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Biomedical subjects

K S Ivanov

Publications and source records attributed to K S Ivanov.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Fibrocolonoscopy in patients with intestinal amebiasis].

Fibrocolonoscopy findings from 131 diarrhea patients proved the procedure valuable for early diagnosis of amebiasis and control of the treatment efficacy. Fibrocolonoscopy helps to establish the true picture and the scope of the colon mucosa involvement, identification of dysenteric ameba trophozoites in the mucosal bioptic specimens being the final diagnostic criterion. The procedure facilitates regulation of the treatment duration. In the study the recovery in the mild disease was documented 25-30 days after the treatment onset, in moderate-severity contamination it took 40-45 days to eliminate the infection.

Adolescent↗
PubMed1982

[Clinical laboratory basis for using kanamycin sulfate for treating meningococcal meningitis].

Satisfactory penetration of lincomycin sulfate through the hematoencephalic barrier was shown in experimental meningococcic meningitis of rabbits and in treatment of patients with meningococcic meningitis. Constant high levels of the antibiotic in the cerebrospinal fluid, meninx vasculosa, penetration into the brain tissues may be achieved after intramuscular injection of the drug in a dose of 500 mg every 8 hours. The study showed therapeutic efficacy of kanamycin in the treatment of the patients with meningococcic meningitis. It may be recommended for the clinical use as a reserve antibiotic. As an independent etiotropic agent kanamycin may be used in sensitivity to benzylpenicillin or its inefficiency in treatment of the meningococcic infection. Kanamycin may be used in combination with benzylpenicillin in severe forms of meningitis, meningoencephalitis or purulent meningitis of an unknown etiology.

Animals↗
PubMed1981

[Clinical and experimental rifampicin passage through the hemato-encephalic barrier and its effectiveness in treating meningococcal infections].

Satisfactory permeability of rifampicin through the hematoencephalic barrier was shown in experimental rabbit meningococcal meningitis and in treatment of patients with meningococcal meningitis. The antibiotic level and retention time in the liquor depended on the drug dose and acidity of gastric juice. The dose of 10 mg/kg bw administered at 8--10-hour intervals was the most optimal. The high therapeutic efficacy of rifampicin in treatment of patients with the generalized forms of meningococcal meningitis enables its recommendation for the use as a reserve drug. Rifampicin may be used alone when penicillin is intolerable or ineffective. It also may be used for additional treatment of the patients after penicillin therapy. Rifampicin in combination with penicillin may be used in treatment of purulent meningitis and meningoencephalitis of a dubious etiology.

Animals↗