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Biomedical subjects

K Rawal

Publications and source records attributed to K Rawal.

4 recordsLinked to original sources
PubMed1995

Incidence and spread of Haemophilus influenzae on an Antarctic base determined using the polymerase chain reaction.

A PCR-based method of detecting Haemophilus influenzae in cultures inoculated from throat swabs was evaluated using samples from groups of laboratory staff and medical students and then applied to samples originating from the closed human community of an Antarctic research station. Suitable PCR primers to an H. influenzae gene (ompP2) were used to amplify the gene from DNA preparations made from mixed growth on chocolate agar with added vancomycin. PCR product was reamplified and subjected to restriction endonuclease digestion to allow temporal and spatial mapping of strains over an 8-month period. Eleven different strains of H. influenzae were detected. One particular strain was detected in a third of the base members.

Adult↗
PubMed1985

Status epilepticus.

Status epilepticus represents a true medical emergency that can affect all age groups. Failure to adequately treat this problem can lead to potentially serious systemic and neurologic complications. Management strategies should include stabilization of the cardiovascular and respiratory status of the patient, use of anticonvulsants intravenously and in proper doses, search for a cause, and maintenance therapy.

Brain Damage, Chronic↗
PubMedDate not supplied

Visual and somatosensory evoked potentials in vitamin E deficiency with cystic fibrosis.

Patients with cystic fibrosis (CF) and pancreatic malabsorption frequently have vitamin E deficiency. Affected patients may develop spinocerebellar degeneration with dysarthria, ataxia, proximal weakness, proprioceptive loss and areflexia. Of a highly selected group of 10 patients with vitamin E levels below 5 micrograms/ml (normal 5-20 micrograms/ml), 7 had abnormal neurological examinations, predominantly affecting vibration and joint position perception with some severely affected patients manifesting diminished visual acuity, tremor, ataxia and diffuse weakness. Evoked potential studies showed marked abnormalities in 3 patients, demonstrating deficits in the optic pathways and in the cervical cord dorsal column pathways. Evoked potential studies may supplement careful neurological examination in patients with CF before and after supplementation with vitamin E to evaluate their progression and response to treatment.

Adolescent↗