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Biomedical subjects

K Rose

Publications and source records attributed to K Rose.

168 records · Page 10Linked to original sources
PubMedDate not supplied

Volume reduction of arm lymphoedema.

Most of the volume reduction in an 11-day course of compression bandaging for severe cancer-related arm lymphoedema appeared to occur in the first few days. This study therefore compared the volume loss during days 1-4 with 5-11. Fifteen consecutive courses of bandaging were studied. Arm volume was estimated on days 1, 5 and 11. The volume reduction during days 1-4 was compared with days 5-11 using the Wilcoxan Ranked Pairs Test. Seventy nine per cent of the total median volume reduction occurred during days 1-4. The difference between the two periods was highly significant (p < 0.001). The duration of compression bandaging has therefore been reduced to 4 days for severe cancer-related arm lymphoedema in this clinic.

Bandages↗
PubMedDate not supplied

[Superiority of pantoprazole over ranitidine in the treatment of duodenal ulcer. Mexican clinical experience. Mexican Study Group of Pantoprazole++ in Duodenal Ulcer].

BACKGROUND: Pantoprazole is a new Proton Pump Inhibitor that has demonstrated to be superior to ranitidine in the healing of the acid related diseases. AIMS: To compare efficacy and tolerability of oral treatment with pantoprazole vs. ranitidine in outpatients with endoscopically confirmed florid duodenal ulcers in Mexican patients. METHODS: Prospective, multicentric, balanced, randomized, double blind, parallel group comparison clinical trial. Each patient received 40 mg pantoprazole plus placebo or 300 mg ranitidine plus placebo once daily for 2 weeks; if patients had not healed endoscopically by then, treatment was continued for two more weeks, with a final endoscopy. RESULTS: 163 protocol-correct patients were analyzed: 82 for pantoprazole group and 81 for ranitidine group. Healing rates at week 2 were 72% for pantoprazole and 51% for ranitidine (p < 0.01) and correspondingly 95 and 86% at week 4. The percentage of patients suffering from pain declined faster in the pantoprazole group. Both products were well tolerated and safe. CONCLUSIONS: Pantoprazole is well tolerated and significantly superior to ranitidine in florid duodenal ulcers healing.

2-Pyridinylmethylsulfinylbenzimidazoles↗