Biomedical subjects
Publications and source records attributed to K R Mecke.
Quantitative predictions are presented of a depletion-induced torque and force acting on a single colloidal hard rod immersed in a solvent of hard spheres close to a planar hard wall. This torque and force, which are entirely of entropic origin, may play an important role for the key-lock principle, according to which a biological macromolecule (the key) is functional only in a particular orientation with respect to a cavity (the lock).
We consider a family of statistical measures based on the Euler-Poincaré characteristic of n-dimensional space that are sensitive to the morphology of disordered structures. These measures embody information from every order of the correlation function but can be calculated simply by summing over local contributions. We compute the evolution of the measures with density for a range of disordered microstructural models; particle-based models, amorphous microstructures, and cellular and foamlike structures. Analytic results for the particle-based models are given and the computational algorithm verified. Computational results for the different microstructures exhibit a range of qualitative behavior. A length scale is derived based on two-point autocorrelation functions to allow qualitative comparison between the different structures. We compute the morphological parameters for the experimental microstructure of a sandstone sample and compare them to three common stochastic model systems for porous media. None of the statistical models are able to accurately reproduce the morphology of the sandstone.
Starting from a density functional theory for inhomogeneous fluids we derive an effective Hamiltonian for liquid-vapor interfaces of simple fluids which goes beyond the common phenomenological capillary-wave description. In contrast to other approaches we take into account the long-ranged power-law decay of the dispersion forces between the fluid particles which changes the functional form of the wave-vector-dependent surface tension qualitatively. In particular, we find two different forms of the bending rigidity for the capillary waves, a negative one for small wave vectors determined by the long-ranged dispersion forces and a positive rigidity for large wave vectors due to the distortions of the intrinsic density profile in the vicinity of the locally curved interface. The differences to the standard capillary-wave theory and the relevance of these results for the interpretation of scattering experiments are discussed.