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Biomedical subjects

K R Ramakrishnan

Publications and source records attributed to K R Ramakrishnan.

7 recordsLinked to original sources
PubMed1989

Drug eruptions (a series of 148 cases).

A total number of 148 patients, comprising of 101 males and 47 females diagnosed as drug eruptions were reviewed. The youngest patient was eight and the oldest 73 years. The mean age was 34 years. 75(50.7%) patients were in the age group of 20 to 40 years. In 88(59.5%) pruritus was the chief associated symptom. 116(78.4%) developed eruptions within 2 weeks. 29(19.6%) had single site involvement, 92(62.2%) had lesions at more than one site and 25(16.9%) patients had generalised skin and mucous membrane involvement. The commonest skin reactions were fixed drug eruptions in 39(26.4%) cases. Almost all types of drug eruptions were observed. The eruptions were caused by 37 different drugs, the commonest being sulphonamides in 28(18.9%) cases. Systemic side effects were recorded in 13(8.8%) patients. 76(51.4%) were treated with topical medicaments. Out of the remaining, 33(22.3%) were managed by antihistamines and 26(17.6%) by steroids in addition to topical therapy. No treatment was required in 13(8.8%). 117(79.1%) were treated as out patients and 31(20.9%) were hospitalised. One (0.7%) patient died of toxic epidermal necrolysis due to penicillamine.

Adult↗
PubMed1989

Analysis of dermatological referrals (a series of 662 cases from base and army hospital complex).

An analysis of 662 patients from non-dermatological wards and specialist out-patients referred for dermatological opinion is reported. There was a high proportion of referrals of 330 (49 8%) cases from internal medicine and allied specialties, followed by 150 (22.7%) from surgical disciplines, 65 (9.8%) by Paediatricians 30 (4.5%) by Otolaryngologists, 24 (3.6%) each by Ophthalmologists and specialists in Obstetrics and Gynaecology, 21 (3 2%) by dental surgeons and 18 (2.7%) from department of Psychiatry. The youngest patient was a new born and the oldest 87 years. 333 (50.3%) were in the age group of 21 to 40 years. 505 (76.3%) were males. Almost one fourth i.e. 152 (23%) presented with cutaneous manifestations of underlying diseases, another 82 (12.4%) were drug eruptions and other complications of treatment. The study emphasizes considerable interphase between cutaneous and systemic diseases and the need for close co-operation between dermatology and other specialist medical disciplines.

Adolescent↗
PubMed1988

Paucibacillary leprosy: a comparative study of different schedules of multidrug therapy.

The study was undertaken to evaluate the efficacy of various multidrug regimens (MDT). Three groups of 10 cases each of Paucibacillary cases were given different schedule of multidrug therapy. First group (T-0) was administered modified WHO regimen consisting of Rifampicin 600 mg once a month, Clofazimine 100 mg alternate days and Dapsone 100 mg daily for 6 months. In second group (T-1) Rifampicin 600 mg was given daily for 6 weeks and in third group (T-2) Rifampicin 600 mg was given daily for 6 months. In both the latter groups Clofazimine 100 mg on alternate days and Dapsone 100 mg daily was also administered for 6 months. Objective clinical scoring was done at the time of admission, three months and six months after treatment in all three groups. The best results were obtained by T-2 followed by T-1; and least effective was T-0 regimen. Pinkish colour of urine and skin was observed in 26 cases and icthyosis in all the cases. All the patients remain under treatment. The work is in progress and subsequent results will be published later.

Adult↗
PubMed1987

Moustachology.

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Hair↗