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Biomedical subjects

K R Kase

Publications and source records attributed to K R Kase.

At least 37 records · Page 2Linked to original sources

Radiation transmission study of silicone elastomer for mammary prosthesis.

Photon and electron transmission measurements were made for silicone elastomer and water, used in mammary prostheses. Photon energies used ranged from 100 kVp, 1.0-mm AI HVL, to 8 MV, and electron energies ranged from 3 to 11 MeV. Transmission of photons above 150 keV and electrons above 2 MeV through the silicone and water is identical, as expected from calculations of mass attenuation coefficients and mass stopping power.

Breast↗

Bremsstrahlung dose to patients in rotational electron therapy.

Dose and integral dose from bremsstrahlung in a 10-MeV electron beam were measured for irradiation of large areas with 120 degrees-arc rotational fields. The maximum bremsstrahlung dose ranged from 2% to 7% of the maximum electron dose for the different beam arrangements, while the integral dose showed the same range of variation. The concomitant bremsstrahlung beam should be collimated by the x-ray photon collimators and the use of narrow field rotations avoided.

Electromagnetic Phenomena↗

(MPC)a for 13N.

Explore the source record for details and available documents.

Environmental Exposure↗

Spectral energy effects in ESR bone dosimetry: photons and electrons.

The spectral energy-dependence of the radiation-induced ESR signal has been studied in ovine cortical bone. Crushed bone samples were irradiated using photon beams with effective energies in the range from 0.06 to 6 MeV, and electron beams with mean energies in the range from 2 to 10 MeV. The photon and electron data were normalized to a dose to bone of 50 Gy and the results are reported as response relative to the ESR signal for photon irradiation at 1.25 MeV (60Co). The photon irradiation results show that the ESR response is greatest at low energies with a relative value of 1.2 at 0.06 MeV. The relative response decreases, as the energy increases, to approximately 0.85 in the region of 2 to 3 MeV. These variations in the relative ESR responses are significantly less than the ESR energy-dependent responses reported in the literature for human tooth enamel and synthetic hydroxyapatite. An explanation for this difference is offered. For electron beam irradiations, the ESR signal is fairly constant with energy, and approximately equal to that at a photon energy of 1.25 MeV. Implications of these results are discussed.

Animals↗

Postal intercomparison of absorbed dose for high energy x rays with thermoluminescence dosimeters.

This study concerns the accuracy and precision of the IAEA/WHO LiF TLD system used in intercomparison by mail of absorbed doses from 60Co gamma-radiation and 4-25 MV x rays. The system employs 160 mg LiF powder in polystyrene capsules, which are placed at 5 or 7 cm depth in water and irradiated to doses close to 200 rad (2.00 Gy). The dosimeters are mailed to the IAEA Dosimetry Laboratory and read out under conditions to minimize variatons in instrument sensitivity. The precision of the readout technique, using 3 capsules per irradiation and the readout of 5 aliquots per capsule, is characterized by 0.2% standard deviation of the resulting mean. Since random errors during the irradiation are added, the detectable systematic descrepancy in dose delivery, at the 95% confidence level, is +/- 2% for 60Co gamma and +/- 3% for high-energy x rays.

Cobalt Radioisotopes↗

Spectral characterization of 4 MV Bremsstrahlung by attenuation analysis.

The "quality of radiation" for a high energy x-ray beam can be specified by its attenuation curve in a selected material. The inverse Laplace transform of the attenuation curve can be used as an approximate indication of the energy spectrum of the beam. Existing mathematical procedures for this purpose have been evaluated and were found to poorly represent measured transmission data for 4 MV x-rays from a linear accelerator. The transmission data between 1 and 0.002 could be fitted within the experimental uncertainty by expressing the logarithmic transmission as a second order polynomial of attenuator thickness. The inverse Laplace transform them becomes a Gaussian function of the attenuation coefficient. This new version of "attenuation analysis" provides a practical method for specification of the quality of the radiation in this energy range.

Models, Theoretical↗

Comparisons of electron beam dose measurements in water and polystyrene using various dosimeters.

A comparison has been made of central axis percent depth dose and absorbed dose in electron beams of 7.8 and 10.2 MeV, measured with devices of differing geometry and construction. Flat and cylindrical ionization chambers have been used as well as thin thermoluminescent dosimeters. The ionization chambers had walls of air equivalent or tissue equivalent plastic. Results indicate that central axis depth dose measurements are independent of measuring device. No significant difference was found among the various ionization chambers with air equivalent walls in the determination of absorbed dose. The dose determined by the tissue-equivalent wall chamber was about 3% higher than the dose determined by the other ionization chambers. Dose maximum on the central axis in water is about 4% greater than when this same quantity is calculated from data measured in polystyrene.

Electrons↗

Simulation studies of 4-MV x-ray spectral reconstruction by numerical analysis of transmission data.

The use of transmission measurements with combinations of attenuating materials has been investigated as a method of determining the x-ray energy spectrum from a 4-MV linear accelerator. Simulation studies have been made with three 4-MV x-ray spectra of slightly different shapes. From each of these spectra, the narrow beam transmission curve was calculated, using lead to attenuate the beam for the first several points. Aluminum was then added to attenuate the beam to 0.001 of its initial intensity. A computer program using an iterative least-squares technique has been developed to analyze the transmission data and determine the spectrum by applying some physically reasonable sensible constraints. The calculated transmission values agreed with the simulated data within the estimated experimental uncertainties, and it is concluded that the technique is reliable for the spectral reconstruction and is sensitive to small spectral changes.

Computers↗

Reconstruction of 4-MV bremsstrahlung spectra from measured transmission data.

Transmission data for 4-MV bremsstrahlung beams have been measured with a combination of lead and aluminum attenuators. From these data, the original energy spectra have been reconstructed using an iterative least-squares technique, previously evaluated by simulation studies. The spectra on the central axis for three similar 4-MV linear accelerators indicated no significant differences. When studying the spectra at 5 degrees and 9 degrees off the central axis, that at 9 degrees showed the expected increase of low-energy photons. All these spectra showed a maximum photon energy of 4.5 +/- 0.2 MeV. When the magnetron power was reduced, the spectrum on the central axis shifted to lower energies and the maximum photon energy decreased to 3.5 +/- 0.2 MeV. The result of this experimental study confirms the conclusions from the previous stimulation, that the numerical technique for analysis of transmission data can accurately represent 4-MV bremsstrahlung spectra and detect differences in energy distribution with changes in machine tuning and position in the radiation field for a 4-MV bremsstrahlung beam.

Particle Accelerators↗

Replacement correction factors for photon and electron dose measurements.

A "gradient correction factor" and an "electron fluence correction factor" are used in the AAPM Task Group 21 dosimetry protocol, the product of the two being the "replacement correction factor." The separation of two physical processes, implied by the concepts, is theoretically unfounded. The proof of this statement rests on Fano's theorem, the conditions for which constitute a case without variations in fluence or its directional and energy distributions. Deviations from these conditions represent gradients in the radiation field, affect the response of a measurement cavity, and do so by perturbing the fluence of electrons that deposit energy in the cavity. Thus, in beams of both electrons and photons, corrections are required when fluence variations exist in the vicinity of the cavity. The rationale for an electron fluence correction based on "in-scattering" and "obliquity" is weak, since the effects only occur when gradients are present. The choice of values for the two correction factors at the depth of maximum dose are particularly inconsistent with the actual characteristics of the radiation field.

Electrons↗

Daily check instrument for photon and electron beam quality assurance of medical linacs.

An instrument for daily beam checks of medical accelerators is described. Using three silicon diodes, the instrument provides information about calibration, beam symmetry, flatness, and energy variation for both photon and electron beams. Operating characteristics of the instrument and the electronic circuit design permit simple and reliable measurements.

Biophysical Phenomena↗

Reconstruction of diagnostic x-ray spectra by numerical analysis of transmission data.

Numerical reconstruction of x-ray spectra from narrow-beam transmission data was tested with published spectra in the range from 45 to 100 kVp. Transmission curves were calculated from the spectra to simulate measured data. Spectra were reconstructed from these transmission curves with use of an iterative numerical analysis. Comparison of the calculated spectra with the original spectra shows good agreement, including the tungsten characteristic x rays. This demonstrates the potential usefulness of measured transmission data for deducing x-ray spectra in the diagnostic energy range.

Biophysical Phenomena↗