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Biomedical subjects

K Ryu

Publications and source records attributed to K Ryu.

47 records · Page 3Linked to original sources

The effect of combined oral contraceptive steroids on the gonadotropin responses to LH-RH in lactating women with regular menstrual cycles resumed.

The effect of combined oral contraceptive steroids upon pituitary response to stimulation with 100 micrograms LH-RH was studied in both non-puerperal and lactating women with regular menstrual cycles. Serum prolactin concentration was 14.20 ng/ml in non-puerperal women whereas it was 39.37 ng/ml in lactating women. A comparability was shown in the LH response to LH-RH in non-puerperal women and lactating women. FSH response to LH-RH, however, was significantly exaggerated in lactating-menstruating women as compared to that of non-puerperal women. Combined oral contraceptive steroids lowered basal levels of LH and FSH in non-puerperal women and lactating women although the difference was not statistically significant in non-puerperal women. The LH and FSH maximal responses to LH-RH were significantly diminished in both non-puerperal and lactating women on combined oral contraceptives. There was, however, no difference in the mean LH or FSH responses between non-puerperal women and lactating women. Combined oral contraceptive steroids used in this study seemed to suppress ovulation by decreasing the pituitary responsiveness to LH-RH in lactating-menstruating women as well as in normally menstruating women.

Contraceptives, Oral↗

The mesencephalic root fibers of the trigeminal nerve in the dog.

The trigeminal nerve has motor, intermediate and sensory roots in the dog. The motor root is composed of two bundles: the medial and ventral. The ventral motor root emerges from the pons, forming the common root with the sensory, and then is separated from it to run along with the medial motor root which separately exits from the pons as the ordinary motor root. The mesencephalic root fibers of the trigeminal nerve are investigated in the dog, using the myelin sheath degeneration technique. Degenerated fibers are observed numerously in the ventral motor root and moderately in the medial motor root, and are traced to the mandibular branch of the trigeminal nerve. Some degenerated fibers are observed in the sensory root and they seem to pass through the Gasserian ganglion to enter the ophthalmic and maxillary branches. No degenerated fibers are found in the intermediate root.

Animals↗

Absorption rates of L-tryptophan, L-methionine, and L-methionyl-L-tryptophan by rat intestine in vitro and in vivo.

The absorption rates of L-tryptophan, L-methionine, and L-methionyl-L-tryptophan were determined by both the everted sac and the tied loop method with rat intestines. In the everted sac method, high concentrations of L-tryptophan or L-methionyl-L-tryptophan caused anomalous inhibition of absorption of L-tryptophan and L-methionine. The rates of absorption of both L-tryptophan and L-methionyl-L-tryptophan decreased markedly at concentrations higher than 2-3mM. This inhibition was not observed in the tied loop method. Chromatographic, electrophoretic, and microscopic studies suggested that such decreases in absorption rate were caused mainly by decomposition of L-tryptophan to some basic incubation products containing tryptamine with consequent damage to the mucosal surface of everted sacs during long-term incubation. In the tied loop method, L-methionyl-L-tryptophan was absorbed more rapidly than either of the constituent amino acids in equimolar mixture.

Animals↗