

Dilatation, Pathologic↗

Calcification in childhood leiomyoma.

Leiomyoma is a benign, smooth-muscle tumor which rarely affects children. Calcification in this tumor is unusual. Two boys, aged three and six years, had large axillary leiomyomas with "mulberry" calcifications similar to those seen in calcified uterine leiomyoma. The lesions did not recur after total surgical excision.

Axilla↗

Coexistent neuroblastoma and Hirschsprung's disease--another manifestation of the neurocristopathy?

Abnormalities of neural crest development may be manifested in a wide variety of ways ranging from von Recklinghausen's disease to Sipple's syndrome -- pheochromocytoma and medullary thyroid carcinoma. We report here yet another manifestation -- coexistent multiple neuroblastomas and Hirschsprung's disease in a newborn. In a review of the English literature we have found the combination of neuroblastoma and Hirschsprung's disease recorded only once previously [2]. However, the relationship between the two diseases was not discussed. The two diseases may be at the extremes of a spectrum of neural crest development pathology, i.e., Hirschsprung's representing a deficiency and neuroblastoma representing malignant proliferation of cells of neural crest origin.

Abdominal Neoplasms↗

Traumatic aneurysm of the ascending aorta in a child.

A case of traumatic aneurysm of the ascending aorta in a child is reported. This complication must be suspected in a child who sustains severe injury from closed thoracic trauma and develops an abnormally wide anterior mediastinum. A mechanism for ascending aortic rupture and aneurysm is proposed. Aortography is essential when aortic injury and its complications are suspected.

Angiography↗

Urologic manifestations of sickle hemoglobinopathies.

We analyzed the renal radiographic changes in the sickle hemoglobinopathies in 92 patients, in 70 of whom the specific hemoglobin type was documented by electrophoresis. The following conclusions have been drawn: (1) Approximately 50% of patients with SS hemoglobin have renal enlargement (both on roentgenograms and at autopsy), while only a small proportion of patients with the other hemoglobinopathies show renal enlargement; (2) slightly more than one half of patients with each type of hemoglobinopathy have calyceal changes; and (3) these calyceal changes do not fall into a specific pattern with respect to hemoglobin type.

Adolescent↗

Computed tomographic positive contrast peritoneography.

Despite the use of intravenous and oral contrast material and antiperistaltic pharmaceuticals, abdominal computed tomography has limitations in the morphological study of the gastrointestinal tract, retroperitoneum, and pelvis. To better define these regions, positive contrast material was infused into the peritoneal space prior to abdominal CT. Results included: improved visualization of the peritoneal cavity and its contents; evident demarcation between the retroperitoneal space and intraperitoneal structures; sharp delineation of serosal surfaces of the bowel and solid viscera; and an obvious distinction between impinging bowel loops and pelvic organs.

Adult↗

Abnormal intestinal motility in gastroschisis.

The authors describe abnormal intestinal motility with a very slow transit time in eight children with gastroschisis. Other abnormal findings include malrotation, dilatation, and fixation of the loops of the bowel.

Abdominal Muscles↗